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Hematoxylin and eosin (H&E) staining visualizes histology but lacks specificity for diagnostic markers. Immunohistochemistry (IHC) staining provides protein-targeted staining but is restricted by tissue availability and antibody…

图像与视频处理 · 电气工程与系统科学 2025-07-01 Anran Liu , Xiaofei Wang , Jing Cai , Chao Li

Deformable medical image registration is traditionally formulated as an optimization problem. While classical methods solve this problem iteratively, recent learning-based approaches use recurrent neural networks (RNNs) to mimic this…

图像与视频处理 · 电气工程与系统科学 2025-07-09 Yi Zhang , Yidong Zhao , Qian Tao

Histopathology tissue samples are widely available in two states: paraffin-embedded unstained and non-paraffin-embedded stained whole slide RGB images (WSRI). Hematoxylin and eosin stain (H&E) is one of the principal stains in histology but…

计算机视觉与模式识别 · 计算机科学 2019-02-21 Aman Rana , Gregory Yauney , Alarice Lowe , Pratik Shah

In this paper, we propose a novel method for image fusion with a high-resolution panchromatic image and a low-resolution multispectral image at the same geographical location. The fusion is formulated as a convex optimization problem which…

计算机视觉与模式识别 · 计算机科学 2015-10-28 Chen Chen , Yeqing Li , Wei Liu , Junzhou Huang

Art technological investigations of historical panel paintings rely on acquiring multi-modal image data, including visual light photography, infrared reflectography, ultraviolet fluorescence photography, x-radiography, and macro…

计算机视觉与模式识别 · 计算机科学 2026-01-26 Aline Sindel , Andreas Maier , Vincent Christlein

Image registration plays an important role in medical image analysis. Conventional optimization based methods provide an accurate estimation due to the iterative process at the cost of expensive computation. Deep learning methods such as…

计算机视觉与模式识别 · 计算机科学 2021-06-21 Junshen Xu , Eric Z. Chen , Xiao Chen , Terrence Chen , Shanhui Sun

Image segmentation is a crucial but challenging task that has many applications. In medical imaging for instance, intensity inhomogeneity and noise are common. In thigh muscle images, different muscles are closed packed together and there…

计算机视觉与模式识别 · 计算机科学 2022-03-30 Haifeng Li , Weihong Guo , Jun Liu , Li Cui , Dongxing Xie

Hyperspectral image (HSI) densely samples the world in both the space and frequency domain and therefore is more distinctive than RGB images. Usually, HSI needs to be calibrated to minimize the impact of various illumination conditions. The…

计算机视觉与模式识别 · 计算机科学 2024-12-23 Zhuoran Du , Shaodi You , Cheng Cheng , Shikui Wei

Deep learning-based deformable registration methods have been widely investigated in diverse medical applications. Learning-based deformable registration relies on weighted objective functions trading off registration accuracy and…

图像与视频处理 · 电气工程与系统科学 2023-07-21 Haoran Dou , Ning Bi , Luyi Han , Yuhao Huang , Ritse Mann , Xin Yang , Dong Ni , Nishant Ravikumar , Alejandro F. Frangi , Yunzhi Huang

Methods for medical image registration infer geometric transformations that align pairs/groups of images by maximising an image similarity metric. This problem is ill-posed as several solutions may have equivalent likelihoods, also…

计算机视觉与模式识别 · 计算机科学 2024-03-19 Aisha L. Shuaibu , Ivor J. A. Simpson

Automated detection of mitotic figures in histopathology images is a challenging task: here, we present the different steps that describe the strategy we applied to participate in the MIDOG 2021 competition. The purpose of the competition…

计算机视觉与模式识别 · 计算机科学 2021-09-28 Maxime W. Lafarge , Viktor H. Koelzer

In clinical practice, well-aligned multi-modal images, such as Magnetic Resonance (MR) and Computed Tomography (CT), together can provide complementary information for image-guided therapies. Multi-modal image registration is essential for…

计算机视觉与模式识别 · 计算机科学 2022-04-29 Zekang Chen , Jia Wei , Rui Li

The rapid development of digital pathology and modern deep learning has facilitated the emergence of pathology foundation models that are expected to solve general pathology problems under various disease conditions in one unified model,…

计算机视觉与模式识别 · 计算机科学 2025-07-10 Yutong Sun , Sichen Zhu , Peng Qiu

This work proposes a multimodal diffeomorphic registration method using Neural Ordinary Differential Equations (Neural ODEs). Nonrigid registration algorithms exhibit tradeoffs between their accuracy, the computational complexity of their…

计算机视觉与模式识别 · 计算机科学 2025-12-30 Salvador Rodriguez-Sanz , Monica Hernandez

Breast cancer presents a significant healthcare challenge globally, demanding precise diagnostics and effective treatment strategies, where histopathological examination of Hematoxylin and Eosin (H&E) stained tissue sections plays a central…

图像与视频处理 · 电气工程与系统科学 2024-08-06 Linhao Qu , Chengsheng Zhang , Guihui Li , Haiyong Zheng , Chen Peng , Wei He

Image registration is the basis for many applications in the fields of medical image computing and computer assisted interventions. One example is the registration of 2D X-ray images with preoperative three-dimensional computed tomography…

计算机视觉与模式识别 · 计算机科学 2020-12-16 Darya Trofimova , Tim Adler , Lisa Kausch , Lynton Ardizzone , Klaus Maier-Hein , Ulrich Köthe , Carsten Rother , Lena Maier-Hein

Registration, which aims to find an optimal one-to-one correspondence between different data, is an important problem in various fields. This problem is especially challenging when large deformations occur. In this paper, we present a novel…

微分几何 · 数学 2013-10-08 Lam Ka Chun , Lok Ming Lui

Early diagnosis of prostate cancer significantly improves a patient's 5-year survival rate. Biopsy of small prostate cancers is improved with image-guided biopsy. MRI-ultrasound fusion-guided biopsy is sensitive to smaller tumors but is…

Nonlinear image registration continues to be a fundamentally important tool in medical image analysis. Diagnostic tasks, image-guided surgery and radiotherapy as well as motion analysis all rely heavily on accurate intra-patient alignment.…

计算机视觉与模式识别 · 计算机科学 2019-07-26 Mattias P. Heinrich

We propose a registration algorithm for 2D CT/MRI medical images with a new unsupervised end-to-end strategy using convolutional neural networks. The contributions of our algorithm are threefold: (1) We transplant traditional image…

计算机视觉与模式识别 · 计算机科学 2018-01-23 Siyuan Shan , Wen Yan , Xiaoqing Guo , Eric I-Chao Chang , Yubo Fan , Yan Xu
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