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Background: Depression is a major public health concern, affecting an estimated five percent of the global population. Early and accurate diagnosis is essential to initiate effective treatment, yet recognition remains challenging in many…

信号处理 · 电气工程与系统科学 2025-11-21 Jana Weber , Marcel Weber , Juan Miguel Lopez Alcaraz

Major depressive disorder (MDD) is a complex psychiatric disorder that affects the lives of hundreds of millions of individuals around the globe. Even today, researchers debate if morphological alterations in the brain are linked to MDD,…

定量方法 · 定量生物学 2025-01-27 Roberto Goya-Maldonado , Tracy Erwin-Grabner , Ling-Li Zeng , Christopher R. K. Ching , Andre Aleman , Alyssa R. Amod , Zeynep Basgoze , Francesco Benedetti , Bianca Besteher , Katharina Brosch , Robin Bülow , Romain Colle , Colm G. Connolly , Emmanuelle Corruble , Baptiste Couvy-Duchesne , Kathryn Cullen , Udo Dannlowski , Christopher G. Davey , Annemiek Dols , Jan Ernsting , Jennifer W. Evans , Lukas Fisch , Paola Fuentes-Claramonte , Ali Saffet Gonul , Ian H. Gotlib , Hans J. Grabe , Nynke A. Groenewold , Dominik Grotegerd , Tim Hahn , J. Paul Hamilton , Laura K. M. Han , Ben J. Harrison , Tiffany C. Ho , Neda Jahanshad , Alec J. Jamieson , Andriana Karuk , Tilo Kircher , Bonnie Klimes-Dougan , Sheri-Michelle Koopowitz , Thomas Lancaster , Ramona Leenings , Meng Li , David E. J. Linden , Frank P. MacMaster , David M. A. Mehler , Susanne Meinert , Elisa Melloni , Bryon A. Mueller , Benson Mwangi , Igor Nenadić , Amar Ojha , Yasumasa Okamoto , Mardien L. Oudega , Brenda W. J. H. Penninx , Sara Poletti , Edith Pomarol-Clotet , Maria J. Portella , Elena Pozzi , Joaquim Radua , Elena Rodríguez-Cano , Matthew D. Sacchet , Raymond Salvador , Anouk Schrantee , Kang Sim , Jair C. Soares , Aleix Solanes , Dan J. Stein , Frederike Stein , Aleks Stolicyn , Sophia I. Thomopoulos , Yara J. Toenders , Aslihan Uyar-Demir , Eduard Vieta , Yolanda Vives-Gilabert , Henry Völzke , Martin Walter , Heather C. Whalley , Sarah Whittle , Nils Winter , Katharina Wittfeld , Margaret J. Wright , Mon-Ju Wu , Tony T. Yang , Carlos Zarate , Dick J. Veltman , Lianne Schmaal , Paul M. Thompson

Early detection of depression from social media data offers a valuable opportunity for timely intervention. However, this task poses significant challenges, requiring both professional medical knowledge and the development of accurate and…

计算与语言 · 计算机科学 2025-03-20 Xiangyong Chen , Xiaochuan Lin

Dementia affects cognitive functions of adults, including memory, language, and behaviour. Standard diagnostic biomarkers such as MRI are costly, whilst neuropsychological tests suffer from sensitivity issues in detecting dementia onset.…

计算与语言 · 计算机科学 2023-12-27 Dimitris Gkoumas , Bo Wang , Adam Tsakalidis , Maria Wolters , Arkaitz Zubiaga , Matthew Purver , Maria Liakata

Speech production is a complex phenomenon, wherein the brain orchestrates a sequence of processes involving thought processing, motor planning, and the execution of articulatory movements. However, this intricate execution of various…

音频与语音处理 · 电气工程与系统科学 2024-06-06 Shakeel Ahmad Sheikh

Large Language Models (LLMs) have demonstrated remarkable success across diverse fields, establishing a powerful paradigm for complex information processing. This has inspired the integration of speech into LLM frameworks, often by…

音频与语音处理 · 电气工程与系统科学 2025-12-30 Xiangyu Zhang , Fuming Fang , Peng Gao , Bin Qin , Beena Ahmed , Julien Epps

With the widespread use of telemedicine services, automatic assessment of health conditions via telephone speech can significantly impact public health. This work summarizes our preliminary findings on automatic detection of respiratory…

音频与语音处理 · 电气工程与系统科学 2020-11-19 Meemnur Rashid , Kaisar Ahmed Alman , Khaled Hasan , John H. L. Hansen , Taufiq Hasan

Despite their success in speech processing, neural networks often operate as black boxes, prompting the question: what informs their decisions, and how can we interpret them? This work examines this issue in the context of lexical stress. A…

计算与语言 · 计算机科学 2026-02-13 Itai Allouche , Itay Asael , Rotem Rousso , Vered Dassa , Ann Bradlow , Seung-Eun Kim , Matthew Goldrick , Joseph Keshet

Speech is a scalable and non-invasive biomarker for early mental health screening. However, widely used depression datasets like DAIC-WOZ exhibit strong coupling between linguistic sentiment and diagnostic labels, encouraging models to…

计算与语言 · 计算机科学 2026-01-05 Yuxin Li , Xiangyu Zhang , Yifei Li , Zhiwei Guo , Haoyang Zhang , Eng Siong Chng , Cuntai Guan

Depression has affected millions of people worldwide and has become one of the most common mental disorders. Early mental disorder detection can reduce costs for public health agencies and prevent other major comorbidities. Additionally,…

计算与语言 · 计算机科学 2024-04-09 Giuliano Lorenzoni , Cristina Tavares , Nathalia Nascimento , Paulo Alencar , Donald Cowan

On the increase of major depressive disorders (MDD), many researchers paid attention to their recognition and treatment. Existing MDD recognition algorithms always use a single time-frequency domain method method, but the single…

神经元与认知 · 定量生物学 2021-11-03 Xiaofang Sun , Xiangwei Zheng , Yonghui Xu , Lizhen Cui , Bin Hu

Background Major depressive disorder (MDD) is a leading cause of global disability, yet current diagnostic approaches often rely on subjective assessments and lack the ability to integrate multimodal clinical information. Large language…

机器学习 · 计算机科学 2025-09-30 Yuyang Sha , Hongxin Pan , Gang Luo , Caijuan Shi , Jing Wang , Kefeng Li

In the field of text-independent speaker recognition, dynamic models that adapt along the time axis have been proposed to consider the phoneme-varying characteristics of speech. However, a detailed analysis of how dynamic models work…

音频与语音处理 · 电气工程与系统科学 2022-02-09 Seong-Hu Kim , Hyeonuk Nam , Yong-Hwa Park

Dementia is a group of irreversible, chronic, and progressive neurodegenerative disorders resulting in impaired memory, communication, and thought processes. In recent years, clinical research advances in brain aging have focused on the…

Background: Subtle changes in spontaneous language production are among the earliest indicators of cognitive decline. Identifying linguistically interpretable markers of dementia can support transparent and clinically grounded screening…

计算与语言 · 计算机科学 2026-02-12 Artsvik Avetisyan , Sachin Kumar

Automatic depression detection from doctor-patient conversations has gained momentum thanks to the availability of public corpora and advances in language modeling. However, interpretability remains limited: strong performance is often…

Alzheimer's Disease (AD) is an irreversible neurodegenerative disease affecting 50 million people worldwide. Low-cost, accurate identification of key markers of AD is crucial for timely diagnosis and intervention. Language impairment is one…

计算与语言 · 计算机科学 2025-05-27 Tingyu Mo , Jacqueline C. K. Lam , Victor O. K. Li , Lawrence Y. L. Cheung

Speech patterns have been identified as potential diagnostic markers for neuropsychiatric conditions. However, most studies only compare a single clinical group to healthy controls, whereas clinical practice often requires differentiating…

Neuropsychiatric disorders, such as Alzheimer's disease (AD), depression, and autism spectrum disorder (ASD), are characterized by linguistic and acoustic abnormalities, offering potential biomarkers for early detection. Despite the promise…

计算与语言 · 计算机科学 2025-12-25 Zhongren Dong , Haotian Guo , Weixiang Xu , Huan Zhao , Zixing Zhang