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Data analysis often encounters missing data, which can result in inaccurate conclusions, especially when it comes to ordinal variables. In trauma data, the Glasgow Coma Scale is useful for assessing the level of consciousness. This score is…

统计方法学 · 统计学 2025-07-01 Abdoulaye Dioni , Alexandre Bureau , Lynne Moore , Aida Eslami

Matching in observational studies faces complications when units enroll in treatment on a rolling basis. While each treated unit has a specific time of entry into the study, control units each have many possible comparison, or…

统计方法学 · 统计学 2024-07-16 Amanda K. Glazer , Samuel D. Pimentel

In observational studies, the observed association between an exposure and outcome of interest may be distorted by unobserved confounding. Causal sensitivity analysis can be used to assess the robustness of observed associations to…

统计方法学 · 统计学 2025-11-04 Rui Hu , Ted Westling

Observational studies often benefit from an abundance of observational units. This can lead to studies that -- while challenged by issues of internal validity -- have inferences derived from sample sizes substantially larger than randomized…

统计方法学 · 统计学 2020-08-24 Rachael C. Aikens , Dylan Greaves , Michael Baiocchi

Many major works in social science employ matching to make causal conclusions, but different matches on the same data may produce different treatment effect estimates, even when they achieve similar balance or minimize the same loss…

应用统计 · 统计学 2023-03-23 Marco Morucci , Cynthia Rudin

Confounding is a significant obstacle to unbiased estimation of causal effects from observational data. For settings with high-dimensional covariates -- such as text data, genomics, or the behavioral social sciences -- researchers have…

人工智能 · 计算机科学 2024-02-01 Katherine A. Keith , Sergey Feldman , David Jurgens , Jonathan Bragg , Rohit Bhattacharya

Bipartite experiments arise in various fields, in which the treatments are randomized over one set of units, while the outcomes are measured over another separate set of units. However, existing methods often rely on strong model…

统计方法学 · 统计学 2025-04-16 Sizhu Lu , Lei Shi , Yue Fang , Wenxin Zhang , Peng Ding

Causal inference from observational data can be viewed as a missing data problem arising from a hypothetical population-scale randomized trial matched to the observational study. This links a target trial protocol with a corresponding…

统计方法学 · 统计学 2022-07-27 Andrew Yiu , Edwin Fong , Stephen Walker , Chris Holmes

There exist many methods for sensitivity analysis readily available to the practitioner. While each seeks to help the modeler answer the same general question -- How do sources of uncertainty or changes in the model inputs relate to…

统计方法学 · 统计学 2025-06-16 Devin Francom , Abigael Nachtsheim

Causal approaches to fairness have seen substantial recent interest, both from the machine learning community and from wider parties interested in ethical prediction algorithms. In no small part, this has been due to the fact that causal…

机器学习 · 计算机科学 2019-08-17 Niki Kilbertus , Philip J. Ball , Matt J. Kusner , Adrian Weller , Ricardo Silva

When pre-processing observational data via matching, we seek to approximate each unit with maximally similar peers that had an alternative treatment status--essentially replicating a randomized block design. However, as one considers a…

计量经济学 · 经济学 2019-05-30 Gentry Johnson , Brian Quistorff , Matt Goldman

Matching mechanisms play a central role in operations management across diverse fields including education, healthcare, and online platforms. However, experimentally comparing a new matching algorithm against a status quo presents some…

统计方法学 · 统计学 2026-01-30 Chonghuan Wang

A data science task can be deemed as making sense of the data or testing a hypothesis about it. The conclusions inferred from data can greatly guide us to make informative decisions. Big data has enabled us to carry out countless prediction…

机器学习 · 计算机科学 2022-01-12 Wenhao Zhang , Ramin Ramezani , Arash Naeim

Non-linear mixed effects modeling and simulation (NLME M&S) is evaluated to be used for standardization with longitudinal data in presence of confounders. Standardization is a well-known method in causal inference to correct for confounding…

统计方法学 · 统计学 2024-05-01 Christian Bartels , Martina Scauda , Neva Coello , Thomas Dumortier , Bjoern Bornkamp , Giusi Moffa

In clinical settings, we often face the challenge of building prediction models based on small observational data sets. For example, such a data set might be from a medical center in a multi-center study. Differences between centers might…

Over the past two decades, considerable strides have been made in advancing neuroscientific techniques, yet challenges remain in attributing causality to observed associations. This review addresses a fundamental issue in observational…

其他定量生物学 · 定量生物学 2025-11-04 Eric W. Bridgeford , Brian S. Caffo , Maya B. Mathur , Russell A. Poldrack

Missing data is inevitable in longitudinal clinical trials. Conventionally, the missing at random assumption is assumed to handle missingness, which however is unverifiable empirically. Thus, sensitivity analysis is critically important to…

统计方法学 · 统计学 2022-03-18 Siyi Liu , Shu Yang , Yilong Zhang , Guanghan , Liu

Experimentation is widely utilized for causal inference and data-driven decision-making across disciplines. In an A/B experiment, for example, an online business randomizes two different treatments (e.g., website designs) to their customers…

统计方法学 · 统计学 2025-01-15 Wenxuan Guo , JungHo Lee , Panos Toulis

Causal inference is capable of estimating the treatment effect (i.e., the causal effect of treatment on the outcome) to benefit the decision making in various domains. One fundamental challenge in this research is that the treatment…

机器学习 · 计算机科学 2021-12-28 Qian Li , Zhichao Wang , Shaowu Liu , Gang Li , Guandong Xu

Weighting estimators based on propensity scores are widely used for causal estimation in a variety of contexts, such as observational studies, marginal structural models and interference. They enjoy appealing theoretical properties such as…

统计方法学 · 统计学 2021-10-06 Linbo Wang , Yuexia Zhang , Thomas S. Richardson , Xiao-Hua Zhou
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