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Age related macular degeneration (AMD) is one of the major causes for blindness in the elderly population. In this report, we propose deep learning based methods for retinal analysis using color fundus images for computer aided diagnosis of…

图像与视频处理 · 电气工程与系统科学 2020-09-04 Sharath M Shankaranarayana

Age-related macular degeneration (AMD) is a major cause of blindness in older adults, severely affecting vision and quality of life. Despite advances in understanding AMD, the molecular factors driving the severity of subretinal scarring…

基因组学 · 定量生物学 2024-09-10 Kuan Yan , Yue Zeng , Dai Shi , Ting Zhang , Dmytro Matsypura , Mark C. Gillies , Ling Zhu , Junbin Gao

Age-Related Macular Degeneration (AMD) is an asymptomatic retinal disease which may result in loss of vision. There is limited access to high-quality relevant retinal images and poor understanding of the features defining sub-classes of…

计算机视觉与模式识别 · 计算机科学 2019-02-13 Yi-Chieh Liu , Hao-Hsiang Yang , Chao-Han Huck Yang , Jia-Hong Huang , Meng Tian , Hiromasa Morikawa , Yi-Chang James Tsai , Jesper Tegner

This work aims to research an automatic method for detecting Age-related Macular Degeneration (AMD) lesions in RGB eye fundus images. For this, we align invasively obtained eye fundus contrast images (the "golden standard" diagnostic) to…

图像与视频处理 · 电气工程与系统科学 2021-10-19 Rokas Pečiulis , Mantas Lukoševičius , Algimantas Kriščiukaitis , Robertas Petrolis , Dovilė Buteikienė

Many diseases are classified based on human-defined rubrics that are prone to bias. Supervised neural networks can automate the grading of retinal fundus images, but require labor-intensive annotations and are restricted to the specific…

计算机视觉与模式识别 · 计算机科学 2020-10-26 Baladitya Yellapragada , Sascha Hornhauer , Kiersten Snyder , Stella Yu , Glenn Yiu

Age-related macular degeneration (AMD) is the leading cause of visual impairment among elderly in the world. Early detection of AMD is of great importance, as the vision loss caused by this disease is irreversible and permanent. Color…

We propose a method to predict severity of age related macular degeneration (AMD) from input optical coherence tomography (OCT) images. Although there is no standard clinical severity scale for AMD, we leverage deep learning (DL) based…

计算机视觉与模式识别 · 计算机科学 2019-07-09 Dwarikanath Mahapatra

Automatic diagnosis techniques have evolved to identify age-related macular degeneration (AMD) by employing single modality Fundus images or optical coherence tomography (OCT). To classify ocular diseases, fundus and OCT images are the most…

图像与视频处理 · 电气工程与系统科学 2024-09-04 Pragya Gupta , Subhamoy Mandal , Debashree Guha , Debjani Chakraborty

Age-related Macular Degeneration (AMD) is a leading cause of blindness. Although the Age-Related Eye Disease Study group previously developed a 9-step AMD severity scale for manual classification of AMD severity from color fundus images,…

机器学习 · 计算机科学 2018-12-04 Qingyu Chen , Yifan Peng , Tiarnan Keenan , Shazia Dharssi , Elvira Agron , Wai T. Wong , Emily Y. Chew , Zhiyong Lu

This paper tackles automated categorization of Age-related Macular Degeneration (AMD), a common macular disease among people over 50. Previous research efforts mainly focus on AMD categorization with a single-modal input, let it be a color…

计算机视觉与模式识别 · 计算机科学 2022-05-05 Weisen Wang , Xirong Li , Zhiyan Xu , Weihong Yu , Jianchun Zhao , Dayong Ding , Youxin Chen

By 2040, age-related macular degeneration (AMD) will affect approximately 288 million people worldwide. Identifying individuals at high risk of progression to late AMD, the sight-threatening stage, is critical for clinical actions,…

图像与视频处理 · 电气工程与系统科学 2020-07-21 Yifan Peng , Tiarnan D. Keenan , Qingyu Chen , Elvira Agrón , Alexis Allot , Wai T. Wong , Emily Y. Chew , Zhiyong Lu

Machine Learning (ML) is used to tackle various tasks, such as disease classification and prediction. The effectiveness of ML models relies heavily on having large amounts of complete data. However, healthcare data is often limited or…

Diseases are currently managed by grading systems, where patients are stratified by grading systems into stages that indicate patient risk and guide clinical management. However, these broad categories typically lack prognostic value, and…

In light of the expanding population, an automated framework of disease detection can assist doctors in the diagnosis of ocular diseases, yields accurate, stable, rapid outcomes, and improves the success rate of early detection. The work…

图像与视频处理 · 电气工程与系统科学 2023-08-31 Md. Aiyub Ali , Md. Shakhawat Hossain , Md. Kawar Hossain , Subhadra Soumi Sikder , Sharun Akter Khushbu , Mirajul Islam

Age-related Macular Degeneration (AMD) and Diabetic Macular Edema (DME) are the major causes of vision loss in developed countries. Alteration of retinal layer structure and appearance of exudate are the most significant signs of these…

图像与视频处理 · 电气工程与系统科学 2019-03-19 Elahe Mousavi , Rahele Kafieh , Hossein Rabbani

Age-related Macular Degeneration (AMD) is the predominant cause of blindness in developed countries, specially in elderly people. Moreover, its prevalence is increasing due to the global population ageing. In this scenario, early detection…

图像与视频处理 · 电气工程与系统科学 2022-05-24 José Morano , Álvaro S. Hervella , José Rouco , Jorge Novo , José I. Fernández-Vigo , Marcos Ortega

Age-related macular degeneration (AMD) is a degenerative disorder affecting the macula, a key area of the retina for visual acuity. Nowadays, it is the most frequent cause of blindness in developed countries. Although some promising…

图像与视频处理 · 电气工程与系统科学 2022-12-06 José Morano , Álvaro S. Hervella , José Rouco , Jorge Novo , José I. Fernández-Vigo , Marcos Ortega

Objective: The advent of Electronic Medical Records (EMR) with large electronic imaging databases along with advances in deep neural networks with machine learning has provided a unique opportunity to achieve milestones in automated image…

机器学习 · 统计学 2016-12-16 Cecilia S. Lee , Doug M. Baughman , Aaron Y. Lee

We propose a hybrid sequential deep learning model to predict the risk of AMD progression in non-exudative AMD eyes at multiple timepoints, starting from short-term progression (3-months) up to long-term progression (21-months). Proposed…

定量方法 · 定量生物学 2019-03-01 Imon Banerjee , Luis de Sisternes , Joelle Hallak , Theodore Leng , Aaron Osborne , Mary Durbin , Daniel Rubin

Identifying genes associated with diseases is crucial to understanding disease mechanisms and developing therapies. However, identification of individual genes associated with a disease often needs to be supplemented with clustering…

基因组学 · 定量生物学 2026-04-30 Brayan Gutierrez , Rinki Ratnapriya , Arko Barman
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