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Cellular appendages conferring motility, such as flagella or cilia, are known to synchronise their periodic beats. The origin of synchronisation is a combination of long-range hydrodynamic interactions with physical mechanisms allowing the…

生物物理 · 物理学 2021-04-21 Ivan Tanasijević , Eric Lauga

Synchronization of actively oscillating organelles such as cilia and flagella facilitates self-propulsion of cells and pumping fluid in low Reynolds number environments. To understand the key mechanism behind synchronization induced by…

软凝聚态物质 · 物理学 2015-05-20 Nariya Uchida , Ramin Golestanian

Organisms show a remarkable range of sizes, yet the dimensions of a single cell rarely exceed $100$ $\mu$m. While the physical and biological origins of this constraint remain poorly understood, exceptions to this rule give valuable…

生物物理 · 物理学 2015-05-20 Raymond E. Goldstein , Jan-Willem van de Meent

From the Golgi apparatus to endosomes, organelles in the endomembrane system exhibit complex and varied morphologies that are often related to their function. Such membrane-bound organelles operate far from equilibrium due to directed…

软凝聚态物质 · 物理学 2024-11-27 S. Alex Rautu , Richard G. Morris , Madan Rao

Liquid-liquid phase separation has emerged as a fundamental mechanism underlying intracellular organization, with evidence for it being reported in numerous different systems. However, there is a growing concern regarding the lack of…

软凝聚态物质 · 物理学 2022-12-09 Mrityunjay Kothari , Tal Cohen

Flowing blood displays a phenomenon called margination, in which leukocytes and platelets are preferentially found near blood vessel walls, while erythrocytes are depleted from these regions. Here margination is investigated using direct…

软凝聚态物质 · 物理学 2012-09-05 Amit Kumar , Michael D. Graham

Successful cell division requires a tight regulation of chromosome motion via the activity of molecular motors. Many of the key players at the origin of the forces generating the movement have been identified, but their spatial and temporal…

亚细胞过程 · 定量生物学 2009-11-11 Otger Campas , Pierre Sens

During cell division, the mitotic spindle moves dynamically through the cell to position the chromosomes and determine the ultimate spatial position of the two daughter cells. These movements have been attributed to the action of cortical…

亚细胞过程 · 定量生物学 2024-07-11 Dionn Hargreaves , Sarah Woolner , Oliver E. Jensen

The main motivation of this work is the quantitative prediction and description of particle manipulation (displacement across streamlines) in microfluidic flow. Much attention has been paid recently to placing particles in fast oscillatory…

流体动力学 · 物理学 2026-03-24 Xuchen Liu

Biological membranes are host to proteins and molecules which may form domain-like structures resulting in spatially-varying material properties. Vesicles with such heterogeneous membranes can exhibit intricate shapes at equilibrium and…

软凝聚态物质 · 物理学 2023-06-22 Prerna Gera , David Salac , Saverio E. Spagnolie

Cell crawling requires the generation of intracellular forces by the cytoskeleton and their transmission to an extracellular substrate through specific adhesion molecules. Crawling cells show many features of excitable systems, such as…

生物物理 · 物理学 2020-06-02 Pierre Sens

The cytoplasm and biomembranes in biological cells contain large numbers of proteins that cyclically change their shapes. They are molecular machines that can function as molecular motors or carry out many other tasks in the cell. We…

软凝聚态物质 · 物理学 2016-02-17 Alexander Mikhailov , Raymond Kapral

Macroscopic properties and shapes of biological tissues depend on the remodelling of cell-cell junctions at the microscopic scale. We propose a theoretical framework that couples a vertex model of solid confluent tissues with the dynamics…

软凝聚态物质 · 物理学 2020-12-02 Clement Zankoc , Matej Krajnc

We present new constrained and free-swimming experiments and simulations of a pair of pitching hydrofoils interacting in a minimal school. The hydrofoils have an out-of-phase synchronization and they are varied through in-line, staggered,…

流体动力学 · 物理学 2023-08-01 Pedro Costa Ormonde , Melike Kurt , Amin Mivehchi , Keith W. Moored

The journey of mammalian spermatozoa in nature is well-known to be reliant on their individual motility. Often swimming in crowded microenvironments, the progress of any single swimmer is likely dependent on their interactions with other…

流体动力学 · 物理学 2019-09-11 Benjamin J. Walker , Kenta Ishimoto , Eamonn A. Gaffney

Despite their importance in many biological, ecological and physical processes, microorganismal fluid flows under tight confinement have not been investigated experimentally. Strong screening of Stokelets in this geometry suggests that the…

生物物理 · 物理学 2019-12-18 Raphaël Jeanneret , Dmitri O. Pushkin , Marco Polin

A cellular bleb grows when a portion of the cell membrane detaches from the underlying cortex under the influence of a cytoplasmic pressure. We develop a quantitative model for the growth and dynamics of these objects in a simple…

生物物理 · 物理学 2015-06-05 Fong Yin Lim , Keng-Hwee Chiam , L. Mahadevan

Coordination of cytoplasmic flows on large scales in space and time are at the root of many cellular processes, including growth, migration or division. These flows are driven by organized contractions of the actomyosin cortex. In order to…

适应与自组织系统 · 物理学 2022-07-29 Busson Valentin , Saiseau Raphaël , Durand Marc

We have studied by Molecular Dynamics computer simulations the dynamics of water confined in ionic surfactants phases, ranging from well ordered lamellar structures to micelles at low and high water loading, respectively. We have analysed…

软凝聚态物质 · 物理学 2016-03-23 Samuel Hanot , Sandrine Lyonnard , Stefano Mossa