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Case-control designs are an important tool in contrasting the effects of well-defined treatments. In this paper, we reconsider classical concepts, assumptions and principles and explore when the results of case-control studies can be…

统计方法学 · 统计学 2021-05-06 Bas B. L. Penning de Vries , Rolf H. H. Groenwold

As research in causal inference has sought to address more complex scientific questions, the number of specialized estimands in the field has proliferated. Recognition that many of these estimands share a common linear form has generated…

统计方法学 · 统计学 2026-04-24 Salvador V. Balkus , Christian Testa , Nima S. Hejazi

Many benchmarks for automated causal inference evaluate a system's performance based on a single numerical output, such as an Average Treatment Effect (ATE). This approach conflates two distinct steps in causal analysis: identification -…

人工智能 · 计算机科学 2026-05-15 Ayush Sawarni , Jiyuan Tan , Vasilis Syrgkanis

Identifying covariates that modify treatment effects is a central problem in causal inference. Yet existing data-adaptive procedures do not provide finite-sample control over the expected number of false discoveries, risking spurious…

统计方法学 · 统计学 2026-05-12 Falco J. Bargagli-Stoffi , Omar Melikechi

We discuss causal inference for observational studies with possibly invalid instrumental variables. We propose a novel methodology called two-stage curvature identification (TSCI) by exploring the nonlinear treatment model with machine…

统计方法学 · 统计学 2024-01-08 Zijian Guo , Mengchu Zheng , Peter Bühlmann

Numerical simulations of models and theories that describe complex systems such as spin glasses are becoming increasingly important. Beyond fundamental research, these computational methods also find practical applications in fields like…

Predicting the effect of interventions with many possible variations, e.g., therapeutic content that affects mental health outcomes or an earnings call transcript that drives movement in share price, is useful across several domains.…

机器学习 · 计算机科学 2026-05-27 Nikita Dhawan , Arnav Paruthi , Andrew Kim , Lovedeep Gondara , Jekaterina Novikova , Chris J. Maddison

The research study of detecting multiple intents and filling slots is becoming more popular because of its relevance to complicated real-world situations. Recent advanced approaches, which are joint models based on graphs, might still face…

计算与语言 · 计算机科学 2023-12-12 Thinh Pham , Chi Tran , Dat Quoc Nguyen

Recent methods for improving LLM mathematical reasoning, whether through MCTS-based test-time search or causal graph-guided knowledge injection, cannot identify which concepts causally contribute to a correct answer, as the observed…

机器学习 · 计算机科学 2026-05-11 Tsuyoshi Okita

Consider the problem of estimating average treatment effects when a large number of covariates are used to adjust for possible confounding through outcome regression and propensity score models. The conventional approach of model building…

统计理论 · 数学 2018-01-31 Zhiqiang Tan

Simulation models often have parameters as input and return outputs to understand the behavior of complex systems. Calibration is the process of estimating the values of the parameters in a simulation model in light of observed data from…

统计方法学 · 统计学 2024-11-15 Özge Sürer

Causal inference is essential for developing and evaluating medical interventions, yet real-world medical datasets are often difficult to access due to regulatory barriers. This makes synthetic data a potentially valuable asset that enables…

The randomized controlled trial (RCT) is the gold standard for estimating the average treatment effect (ATE) of a medical intervention but requires 100s-1000s of subjects, making it expensive and difficult to implement. While a cross-over…

信号处理 · 电气工程与系统科学 2023-05-10 Sayeri Lala , Niraj K. Jha

As predictive algorithms grow in popularity, using the same dataset to both train and test a new model has become routine across research, policy, and industry. Sample-splitting attains valid inference on model properties by using separate…

计量经济学 · 经济学 2025-11-27 Bruno Fava

The paper reviews methods that seek to draw causal inference from observational data and demonstrates how they can be applied to empirical problems in engineering research. It presents a framework for causal identification based on the…

应用统计 · 统计学 2022-11-28 Daniel J Graham

This paper introduces a simple framework of counterfactual estimation for causal inference with time-series cross-sectional data, in which we estimate the average treatment effect on the treated by directly imputing counterfactual outcomes…

统计方法学 · 统计学 2022-08-16 Licheng Liu , Ye Wang , Yiqing Xu

In experimental design, we are given a large collection of vectors, each with a hidden response value that we assume derives from an underlying linear model, and we wish to pick a small subset of the vectors such that querying the…

机器学习 · 计算机科学 2019-02-05 Michał Dereziński , Kenneth L. Clarkson , Michael W. Mahoney , Manfred K. Warmuth

The synthetic control method (SCM) estimates causal effects in panel data with a single-treated unit by constructing a counterfactual outcome as a weighted combination of untreated control units that matches the pre-treatment trajectory. In…

机器学习 · 统计学 2026-05-13 Yuxin Wang , Dennis Frauen , Emil Javurek , Konstantin Hess , Yuchen Ma , Stefan Feuerriegel

Traditional statistical inference in cluster randomized trials typically invokes the asymptotic theory that requires the number of clusters to approach infinity. In this article, we propose an alternative conformal causal inference…

统计方法学 · 统计学 2024-10-03 Bingkai Wang , Fan Li , Mengxin Yu

In Software Product Line Engineering (SPLE) families of systems are designed, rather than developing the individual systems independently. Combinatorial Interaction Testing has proven to be effective for testing in the context of SPLE,…

软件工程 · 计算机科学 2013-12-06 Evelyn Nicole Haslinger , Roberto E. Lopez-Herrejon , Alexander Egyed