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Capturing how the Caenorhabditis elegans connectome structure gives rise to its neuron functionality remains unclear. It is through fiber symmetries found in its neuronal connectivity that synchronization of a group of neurons can be…

神经元与认知 · 定量生物学 2024-05-07 Bryant Avila , Pedro Augusto , Manuel Zimmer , Matteo Serafino , Hernán A. Makse

The connectome describes the complete set of synaptic contacts through which neurons communicate. While the architecture of the $\textit{C. elegans}$ connectome has been extensively characterized, much less is known about the organization…

神经元与认知 · 定量生物学 2025-09-18 Sophie Dvali , Caio Seguin , Richard Betzel , Andrew M. Leifer

The connectome, or the entire connectivity of a neural system represented by network, ranges various scales from synaptic connections between individual neurons to fibre tract connections between brain regions. Although the modularity they…

神经元与认知 · 定量生物学 2014-10-01 Jinseop S. Kim , Marcus Kaiser

The fundamental relationship between the mesoscopic structure of neuronal circuits and organismic functions they subserve is one of the major challenges in contemporary neuroscience. Formation of structurally connected modules of neurons…

神经元与认知 · 定量生物学 2024-01-12 Arsenii Onuchin , Alina Chernizova , Mikhail Lebedev , Kirill Polovnikov

The neural connectome of the nematode Caenorhabditis elegans has been completely mapped, yet in spite of being one of the smallest connectomes (302 neurons), the design principles that explain how the connectome structure determines its…

无序系统与神经网络 · 物理学 2020-01-08 Flaviano Morone , Hernan A. Makse

Probing the developing neural circuitry in Caenorhabditis elegans has enhanced our understanding of nervous systems. The C. elegans connectome, like those of other species, is characterized by a rich club of densely connected neurons…

神经元与认知 · 定量生物学 2021-08-26 Alec Helm , Ann S. Blevins , Danielle S. Bassett

We investigate how locomotory behavior is generated in the brain focusing on the paradigmatic connectome of nematode Caenorhabditis elegans (C. elegans) and on neuronal activity patterns that control forward locomotion. We map the neuronal…

适应与自组织系统 · 物理学 2020-06-17 Thomas Maertens , Eckehard Schöll , Jorge Ruiz , Philipp Hövel

Brain research has been driven by enquiry for principles of brain structure organization and its control mechanisms. The neuronal wiring map of C. elegans, the only complete connectome available till date, presents an incredible opportunity…

神经元与认知 · 定量生物学 2016-11-28 Rahul Badhwar , Ganesh Bagler

This research report introduces ElegansNet, a neural network that mimics real-world neuronal network circuitry, with the goal of better understanding the interplay between connectome topology and deep learning systems. The proposed approach…

神经与进化计算 · 计算机科学 2024-04-01 Francesco Bardozzo , Andrea Terlizzi , Pietro Liò , Roberto Tagliaferri

A major challenge in neuroscience is posed by the need for relating the emerging dynamical features of brain activity with the underlying modular structure of neural connections, hierarchically organized throughout several scales. The…

神经元与认知 · 定量生物学 2016-06-03 Pablo Villegas , Jorge Hidalgo , Paolo Moretti , Miguel A. Muñoz

Transient and equilibrium synchronizations in complex neuronal networks as a consequence of dynamics induced by having sources placed at specific neurons are investigated. The basic integrate-and-fire neuron is adopted, and the dynamics is…

神经元与认知 · 定量生物学 2008-02-18 Luciano da Fontoura Costa

There is renewed interest in modeling and understanding the nervous system of the nematode $\textit{Caenorhabditis elegans}$ ($\textit{C. elegans}$), as this small model system provides a path to bridge the gap between nervous system…

神经元与认知 · 定量生物学 2025-05-20 Quilee Simeon , Anshul Kashyap , Konrad P Kording , Edward S Boyden

Symmetries found through automorphisms or graph fibrations provide important insights in network analysis. Symmetries identify clusters of robust synchronization in the network which improves the understanding of the functionality of…

定量方法 · 定量生物学 2022-07-27 Ian Leifer , David Phillips , Francesco Sorrentino , Hernán A. Makse

Complex networks are the subject of fundamental interest from the scientific community at large. Several metrics have been introduced to characterize the structure of these networks, such as the degree distribution, degree correlation, path…

物理与社会 · 物理学 2019-01-14 Francesco Sorrentino , Abu Bakar Siddique , Louis M. Pecora

The large-scale structural ingredients of the brain and neural connectomes have been identified in recent years. These are, similar to the features found in many other real networks: the arrangement of brain regions into modules and the…

神经元与认知 · 定量生物学 2018-11-01 Gorka Zamora-López , Yuhan Chen , Gustavo Deco , Morten L. Kringelbach , Changsong Zhou

Partial synchronization plays a crucial role in the functioning of neuronal networks: selective, coordinated activation of neurons enables information processing that flexibly adapts to a changing computational context. Since the structure…

神经元与认知 · 定量生物学 2025-06-17 Daniil Radushev , Olesia Dogonasheva , Boris Gutkin , Denis Zakharov

We propose a data-driven approach to represent neuronal network dynamics as a Probabilistic Graphical Model (PGM). Our approach learns the PGM structure by employing dimension reduction to network response dynamics evoked by stimuli applied…

神经元与认知 · 定量生物学 2017-11-02 Hexuan Liu , Jimin Kim , Eli Shlizerman

Despite recent interest in reconstructing neuronal networks, complete wiring diagrams on the level of individual synapses remain scarce and the insights into function they can provide remain unclear. Even for Caenorhabditis elegans, whose…

神经元与认知 · 定量生物学 2011-02-07 Lav R. Varshney , Beth L. Chen , Eric Paniagua , David H. Hall , Dmitri B. Chklovskii

Neural systems show a modular and typically also a hierarchical organisation across different levels and across different species. Topology relates to function, but it is also influences dynamics as earlier studies showed its effect on…

神经元与认知 · 定量生物学 2014-05-15 Marcus Kaiser

We analyse the neural dynamics and its relation with the emergent behaviour of a robotic vehicle that is controlled by a neural network numerical simulation based on the nervous system of the nematode Caenorhabditis elegans. The robot…

神经元与认知 · 定量生物学 2020-11-19 Carlos E. Valencia Urbina , Sergio A. Cannas , Pablo M. Gleiser
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