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Parkinson's disease (PD) is a progressive neurodegenerative condition characterized by the death of dopaminergic neurons, leading to various movement disorder symptoms. Early diagnosis of PD is crucial to prevent adverse effects, yet…

Parkinson's disease (PD), a severe and progressive neurological illness, affects millions of individuals worldwide. For effective treatment and management of PD, an accurate and early diagnosis is crucial. This study presents a deep…

Diagnosis of Parkinson's disease (PD) is commonly based on medical observations and assessment of clinical signs, including the characterization of a variety of motor symptoms. However, traditional diagnostic approaches may suffer from…

Parkinson's disease (PD) is a progressive neurological disorder that impairs movement control, leading to symptoms such as tremors, stiffness, and bradykinesia. Many researchers analyzing handwriting data for PD detection typically rely on…

Parkinson's disease (PD), the second most common neurodegenerative disorder, is characterized by dopaminergic neuron loss and the accumulation of abnormal synuclein. PD presents both motor and non-motor symptoms that progressively impair…

Parkinsons disease (PD) is a debilitating motor system disorder characterized by progressive loss of movement, tremors, and speech slurring. PD is due to the loss of dopamine-producing brain cells, and symptoms only worsen over time, making…

Parkinson's Disease (PD) is the second most common neurodegenerative disorder. The existing assessment method for PD is usually the Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) to assess the severity of…

Adaptive deep brain stimulation (aDBS) has emerged as a promising treatment for Parkinson disease (PD). In aDBS, a surgically placed electrode sends dynamically altered stimuli to the brain based on neurophysiological feedback: an invasive…

Parkinsons Disease (PD) is a neurodegenerative disorder resulting in motor deficits due to advancing degeneration of dopaminergic neurons. PD patients report experiencing tremor, rigidity, visual impairment, bradykinesia, and several…

The paper presents a novel approach, based on deep learning, for diagnosis of Parkinson's disease through medical imaging. The approach includes analysis and use of the knowledge extracted by Deep Convolutional and Recurrent Neural Networks…

The stage and severity of Parkinson's disease (PD) is an important factor to consider for taking effective therapeutic decisions. Although the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) provides an…

Parkinson's disease (PD) is a neuro-degenerative disorder that affects movement, speech, and coordination. Timely diagnosis and treatment can improve the quality of life for PD patients. However, access to clinical diagnosis is limited in…

Decoding motor performance from brain signals offers promising avenues for adaptive deep brain stimulation (aDBS) for Parkinson's disease (PD). In a two-center cohort of 19 PD patients executing a drawing task, we decoded motor performance…

Parkinson's disease is easy to diagnose when it is advanced, but it is very difficult to diagnose in its early stages. Early diagnosis is essential to be able to treat the symptoms. It impacts on daily activities and reduces the quality of…

Parkinson's disease (PD) is a common neurological disorder characterized by gait impairment. PD has no cure, and an impediment to developing a treatment is the lack of any accepted method to predict disease progression rate. The primary aim…

Parkinson's disease (PD) is a highly heterogeneous disease, including which motor symptoms are dominating. Imaging biomarkers that support subtype stratification could also improve biological understanding and study design, and enable…

Parkinson's disease (PD) is a prevalent neurodegenerative disorder known for its impact on motor neurons, causing symptoms like tremors, stiffness, and gait difficulties. This study explores the potential of vocal feature alterations in PD…

We present a nonlinear data-driven Model Predictive Control (MPC) algorithm for deep brain stimulation (DBS) for the treatment of Parkinson's disease (PD). Although DBS is typically implemented in open-loop, closed-loop DBS (CLDBS) uses the…

We present an artificial intelligence system to remotely assess the motor performance of individuals with Parkinson's disease (PD). Participants performed a motor task (i.e., tapping fingers) in front of a webcam, and data from 250 global…

In this paper, we analyze 48 signals of rest tremor velocity related to 12 distinct subjects affected by Parkinson's disease. The subjects belong to two different groups, formed by four and eight subjects with, respectively, high- and…