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A major bottleneck in developing sustainable processes and materials is a lack of property data. Recently, machine learning approaches have vastly improved previous methods for predicting molecular properties. However, these machine…

化学物理 · 物理学 2023-09-25 Benedikt Winter , Philipp Rehner , Timm Esper , Johannes Schilling , André Bardow

Over the last decades, many prognostic models based on artificial intelligence techniques have been used to provide detailed predictions in healthcare. Unfortunately, the real-world observational data used to train and validate these models…

机器学习 · 计算机科学 2023-11-21 Alice Bernasconi , Alessio Zanga , Peter J. F. Lucas , Marco Scutari , Fabio Stella

The rapidly emerging field of deep learning-based computational pathology has shown promising results in utilizing whole slide images (WSIs) to objectively prognosticate cancer patients. However, most prognostic methods are currently…

计算机视觉与模式识别 · 计算机科学 2023-11-21 Mingxin Liu , Yunzan Liu , Hui Cui , Chunquan Li , Jiquan Ma

Next-generation sequencing technologies allow the measurement of somatic mutations in a large number of patients from the same cancer type. One of the main goals in analyzing these mutations is the identification of mutations associated…

定量方法 · 定量生物学 2016-09-13 Tommy Hansen , Fabio Vandin

Diabetes mellitus affects over 537 million adults worldwide and remains a major challenge in preventive healthcare. Existing machine-learning studies primarily formulate diabetes prediction as a binary classification problem, while…

机器学习 · 计算机科学 2026-05-14 Vishal Pandey , Ruzina Haque Laskar , Rishav Tewari

Effectively medication recommendation with complex multimorbidity conditions is a critical task in healthcare. Most existing works predicted medications based on longitudinal records, which assumed the information transmitted patterns of…

机器学习 · 计算机科学 2023-09-13 Sicen Liu , Xiaolong Wang , JIngcheng Du , Yongshuai Hou , Xianbing Zhao , Hui Xu , Hui Wang , Yang Xiang , Buzhou Tang

The patterns of different financial data sources vary substantially, and accordingly, investors exhibit heterogeneous cognition behavior in information processing. To capture different patterns, we propose a novel approach called the…

计算工程、金融与科学 · 计算机科学 2025-12-17 Ruize Gao , Mei Yang , Yu Wang , Shaoze Cui

Multiple instance learning (MIL) is the dominant framework for whole-slide image analysis in computational pathology, typically combining a frozen patch encoder, a projection layer, and a slide-level aggregator. While encoders and…

定量方法 · 定量生物学 2026-05-19 Yucheng Xing , Pei Liu , Jingying Ma , Ruping Hong , Jiangdong Qiu , Tianyu Liu , Kai He , Ling Huang , Mengling Feng

This work introduces a novel framework for brain tumor segmentation leveraging pre-trained GANs and Unet architectures. By combining a global anomaly detection module with a refined mask generation network, the proposed model accurately…

图像与视频处理 · 电气工程与系统科学 2025-06-27 Qifei Cui , Xinyu Lu

This work proposes a unified framework for portfolio allocation, covering both asset selection and optimization, based on a multiple-hypothesis predict-then-optimize approach. The portfolio is modeled as a structured ensemble, where each…

投资组合管理 · 定量金融 2025-11-19 Alejandro Rodriguez Dominguez , Muhammad Shahzad , Xia Hong

Late diagnosis and high costs are key factors that negatively impact the care of cancer patients worldwide. Although the availability of biological markers for the diagnosis of cancer type is increasing, costs and reliability of tests…

机器学习 · 计算机科学 2019-08-20 Sterling Ramroach , Melford John , Ajay Joshi

Metal Additive Manufacturing (MAM) has reshaped the manufacturing industry, offering benefits like intricate design, minimal waste, rapid prototyping, material versatility, and customized solutions. However, its full industry adoption faces…

机器学习 · 计算机科学 2024-01-12 Ahmed Shoyeb Raihan , Hamed Khosravi , Tanveer Hossain Bhuiyan , Imtiaz Ahmed

The rapid integration of machine learning methodologies in healthcare has ignited innovative strategies for disease prediction, particularly with the vast repositories of Electronic Health Records (EHR) data. This article delves into the…

机器学习 · 计算机科学 2024-08-07 D. Dhinakaran , S. Edwin Raja , M. Thiyagarajan , J. Jeno Jasmine , P. Raghavan

Multi-sourced datasets are common in studies of variable interactions, for example, individual-level fMRI integration, cross-domain recommendation, etc, where each source induces a related but distinct dependency structure. Joint learning…

统计方法学 · 统计学 2025-12-08 Shixiang Liu , Yanhang Zhang , Zhifan Li , Jianxin Yin

Positive selection drives the emergence of adaptive mutations in Mycobacterium tuberculosis, shaping drug resistance, transmissibility, and virulence. Phylogenetic trees capture evolutionary relationships among isolates and provide a…

种群与进化 · 定量生物学 2025-10-13 Linfeng Wang , Susana Campino , Taane G. Clark , Jody E. Phelan

Stroke is a major cause of death and permanent impairment, making it a major worldwide health concern. For prompt intervention and successful preventative tactics, early risk assessment is essential. To address this challenge, we used…

计算机视觉与模式识别 · 计算机科学 2025-12-02 A S M Ahsanul Sarkar Akib , Raduana Khawla , Abdul Hasib

As machine learning (ML) methods continue to be applied to a broad scope of problems in the physical sciences, uncertainty quantification is becoming correspondingly more important for their robust application. Uncertainty aware machine…

Recent advancements in Spatial Transcriptomics (ST) technology have facilitated detailed gene expression analysis within tissue contexts. However, the high costs and methodological limitations of ST necessitate a more robust predictive…

计算机视觉与模式识别 · 计算机科学 2024-04-26 Youngmin Chung , Ji Hun Ha , Kyeong Chan Im , Joo Sang Lee

In our study, we demonstrate the synergy effect between convolutional neural networks and the multiplicity of SMILES. The model we propose, the so-called Convolutional Neural Fingerprint (CNF) model, reaches the accuracy of traditional…

机器学习 · 计算机科学 2018-12-12 Talia B. Kimber , Sebastian Engelke , Igor V. Tetko , Eric Bruno , Guillaume Godin

Benefiting from the advancements in deep learning, various genomic analytical techniques, such as survival analysis, classification of tumors and their subtypes, and exploration of specific pathways, have significantly enhanced our…

机器学习 · 计算机科学 2023-12-19 Xiangyu Meng , Xue Li , Qing Yang , Huanhuan Dai , Lian Qiao , Hongzhen Ding , Long Hao , Xun Wang
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