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Multiple Sclerosis (MS) is a disorder that usually appears in adults in their thirties. It has a prevalence that ranges between 2 and 150 per 100 000. Epidemiological studies of MS have provided hints on possible causes for the disease…

亚细胞过程 · 定量生物学 2013-08-23 Laura Facchini , Alberto Bellin , Eleuterio F. Toro

This paper presents an approach to estimating the health effects of an environmental hazard. The approach is general in nature, but is applied here to the case of air pollution. It uses a computer model involving ambient pollution and…

应用统计 · 统计学 2007-11-01 Gavin Shaddick , Duncan Lee , James V. Zidek , Ruth Salway

Background: An early diagnosis together with an accurate disease progression monitoring of multiple sclerosis is an important component of successful disease management. Prior studies have established that multiple sclerosis is correlated…

音频与语音处理 · 电气工程与系统科学 2021-09-28 Emil Svoboda , Tomáš Bořil , Jan Rusz , Tereza Tykalová , Dana Horáková , Charles R. G. Guttman , Krastan B. Blagoev , Hiroto Hatabu , Vlad I. Valtchinov

Diabetes is a prevalent chronic disease with significant health and economic burdens worldwide. Early prediction and diagnosis can aid in effective management and prevention of complications. This study explores the use of machine learning…

机器学习 · 计算机科学 2025-03-07 Bruce Nguyen , Yan Zhang

Multiple Sclerosis (MS) is a chronic neurological condition characterized by the development of lesions in the white matter of the brain. T2-fluid attenuated inversion recovery (FLAIR) brain magnetic resonance imaging (MRI) provides…

图像与视频处理 · 电气工程与系统科学 2022-09-01 Jueqi Wang , Derek Berger , Erin Mazerolle , Jean-Alexis Delamer , Jacob Levman

The spread of PM2.5 pollutants that endanger health is difficult to predict because it involves many atmospheric variables. These micron particles can spread rapidly from their source to residential areas, increasing the risk of respiratory…

机器学习 · 计算机科学 2021-01-18 Hsing-Chung Chen , Karisma Trinanda Putra , Jerry Chun-WeiLin

The impact of wildfire smoke on air quality is a growing concern, contributing to air pollution through a complex mixture of chemical species with important implications for public health. While previous studies have primarily focused on…

统计方法学 · 统计学 2026-02-10 Dafne Zorzetto , Jenna Landy , Corwin Zigler , Giovanni Parmigiani , Roberta De Vito

Estimating the joint effect of a multivariate, continuous exposure is crucial, particularly in environmental health where interest lies in simultaneously evaluating the impact of multiple environmental pollutants on health. We develop novel…

统计方法学 · 统计学 2025-01-06 Heejun Shin , Antonio Linero , Michelle Audirac , Kezia Irene , Danielle Braun , Joseph Antonelli

Unmeasured spatial confounding complicates exposure effect estimation in environmental health studies. This problem is exacerbated in studies with multiple health outcomes and environmental exposure variables, as the source and magnitude of…

Introduction: Multiple Sclerosis (MS) is a chronic disease that affects millions of people across the globe. MS can critically affect different organs of the central nervous system such as the eyes, the spinal cord, and the brain.…

图像与视频处理 · 电气工程与系统科学 2023-02-21 Atif Shah , Maged S. Al-Shaibani , Moataz Ahmad , Reem Bunyan

A schizophrenia relapse has severe consequences for a patient's health, work, and sometimes even life safety. If an oncoming relapse can be predicted on time, for example by detecting early behavioral changes in patients, then interventions…

Predictive models allow subject-specific inference when analyzing disease related alterations in neuroimaging data. Given a subject's data, inference can be made at two levels: global, i.e. identifiying condition presence for the subject,…

计算机视觉与模式识别 · 计算机科学 2018-07-18 Ender Konukoglu , Ben Glocker

Background: Reliable prediction of clinical progression over time can improve the outcomes of depression. Little work has been done integrating various risk factors for depression, to determine the combinations of factors with the greatest…

机器学习 · 统计学 2023-07-06 Runa Bhaumik , Jonathan Stange

Multiple Sclerosis (MS) is a severe neurological disease characterized by inflammatory lesions in the central nervous system. Hence, predicting inflammatory disease activity is crucial for disease assessment and treatment. However, MS…

图像与视频处理 · 电气工程与系统科学 2023-09-01 Chinmay Prabhakar , Hongwei Bran Li , Johannes C. Paetzold , Timo Loehr , Chen Niu , Mark Mühlau , Daniel Rueckert , Benedikt Wiestler , Bjoern Menze

Magnetic Resonance Spectroscopy (MRS) is a noninvasive tool to reveal metabolic information. One challenge of 1H-MRS is the low Signal-Noise Ratio (SNR). To improve the SNR, a typical approach is to perform Signal Averaging (SA) with M…

Spatio-temporal prediction of levels of an environmental exposure is an important problem in environmental epidemiology. Our work is motivated by multiple studies on the spatio-temporal distribution of mobile source, or traffic related,…

应用统计 · 统计学 2014-11-14 Nikolay Bliznyuk , Christopher J. Paciorek , Joel Schwartz , Brent Coull

Laboratory experiments have shown that cardiovascular diseases are positively correlated to the concentration of ambient air pollutants, such as SO2, NO2, PM10, etc. It has also been repeatedly reported in many countries that increased…

应用统计 · 统计学 2013-08-08 Menghui Li , Dasheng Luo , Chenghua Cao , Xiaochuan Pan , Qixin Wang

Motivated by loss of control risks from misaligned AI systems, we develop and apply methods for measuring language models' propensity for unsanctioned behaviour. We contribute three methodological improvements: analysing effects of changes…

人工智能 · 计算机科学 2026-04-24 Olli Järviniemi , Oliver Makins , Jacob Merizian , Robert Kirk , Ben Millwood

Environmental hazards place certain individuals at disproportionately higher risks. As these hazards increasingly endanger human health, precise identification of the most vulnerable population subgroups is critical for public health.…

机器学习 · 计算机科学 2024-09-23 Jong Woo Nam , Eun Young Choi , Jennifer A. Ailshire , Yao-Yi Chiang

System outputs such as eigenfrequencies or strain data, often used in structural health monitoring (SHM), not only react to damage but also depend on environmental conditions. When trying to correct for these confounding effects, it is…

应用统计 · 统计学 2026-03-25 Lizzie Neumann , Philipp Wittenberg , Jan Gertheiss