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Recent advances in whole-slide image (WSI) scanners and computational capabilities have significantly propelled the application of artificial intelligence in histopathology slide analysis. While these strides are promising, current…

计算机视觉与模式识别 · 计算机科学 2023-11-15 Weiyi Wu , Chongyang Gao , Joseph DiPalma , Soroush Vosoughi , Saeed Hassanpour

Deep neural networks are increasingly applied in automated histopathology. Yet, whole-slide images (WSIs) are often acquired at gigapixel sizes, rendering them computationally infeasible to analyze entirely at high resolution. Diagnostic…

图像与视频处理 · 电气工程与系统科学 2026-02-10 Tarun G , Naman Malpani , Gugan Thoppe , Sridharan Devarajan

In modern cancer diagnostics, Whole Slide Imaging (WSI) is widely used to digitize tissue specimens for detailed, high-resolution examination; however, other diagnostic approaches, such as liquid biopsy and molecular testing, are also…

计算机视觉与模式识别 · 计算机科学 2025-07-02 Seyed Kahaki , Alexander R. Webber , Ghada Zamzmi , Adarsh Subbaswamy , Rucha Deshpande , Aldo Badano

Immunohistochemistry (IHC) is essential for assessing specific immune biomarkers like Human Epidermal growth-factor Receptor 2 (HER2) in breast cancer. However, the traditional protocols of obtaining IHC stains are resource-intensive,…

图像与视频处理 · 电气工程与系统科学 2026-04-10 Aasim Bin Saleem , Amr Ahmed , Ardhendu Behera , Hafeezullah Amin , Iman Yi Liao , Mahmoud Khattab , Pan Jia Wern , Haslina Makmur

The development of generative models in the past decade has allowed for hyperrealistic data synthesis. While potentially beneficial, this synthetic data generation process has been relatively underexplored in cancer histopathology. One…

图像与视频处理 · 电气工程与系统科学 2024-12-10 Aakash Madhav Rao , Debayan Gupta

Capsule endoscopy has enabled minimally invasive gastrointestinal imaging, but its clinical utility is limited by the inherently low resolution of captured images due to hardware, power, and transmission constraints. This limitation hampers…

图像与视频处理 · 电气工程与系统科学 2025-12-30 Haozhe Jia

Accurate classification of haematological cells is critical for diagnosing blood disorders, but presents significant challenges for machine automation owing to the complexity of cell morphology, heterogeneities of biological, pathological,…

Histopathology digital scans are large-size images that contain valuable information at the pixel level. Content-based comparison of these images is a challenging task. This study proposes a content-based similarity measure for…

图像与视频处理 · 电气工程与系统科学 2021-07-30 Mehdi Afshari , H. R. Tizhoosh

Histo-genomic multi-modal methods have recently emerged as a powerful paradigm, demonstrating significant potential for improving cancer prognosis. However, genome sequencing, unlike histopathology imaging, is still not widely accessible in…

图像与视频处理 · 电气工程与系统科学 2024-03-19 Zhikang Wang , Yumeng Zhang , Yingxue Xu , Seiya Imoto , Hao Chen , Jiangning Song

The deep neural network is a research hotspot for histopathological image analysis, which can improve the efficiency and accuracy of diagnosis for pathologists or be used for disease screening. The whole slide pathological image can reach…

图像与视频处理 · 电气工程与系统科学 2022-05-09 Tingting Zheng , Weixing chen , Shuqin Li , Hao Quan , Qun Bai , Tianhang Nan , Song Zheng , Xinghua Gao , Yue Zhao , Xiaoyu Cui

Ensuring diagnostic performance of AI models before clinical use is key to the safe and successful adoption of these technologies. Studies reporting AI applied to digital pathology images for diagnostic purposes have rapidly increased in…

Image restoration (IR) has been an indispensable and challenging task in the low-level vision field, which strives to improve the subjective quality of images distorted by various forms of degradation. Recently, the diffusion model has…

计算机视觉与模式识别 · 计算机科学 2025-12-09 Xin Li , Yulin Ren , Xin Jin , Cuiling Lan , Xingrui Wang , Wenjun Zeng , Xinchao Wang , Zhibo Chen

Visual microscopic study of diseased tissue by pathologists has been the cornerstone for cancer diagnosis and prognostication for more than a century. Recently, deep learning methods have made significant advances in the analysis and…

图像与视频处理 · 电气工程与系统科学 2022-09-30 Puria Azadi Moghadam , Sanne Van Dalen , Karina C. Martin , Jochen Lennerz , Stephen Yip , Hossein Farahani , Ali Bashashati

Diffusion models have emerged as the leading approach for image synthesis, demonstrating exceptional photorealism and diversity. However, training diffusion models at high resolutions remains computationally prohibitive, and existing…

计算机视觉与模式识别 · 计算机科学 2025-06-26 Tobias Vontobel , Seyedmorteza Sadat , Farnood Salehi , Romann M. Weber

Diffusion Generative Models (DGM) have rapidly surfaced as emerging topics in the field of computer vision, garnering significant interest across a wide array of deep learning applications. Despite their high computational demand, these…

图像与视频处理 · 电气工程与系统科学 2024-11-26 Denisha Thakkar , Vincent Quoc-Huy Trinh , Sonal Varma , Samira Ebrahimi Kahou , Hassan Rivaz , Mahdi S. Hosseini

We present PathoSyn, a unified generative framework for Magnetic Resonance Imaging (MRI) image synthesis that reformulates imaging-pathology as a disentangled additive deviation on a stable anatomical manifold. Current generative models…

计算机视觉与模式识别 · 计算机科学 2026-01-14 Jian Wang , Sixing Rong , Jiarui Xing , Yuling Xu , Weide Liu

Recent deep learning-based image completion methods, including both inpainting and outpainting, have demonstrated promising results in restoring corrupted images by effectively filling various missing regions. Among these, Generative…

计算机视觉与模式识别 · 计算机科学 2025-02-11 Yike Zhang , Eduardo Davalos , Jack Noble

Histopathology plays a pivotal role in medical diagnostics. In contrast to preparing permanent sections for histopathology, a time-consuming process, preparing frozen sections is significantly faster and can be performed during surgery,…

图像与视频处理 · 电气工程与系统科学 2023-10-18 Elad Yoshai , Gil Goldinger , Miki Haifler , Natan T. Shaked

Histopathology whole slide images (WSIs) are being widely used to develop deep learning-based diagnostic solutions, especially for precision oncology. Most of these diagnostic softwares are vulnerable to biases and impurities in the…

图像与视频处理 · 电气工程与系统科学 2024-10-01 Abhijeet Patil , Harsh Diwakar , Jay Sawant , Nikhil Cherian Kurian , Subhash Yadav , Swapnil Rane , Tripti Bameta , Amit Sethi

Virtual staining of histopathology images (e.g., H&E-IHC) is an emerging tool in digital pathology, enabling faster and cheaper workflows by synthesizing target stains from routinely acquired slides. Yet, the quality of virtual staining…