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We propose a novel method for multiple clustering that assumes a co-clustering structure (partitions in both rows and columns of the data matrix) in each view. The new method is applicable to high-dimensional data. It is based on a…

Neuroimaging studies produce gigabytes of spatio-temporal data for a small number of participants and stimuli. Rarely do researchers attempt to model and examine how individual participants vary from each other -- a question that should be…

Regional data analysis is concerned with the analysis and modeling of measurements that are spatially separated by specifically accounting for typical features of such data. Namely, measurements in close proximity tend to be more similar…

统计方法学 · 统计学 2023-08-15 Christoph Muehlmann , François Bachoc , Klaus Nordhausen

Recent advances in deep learning have made it possible to predict phenotypic measures directly from functional magnetic resonance imaging (fMRI) brain volumes, sparking significant interest in the neuroimaging community. However, existing…

计算机视觉与模式识别 · 计算机科学 2025-07-01 Arunkumar Kannan , Martin A. Lindquist , Brian Caffo

In this paper, we develop a method for unsupervised clustering of two-way (matrix) data by combining two recent innovations from different fields: the Sparse Subspace Clustering (SSC) algorithm [10], which groups points coming from a union…

机器学习 · 计算机科学 2015-02-24 Eric Kernfeld , Shuchin Aeron , Misha Kilmer

Motivation: Modelling methods that find structure in data are necessary with the current large volumes of genomic data, and there have been various efforts to find subsets of genes exhibiting consistent patterns over subsets of treatments.…

机器学习 · 计算机科学 2016-09-15 Kerstin Bunte , Eemeli Leppäaho , Inka Saarinen , Samuel Kaski

There is a growing interest in the estimation of the number of unseen features, mostly driven by biological applications. A recent work brought out a peculiar property of the popular completely random measures (CRMs) as prior models in…

统计方法学 · 统计学 2022-02-22 Federico Camerlenghi , Stefano Favaro , Lorenzo Masoero , Tamara Broderick

Geometric information in the normalized digital surface models (nDSM) is highly correlated with the semantic class of the land cover. Exploiting two modalities (RGB and nDSM (height)) jointly has great potential to improve the segmentation…

计算机视觉与模式识别 · 计算机科学 2023-05-25 Zhitong Xiong , Sining Chen , Yi Wang , Lichao Mou , Xiao Xiang Zhu

We consider the problem of clustering data points in high dimensions, i.e. when the number of data points may be much smaller than the number of dimensions. Specifically, we consider a Gaussian mixture model (GMM) with non-spherical…

统计理论 · 数学 2014-06-10 Martin Azizyan , Aarti Singh , Larry Wasserman

The growing use of neuroimaging technologies generates a massive amount of biomedical data that exhibit high dimensionality. Tensor-based analysis of brain imaging data has been proved quite effective in exploiting their multiway nature.…

数值分析 · 计算机科学 2016-07-21 Christos Chatzichristos , Eleftherios Kofidis , Giannis Kopsinis , Sergios Theodoridis

Spatial transcriptomics technologies enable the measurement of gene expression with spatial context, providing opportunities to understand how gene regulatory networks vary across tissue regions. However, existing graphical models focus…

统计方法学 · 统计学 2025-12-15 Trisha Dawn , Yang Ni

This article introduces a nonparametric approach to spectral analysis of a high-dimensional multivariate nonstationary time series. The procedure is based on a novel frequency-domain factor model that provides a flexible yet parsimonious…

统计方法学 · 统计学 2019-10-29 Zeda Li , Ori Rosen , Fabio Ferrarelli , Robert T. Krafty

Spatially resolved transcriptomics represents a significant advancement in single-cell analysis by offering both gene expression data and their corresponding physical locations. However, this high degree of spatial resolution entails a…

基因组学 · 定量生物学 2024-03-19 Xiaoyu Li , Wenwen Min , Shunfang Wang , Changmiao Wang , Taosheng Xu

Non-gaussian spatial data are very common in many disciplines. For instance, count data are common in disease mapping, and binary data are common in ecology. When fitting spatial regressions for such data, one needs to account for…

统计方法学 · 统计学 2010-12-01 John Hughes , Murali Haran

Gaussian processes are widely used for the analysis of spatial data due to their nonparametric flexibility and ability to quantify uncertainty, and recently developed scalable approximations have facilitated application to massive datasets.…

统计方法学 · 统计学 2021-10-13 F. William Townes , Barbara E. Engelhardt

In many real life problems, objects are described by large number of binary features. For instance, documents are characterized by presence or absence of certain keywords; cancer patients are characterized by presence or absence of certain…

应用统计 · 统计学 2016-03-09 Tapesh Santra

Nonnegative matrix factorization (NMF) is a powerful tool in data exploratory analysis by discovering the hidden features and part-based patterns from high-dimensional data. NMF and its variants have been successfully applied into diverse…

计算机视觉与模式识别 · 计算机科学 2017-07-27 Lihua Zhang , Shihua Zhang

We introduce deep Markov spatio-temporal factorization (DMSTF), a generative model for dynamical analysis of spatio-temporal data. Like other factor analysis methods, DMSTF approximates high dimensional data by a product between time…

To address the dual challenges of the curse of dimensionality and the difficulty in separating intra-cluster and inter-cluster structures in high-dimensional manifold embedding, we proposes an Adaptive Multi-Scale Manifold Embedding (AMSME)…

机器学习 · 计算机科学 2025-03-20 Tianhao Ni , Bingjie Li , Zhigang Yao

Somatic mutations, or alterations in DNA of a somatic cell, are key markers of cancer. In recent years, mutational signature analysis has become a prominent field of study within cancer research, commonly with Nonnegative Matrix…

定量方法 · 定量生物学 2025-07-01 Iris Lang , Jenna Landy , Giovanni Parmigiani