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The fundamental non-Hermitian nature of the forms of coupled-cluster (CC) theory widely used in quantum chemistry has usually been viewed as a negative, but the present letter shows how this can be used to advantage. Specifically, the…

The capacity to predict and control bioprocesses is perhaps one of the most important objectives of biotechnology. Computational simulation is an established methodology for the design and optimization of bioprocesses, where the finite…

计算工程、金融与科学 · 计算机科学 2015-08-12 R. C. Martins , N. Fachada

Given stabilizer operations and the ability to repeatedly prepare a single-qubit mixed state rho, can we do universal quantum computation? As motivation for this question, "magic state" distillation procedures can reduce the general…

量子物理 · 物理学 2007-05-23 Ben W. Reichardt

We introduce a general scheme for sequential one-way quantum computation where static systems with long-living quantum coherence (memories) interact with moving systems that may possess very short coherence times. Both the generation of the…

量子物理 · 物理学 2015-05-27 Augusto J. Roncaglia , Leandro Aolita , Alessandro Ferraro , Antonio Acin

A novel computing model, called \emph{Probe Machine}, is proposed in this paper. Different from Turing Machine, Probe Machine is a fully-parallel computing model in the sense that it can simultaneously process multiple pairs of data, rather…

计算复杂性 · 计算机科学 2016-03-01 Jin Xu

We prove classical simulation hardness, under the generalized $\mathsf{P}\neq\mathsf{NP}$ conjecture, for quantum circuit families with applications in near-term chemical ground state estimation. The proof exploits a connection to particle…

量子物理 · 物理学 2026-02-06 Oskar Leimkuhler , K. Birgitta Whaley

The field of quantum algorithms is vibrant. Still, there is currently a lack of programming languages for describing quantum computation on a practical scale, i.e., not just at the level of toy problems. We address this issue by introducing…

编程语言 · 计算机科学 2013-07-08 Alexander S. Green , Peter LeFanu Lumsdaine , Neil J. Ross , Peter Selinger , Benoît Valiron

Future quantum computers capable of solving relevant problems will require a large number of qubits that can be operated reliably. However, the requirements of having a large qubit count and operating with high-fidelity are typically…

A quantum compiling algorithm is an algorithm for decomposing ("compiling") an arbitrary unitary matrix into a sequence of elementary operations (SEO). Suppose $U_{in}$ is an $\nb$-bit unstructured unitary matrix (a unitary matrix with no…

量子物理 · 物理学 2007-05-23 Robert R. Tucci

Expanding upon the widely recognized notion of mathematical universality in Turing machines, a concept of thermodynamic universality in Turing machines is introduced. Under the physical Church-Turing thesis, the existence of a…

计算复杂性 · 计算机科学 2023-08-07 Jihai Zhu

Compiling quantum circuits to account for hardware restrictions is an essential part of the quantum computing stack. Circuit compilation allows us to adapt algorithm descriptions into a sequence of operations supported by real quantum…

量子物理 · 物理学 2025-10-14 Alejandro Villoria , Henning Basold , Alfons Laarman

Large Language Models (LLMs) have demonstrated remarkable potential in scientific research, particularly in chemistry-related tasks such as molecular design, reaction prediction, and property estimation. While tool-augmented LLMs have been…

计算工程、金融与科学 · 计算机科学 2025-02-21 Zhucong Li , Jin Xiao , Bowei Zhang , Zhijian Zhou , Qianyu He , Fenglei Cao , Jiaqing Liang , Yuan Qi

The ability to reason beyond established knowledge allows Organic Chemists to solve synthetic problems and to invent novel transformations. Here, we propose a model which mimics chemical reasoning and formalises reaction prediction as…

人工智能 · 计算机科学 2017-12-27 Marwin H. S. Segler , Mark P. Waller

While showing impressive performance on various kinds of learning tasks, it is yet unclear whether deep learning models have the ability to robustly tackle reasoning tasks. than by learning the underlying reasoning process that is actually…

机器学习 · 计算机科学 2022-10-06 Andrea Valenti , Davide Bacciu , Antonio Vergari

Photons are a natural resource in quantum information, and the last decade showed significant progress in high-quality single photon generation and detection. Furthermore, photonic qubits are easy to manipulate and do not require…

Although large language models (LLMs) have significant potential to advance chemical discovery, current LLMs lack core chemical knowledge, produce unreliable reasoning trajectories, and exhibit suboptimal performance across diverse chemical…

We investigate the computational power of creating steady-states of quantum dissipative systems whose evolution is governed by time-independent and local couplings to a memoryless environment. We show that such a model allows for efficient…

量子物理 · 物理学 2009-09-24 Frank Verstraete , Michael M. Wolf , J. Ignacio Cirac

The conductor-like polarization model (C-PCM) with switching/Gaussian smooth discretization is a widely used implicit solvation model in chemical simulations. However, its application in quantum mechanical calculations of large-scale…

化学物理 · 物理学 2015-07-03 Fang Liu , Nathan Luehr , Heather J. Kulik , Todd J. Martínez

Computing the electronic structure of molecules with high precision is a central challenge in the field of quantum chemistry. Despite the enormous success of approximate methods, tackling this problem exactly with conventional computers is…

量子物理 · 物理学 2020-10-20 J. Argüello-Luengo , A. González-Tudela , T. Shi , P. Zoller , J. I. Cirac

This paper describes a type of infinitary computer (a hypercomputer) capable of computing truth in initial levels of the set theoretic universe, V. The proper class of such hypercomputers is called a universal hypercomputer. There are two…

逻辑 · 数学 2019-05-13 Andrew Powell