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Learning compact and interpretable representations of data is a critical challenge in scientific image analysis. Here, we introduce Affinity-VAE, a generative model that enables us to impose our scientific intuition about the similarity of…

Bayesian optimisation in the latent space of a Variational AutoEncoder (VAE) is a powerful framework for optimisation tasks over complex structured domains, such as the space of scientifically interesting molecules. However, existing…

机器学习 · 计算机科学 2025-07-08 Henry B. Moss , Sebastian W. Ober , Tom Diethe

Generative modeling and self-supervised learning have in recent years made great strides towards learning from data in a completely unsupervised way. There is still however an open area of investigation into guiding a neural network to…

机器学习 · 计算机科学 2023-05-17 Vaishnavi Patil , Matthew Evanusa , Joseph JaJa

Latent diffusion models have emerged as the dominant framework for high-fidelity and efficient image generation, owing to their ability to learn diffusion processes in compact latent spaces. However, while previous research has focused…

计算机视觉与模式识别 · 计算机科学 2026-03-24 Qifan Li , Xingyu Zhou , Jinhua Zhang , Weiyi You , Shuhang Gu

As deep Variational Auto-Encoder (VAE) frameworks become more widely used for modeling biomolecular simulation data, we emphasize the capability of the VAE architecture to concurrently maximize the timescale of the latent space while…

化学物理 · 物理学 2021-12-08 Hannah K. Wayment-Steele , Vijay S. Pande

VAEs (Variational AutoEncoders) have proved to be powerful in the context of density modeling and have been used in a variety of contexts for creative purposes. In many settings, the data we model possesses continuous attributes that we…

机器学习 · 计算机科学 2017-07-18 Gaëtan Hadjeres , Frank Nielsen , François Pachet

Reducing token count is crucial for efficient training and inference of latent diffusion models, especially at high resolution. A common strategy is to build high-compression image tokenizers with more channels per token. However, when…

计算机视觉与模式识别 · 计算机科学 2026-03-24 Xin Cai , Zhiyuan You , Zhoutong Zhang , Tianfan Xue

This paper advances the theory and practice of Domain Generalization (DG) in machine learning. We consider the typical DG setting where the hypothesis is composed of a representation mapping followed by a labeling function. Within this…

机器学习 · 计算机科学 2023-05-23 Boyang Lyu , Thuan Nguyen , Prakash Ishwar , Matthias Scheutz , Shuchin Aeron

Autoencoders empower state-of-the-art image and video generative models by compressing pixels into a latent space through visual tokenization. Although recent advances have alleviated the performance degradation of autoencoders under high…

计算机视觉与模式识别 · 计算机科学 2026-01-14 Dongxu Liu , Jiahui Zhu , Yuang Peng , Haomiao Tang , Yuwei Chen , Chunrui Han , Zheng Ge , Daxin Jiang , Mingxue Liao

We propose a method for learning topology-preserving data representations (dimensionality reduction). The method aims to provide topological similarity between the data manifold and its latent representation via enforcing the similarity in…

Variational Autoencoder (VAE) and its variations are classic generative models by learning a low-dimensional latent representation to satisfy some prior distribution (e.g., Gaussian distribution). Their advantages over GAN are that they can…

计算机视觉与模式识别 · 计算机科学 2020-09-24 Cong Geng , Jia Wang , Li Chen , Zhiyong Gao

Deep learning (DL) methods where interpretability is intrinsically considered as part of the model are required to better understand the relationship of clinical and imaging-based attributes with DL outcomes, thus facilitating their use in…

图像与视频处理 · 电气工程与系统科学 2022-12-13 Irem Cetin , Maialen Stephens , Oscar Camara , Miguel Angel Gonzalez Ballester

Single-cell perturbation prediction aims to infer how cells respond to unseen interventions and to achieve out-of-distribution (OOD) generalization, providing a computational route to understanding how perturbations reshape cellular…

机器学习 · 计算机科学 2026-05-26 Wenkang Jiang , Yuhang Liu , Erdun Gao , Ehsan Abbasnejad , Lina Yao , Javen Qinfeng Shi

The deployment of reinforcement learning (RL)-based controllers on physical systems is often limited by poor generalization to real-world scenarios, known as the simulation-to-reality (sim-to-real) gap. This gap is particularly challenging…

机器学习 · 计算机科学 2026-05-12 Alex E. Ballentine , Nachiket U. Bapat , Raghvendra V. Cowlagi

Continuous speech representations based on Variational Autoencoders (VAEs) have emerged as a promising alternative to traditional spectrogram or discrete token based features for speech generation and reconstruction. Recent research has…

声音 · 计算机科学 2026-05-26 Changhao Cheng , Wei Wang , Wangyou Zhang , Dongya Jia , Jian Wu , Zhuo Chen , Yanmin Qian

Latent Diffusion Models (LDMs) rely heavily on the compressed latent space provided by Variational Autoencoders (VAEs) for high-quality image generation. Recent studies have attempted to obtain generation-friendly VAEs by directly adopting…

计算机视觉与模式识别 · 计算机科学 2026-03-17 John Page , Xuesong Niu , Kai Wu , Kun Gai

Most visual generative models compress images into a latent space before applying diffusion or autoregressive modelling. Yet, existing approaches such as VAEs and foundation model aligned encoders implicitly constrain the latent space…

计算机视觉与模式识别 · 计算机科学 2025-12-09 Sen Ye , Jianning Pei , Mengde Xu , Shuyang Gu , Chunyu Wang , Liwei Wang , Han Hu

Understanding teleconnections of large-scale modes of climate variability is relevant for seasonal predictability and support a dynamical understanding of climatic changes. While numerical model experiments are the most common approach for…

Large, multi-dimensional spatio-temporal datasets are omnipresent in modern science and engineering. An effective framework for handling such data are Gaussian process deep generative models (GP-DGMs), which employ GP priors over the latent…

Representation disentanglement is an important goal of representation learning that benefits various downstream tasks. To achieve this goal, many unsupervised learning representation disentanglement approaches have been developed. However,…

机器学习 · 计算机科学 2022-09-23 Jiageng Zhu , Hanchen Xie , Wael Abd-Almageed