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The integration of artificial intelligence (AI) into pathology is advancing precision medicine by improving diagnosis, treatment planning, and patient outcomes. Digitised whole-slide images (WSIs) capture rich spatial and morphological…

Revealing novel insights from the relationship between molecular measurements and pathology remains a very impactful application of machine learning in biomedicine. Data in this domain typically contain only a few observations but thousands…

Multiple instance learning (MIL) has become a preferred method for gigapixel whole slide image (WSI) classification without requiring patch-level annotations. Current MIL research primarily relies on embedding-based approaches, which…

计算机视觉与模式识别 · 计算机科学 2025-03-10 Bryan Wong , Sungrae Hong , Mun Yong Yi

Virtual immunohistochemistry (IHC) staining from hematoxylin and eosin (H&E) images can accelerate diagnostics by providing preliminary molecular insight directly from routine sections, reducing the need for repeat sectioning when tissue is…

计算机视觉与模式识别 · 计算机科学 2026-03-16 Jillur Rahman Saurav , Thuong Le Hoai Pham , Pritam Mukherjee , Paul Yi , Brent A. Orr , Jacob M. Luber

Patching gigapixel whole slide images (WSIs) is an important task in computational pathology. Some methods have been proposed to select a subset of patches as WSI representation for downstream tasks. While most of the computational…

图像与视频处理 · 电气工程与系统科学 2023-10-06 Peyman Nejat , Areej Alsaafin , Ghazal Alabtah , Nneka Comfere , Aaron Mangold , Dennis Murphree , Patricija Zot , Saba Yasir , Joaquin J. Garcia , H. R. Tizhoosh

Developing self-supervised learning (SSL) models that can learn universal and transferable representations of H&E gigapixel whole-slide images (WSIs) is becoming increasingly valuable in computational pathology. These models hold the…

图像与视频处理 · 电气工程与系统科学 2024-08-07 Guillaume Jaume , Anurag Vaidya , Andrew Zhang , Andrew H. Song , Richard J. Chen , Sharifa Sahai , Dandan Mo , Emilio Madrigal , Long Phi Le , Faisal Mahmood

Although neural networks have proven very successful in a number of medical image analysis applications, their use remains difficult when targeting subtle tasks such as the identification of barely visible brain lesions, especially given…

图像与视频处理 · 电气工程与系统科学 2021-10-26 Verónica Muñoz-Ramírez , Nicolas Pinon , Florence Forbes , Carole Lartizen , Michel Dojat

Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

图像与视频处理 · 电气工程与系统科学 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

Generalization is one of the main challenges of computational pathology. Slide preparation heterogeneity and the diversity of scanners lead to poor model performance when used on data from medical centers not seen during training. In order…

图像与视频处理 · 电气工程与系统科学 2024-01-09 Nicolas Nerrienet , Rémy Peyret , Marie Sockeel , Stéphane Sockeel

Objective: This work addresses two key problems of skin lesion classification. The first problem is the effective use of high-resolution images with pretrained standard architectures for image classification. The second problem is the high…

计算机视觉与模式识别 · 计算机科学 2019-05-10 Nils Gessert , Thilo Sentker , Frederic Madesta , Rüdiger Schmitz , Helge Kniep , Ivo Baltruschat , René Werner , Alexander Schlaefer

The rapid growth of digital pathology in recent years has provided an ideal opportunity for the development of artificial intelligence-based tools to improve the accuracy and efficiency of clinical diagnoses. One of the significant…

图像与视频处理 · 电气工程与系统科学 2024-03-08 Jack Breen , Kieran Zucker , Katie Allen , Nishant Ravikumar , Nicolas M. Orsi

Digitized Histological diagnosis is in increasing demand. However, color variations due to various factors are imposing obstacles to the diagnosis process. The problem of stain color variations is a well-defined problem with many proposed…

计算机视觉与模式识别 · 计算机科学 2018-04-06 M Tarek Shaban , Christoph Baur , Nassir Navab , Shadi Albarqouni

Whole slide imaging (WSI) has recently been cleared for primary diagnosis in the US. A critical challenge of WSI is to perform accurate focusing in high speed. Traditional systems create a focus map prior to scanning. For each focus point…

计算机视觉与模式识别 · 计算机科学 2019-04-26 Jun Liao , Yutong Jiang , Zichao Bian , Bahareh Mahrou , Aparna Nambiar , Alexander W. Magsam , Kaikai Guo , Yong Ku Cho , Guoan Zheng

Whole Slide Images (WSIs) or histopathology images are used in digital pathology. WSIs pose great challenges to deep learning models for clinical diagnosis, owing to their size and lack of pixel-level annotations. With the recent…

We solve the image denoising problem with a dictionary learning technique by writing a convex functional of a new form. This functional contains beside the usual sparsity inducing term and fidelity term, a new term which induces similarity…

数值分析 · 数学 2015-06-02 Alessandro Mirone , Emmanuel Brun , Paola Coan

Latest diffusion models have shown promising results in category-level 6D object pose estimation by modeling the conditional pose distribution with depth image input. The existing methods, however, suffer from slow convergence during…

计算机视觉与模式识别 · 计算机科学 2025-10-07 Seunghyun Lee , Tae-Kyun Kim

Computational pathology needs whole-slide image (WSI) foundation models that transfer across diverse clinical tasks, yet current approaches remain largely slide-centric, often depend on private data and expensive paired-report supervision,…

计算机视觉与模式识别 · 计算机科学 2026-04-02 Yousef Kotp , Vincent Quoc-Huy Trinh , Christopher Pal , Mahdi S. Hosseini

In malware detection, dynamic analysis extracts the runtime behavior of malware samples in a controlled environment and static analysis extracts features using reverse engineering tools. While the former faces the challenges of…

密码学与安全 · 计算机科学 2022-11-28 Mao V. Ngo , Tram Truong-Huu , Dima Rabadi , Jia Yi Loo , Sin G. Teo

Image restoration, or inverse problems in image processing, has long been an extensively studied topic. In recent years supervised learning approaches have become a popular strategy attempting to tackle this task. Unfortunately, most…

图像与视频处理 · 电气工程与系统科学 2024-09-24 Deborah Pereg

Diffusion models are powerful, but they require a lot of time and data to train. We propose Patch Diffusion, a generic patch-wise training framework, to significantly reduce the training time costs while improving data efficiency, which…

计算机视觉与模式识别 · 计算机科学 2023-10-20 Zhendong Wang , Yifan Jiang , Huangjie Zheng , Peihao Wang , Pengcheng He , Zhangyang Wang , Weizhu Chen , Mingyuan Zhou