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Schizophrenia (SZ) is a serious mental disorder that could seriously affect the patient's quality of life. In recent years, detection of SZ based on deep learning (DL) using electroencephalogram (EEG) has received increasing attention. In…

神经元与认知 · 定量生物学 2022-07-12 Yihan Wu , Min Xia , Xiuzhu Wang , Yangsong Zhang

The current methods for diagnosing Alzheimer Disease using Magnetic Resonance Imaging (MRI) have significant limitations. Many previous studies used 2D Transformers to analyze individual brain slices independently, potentially losing…

计算机视觉与模式识别 · 计算机科学 2026-03-03 Juan A. Castro-Silva , Maria N. Moreno Garcia , Diego H. Peluffo-Ordoñez

Clinical studies reveal disruptions in brain structural connectivity (SC) and functional connectivity (FC) in neuropsychiatric disorders such as schizophrenia (SZ). Traditional approaches might rely solely on SC due to limited functional…

图像与视频处理 · 电气工程与系统科学 2026-01-27 Badhan Mazumder , Ayush Kanyal , Lei Wu , Vince D. Calhoun , Dong Hye Ye

Nowadays, many people worldwide suffer from brain disorders, and their health is in danger. So far, numerous methods have been proposed for the diagnosis of Schizophrenia (SZ) and attention deficit hyperactivity disorder (ADHD), among which…

Gaining insights into the structural and functional mechanisms of the brain has been a longstanding focus in neuroscience research, particularly in the context of understanding and treating neuropsychiatric disorders such as Schizophrenia…

计算机视觉与模式识别 · 计算机科学 2026-01-27 Badhan Mazumder , Lei Wu , Vince D. Calhoun , Dong Hye Ye

Modularity plays an important role in brain networks' architecture and influences its dynamics and the ability to integrate and segregate different modules of cerebral regions. Alterations in community structure are associated with several…

神经元与认知 · 定量生物学 2018-05-14 M. Cinelli , I. Echegoyen , M. Oliveira , S. Orellana , T. Gili

Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder characterized by progressive cognitive decline and widespread epigenetic dysregulation in the brain. DNA methylation, as a stable yet dynamic epigenetic modification,…

基因组学 · 定量生物学 2026-01-05 Gang Qu , Guanghao Li , Zhongming Zhao

Structural magnetic resonance imaging (sMRI) is widely used for brain neurological disease diagnosis; while longitudinal MRIs are often collected to monitor and capture disease progression, as clinically used in diagnosing Alzheimer's…

计算机视觉与模式识别 · 计算机科学 2023-12-18 Qiuhui Chen , Yi Hong

Advances in artificial intelligence (AI) and deep learning have improved diagnostic capabilities in healthcare, yet limited interpretability continues to hinder clinical adoption. Schizophrenia, a complex disorder with diverse symptoms…

音频与语音处理 · 电气工程与系统科学 2025-11-06 Gowtham Premananth , Carol Espy-Wilson

This paper presents a novel multimodal framework to distinguish between different symptom classes of subjects in the schizophrenia spectrum and healthy controls using audio, video, and text modalities. We implemented Convolution Neural…

音频与语音处理 · 电气工程与系统科学 2024-09-17 Gowtham Premananth , Yashish M. Siriwardena , Philip Resnik , Sonia Bansal , Deanna L. Kelly , Carol Espy-Wilson

The wide variety of brain imaging technologies allows us to exploit information inherent to different data modalities. The richness of multimodal datasets may increase predictive power and reveal latent variables that otherwise would have…

计算机视觉与模式识别 · 计算机科学 2018-04-13 Alvaro Ulloa , Sergey Plis , Vince Calhoun

Schizophrenia (SZ) is a brain disorder leading to detached mind's normally integrated processes. Hence, the exploration of the symptoms in relation to functional connectivity (FC) had great relevance in the field. FC can be investigated on…

神经元与认知 · 定量生物学 2026-04-08 Davide Coluzzi , Giuseppe Baselli

Schizophrenia is a severe mental health condition that requires a long and complicated diagnostic process. However, early diagnosis is vital to control symptoms. Deep learning has recently become a popular way to analyse and interpret…

机器学习 · 计算机科学 2022-04-01 Daniel Organisciak , Hubert P. H. Shum , Ephraim Nwoye , Wai Lok Woo

Schizophrenia is a globally prevalent psychiatric disorder that severely impairs daily life. Schizophrenia is caused by dopamine imbalances in the fronto-striatal pathways of the brain, which influences fine motor control in the cerebellum.…

计算机视觉与模式识别 · 计算机科学 2024-08-14 Rafael Castro , Ishaan Patel , Tarun Patanjali , Priya Iyer

This study focuses on how different modalities of human communication can be used to distinguish between healthy controls and subjects with schizophrenia who exhibit strong positive symptoms. We developed a multi-modal schizophrenia…

信号处理 · 电气工程与系统科学 2024-04-22 Gowtham Premananth , Yashish M. Siriwardena , Philip Resnik , Carol Espy-Wilson

We exploit altered patterns in brain functional connectivity as features for automatic discriminative analysis of neuropsychiatric patients. Deep learning methods have been introduced to functional network classification only very recently…

机器学习 · 计算机科学 2020-04-27 Chun-Ren Phang , Chee-Ming Ting , Fuad Noman , Hernando Ombao

Major depressive disorder (MDD) is a prevalent mental disorder associated with complex neurobiological changes that cannot be fully captured using a single imaging modality. The use of multimodal magnetic resonance imaging (MRI) provides a…

计算机视觉与模式识别 · 计算机科学 2026-04-14 Nojod M. Alotaibi , Areej M. Alhothali

Machine learning models have been successfully employed in the diagnosis of Schizophrenia disease. The impact of classification models and the feature selection techniques on the diagnosis of Schizophrenia have not been evaluated. Here, we…

机器学习 · 计算机科学 2022-07-05 M. Tanveer , Jatin Jangir , M. A. Ganaie , Iman Beheshti , M. Tabish , Nikunj Chhabra

Gene expression represents a fundamental interface between genes and environment in the development and ongoing plasticity of the human organism. Individual differences in gene expression are likely to underpin much of human diversity,…

基因组学 · 定量生物学 2019-05-31 Akram Yazdani , Raul Mendez Giraldez , Ahmad Samiei

Despite the impact of psychiatric disorders on clinical health, early-stage diagnosis remains a challenge. Machine learning studies have shown that classifiers tend to be overly narrow in the diagnosis prediction task. The overlap between…