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Cerebral perfusion plays a crucial role in maintaining brain function and is tightly coupled with neuronal activity. While previous studies have examined cerebral perfusion trajectories across development and aging, precise characterization…

神经元与认知 · 定量生物学 2025-02-13 Xinglin Zeng , Yiran Li , Lin Hua , Ruoxi Lu , Lucas Lemos Franco , Peter Kochunov , Shuo Chen , John A Detre , Ze Wang

Classification models that provide human-interpretable explanations enhance clinicians' trust and usability in medical image diagnosis. One research focus is the integration and prediction of pathology-related visual attributes used by…

计算机视觉与模式识别 · 计算机科学 2025-08-04 Luisa Gallée , Catharina Silvia Lisson , Christoph Gerhard Lisson , Daniela Drees , Felix Weig , Daniel Vogele , Meinrad Beer , Michael Götz

Quantitative characterization of disease progression using longitudinal data can provide long-term predictions for the pathological stages of individuals. This work studies the robust modeling of Alzheimer's disease progression using…

Brain imaging has allowed neuroscientists to analyze brain morphology in genetic and neurodevelopmental disorders, such as Down syndrome, pinpointing regions of interest to unravel the neuroanatomical underpinnings of cognitive impairment…

计算机视觉与模式识别 · 计算机科学 2024-09-23 Jordi Malé , Juan Fortea , Mateus Rozalem Aranha , Yann Heuzé , Neus Martínez-Abadías , Xavier Sevillano

In order to find effective treatments for Alzheimer's disease (AD), we need to identify subjects at risk of AD as early as possible. To this end, recently developed disease progression models can be used to perform early diagnosis, as well…

定量方法 · 定量生物学 2020-03-11 Razvan V. Marinescu

The application of supervised models to clinical screening tasks is challenging due to the need for annotated data for each considered pathology. Unsupervised Anomaly Detection (UAD) is an alternative approach that aims to identify any…

图像与视频处理 · 电气工程与系统科学 2025-01-24 Finn Behrendt , Debayan Bhattacharya , Robin Mieling , Lennart Maack , Julia Krüger , Roland Opfer , Alexander Schlaefer

We introduce a wide and deep neural network for prediction of progression from patients with mild cognitive impairment to Alzheimer's disease. Information from anatomical shape and tabular clinical data (demographics, biomarkers) are fused…

机器学习 · 计算机科学 2020-04-01 Sebastian Pölsterl , Ignacio Sarasua , Benjamín Gutiérrez-Becker , Christian Wachinger

Accurate diagnosis of psychiatric disorders plays a critical role in improving the quality of life for patients and potentially supports the development of new treatments. Many studies have been conducted on machine learning techniques that…

机器学习 · 统计学 2019-04-15 Takashi Matsubara , Tetsuo Tashiro , Kuniaki Uehara

Diffusion models surpass previous generative models in sample quality and training stability. Recent works have shown the advantages of diffusion models in improving reinforcement learning (RL) solutions. This survey aims to provide an…

机器学习 · 计算机科学 2024-02-26 Zhengbang Zhu , Hanye Zhao , Haoran He , Yichao Zhong , Shenyu Zhang , Haoquan Guo , Tingting Chen , Weinan Zhang

Diffusion Models (DMs), as a leading class of generative models, offer key advantages for reinforcement learning (RL), including multi-modal expressiveness, stable training, and trajectory-level planning. This survey delivers a…

机器学习 · 计算机科学 2025-10-15 Changfu Xu , Jianxiong Guo , Yuzhu Liang , Haiyang Huang , Haodong Zou , Xi Zheng , Shui Yu , Xiaowen Chu , Jiannong Cao , Tian Wang

Early detection of anomalies in medical images such as brain MRI is highly relevant for diagnosis and treatment of many conditions. Supervised machine learning methods are limited to a small number of pathologies where there is good…

计算机视觉与模式识别 · 计算机科学 2023-12-05 Alexander Frotscher , Jaivardhan Kapoor , Thomas Wolfers , Christian F. Baumgartner

Accurate modeling of cognitive decline in Alzheimer's disease is essential for early stratification and personalized management. While tabular predictors provide robust markers of global risk, their ability to capture subtle brain changes…

计算机视觉与模式识别 · 计算机科学 2025-11-19 Nathaniel Putera , Daniel Vilet Rodríguez , Noah Videcrantz , Julia Machnio , Mostafa Mehdipour Ghazi

The rapid global aging trend has led to an increase in dementia cases, including Alzheimer's disease, underscoring the urgent need for early and accurate diagnostic methods. Traditional diagnostic techniques, such as cognitive tests,…

机器学习 · 计算机科学 2024-09-06 Juan A. Berrios Moya

While Autoregressive (AR) Transformer-based Generative Language Models are frequently employed for lookahead tasks, recent research suggests a potential discrepancy in their ability to perform planning tasks that require multi-step…

机器学习 · 计算机科学 2026-02-24 Itamar Trainin , Shauli Ravfogel , Omri Abend , Amir Feder

We propose a versatile framework for survival analysis that combines advanced concepts from statistics with deep learning. The presented framework is based on piecewise exponential models and thereby supports various survival tasks, such as…

This study introduces a deep learning framework for the inferential exploration of latent representations in 3D brain MRI, leveraging a simple convolutional autoencoder with a hierarchical encoder and a compact latent space. Trained on…

应用统计 · 统计学 2026-05-25 J. M. Gorriz , F. Segovia , C. Jimenez , J. E. Arco , F. J. Martinez , J Ramirez , S. Abulikemu , J. Suckling

Denoising diffusion models produce high-fidelity image samples by capturing the image distribution in a progressive manner while initializing with a simple distribution and compounding the distribution complexity. Although these models have…

计算机视觉与模式识别 · 计算机科学 2025-07-04 Ayantika Das , Moitreya Chaudhuri , Koushik Bhat , Keerthi Ram , Mihail Bota , Mohanasankar Sivaprakasam

Generative AI, powered by large language models (LLMs), has revolutionized applications across text, audio, images, and video. This study focuses on developing and evaluating encoder-decoder architectures for the American Sign Language…

机器学习 · 计算机科学 2025-01-14 Vouk Praun-Petrovic , Aadhvika Koundinya , Lavanya Prahallad

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

图像与视频处理 · 电气工程与系统科学 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

We introduce Autoregressive Diffusion Models (ARDMs), a model class encompassing and generalizing order-agnostic autoregressive models (Uria et al., 2014) and absorbing discrete diffusion (Austin et al., 2021), which we show are special…

机器学习 · 计算机科学 2022-02-03 Emiel Hoogeboom , Alexey A. Gritsenko , Jasmijn Bastings , Ben Poole , Rianne van den Berg , Tim Salimans