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In pathological research, education, and clinical practice, the decision-making process based on pathological images is critically important. This significance extends to digital pathology image analysis: its adequacy is demonstrated by the…

图像与视频处理 · 电气工程与系统科学 2024-08-19 Zhi-Bo Liu , Xiaobo Pang , Jizhao Wang , Shuai Liu , Chen Li

Extracting rich phenotype information, such as cell density and arrangement, from whole slide histology images (WSIs), requires analysis of large field of view, i.e more contexual information. This can be achieved through analyzing the…

计算机视觉与模式识别 · 计算机科学 2022-03-30 Saarthak Kapse , Srijan Das , Prateek Prasanna

A Whole Slide Image (WSI) is a high-resolution digital image created by scanning an entire glass slide containing a biological specimen, such as tissue sections or cell samples, at multiple magnifications. These images are digitally…

The scarcity of publicly available medical imaging data limits the development of effective AI models. This work proposes a memory-efficient patch-wise denoising diffusion probabilistic model (DDPM) for generating synthetic medical images,…

图像与视频处理 · 电气工程与系统科学 2024-10-17 Kathrin Khadra , Utku Türkbey

Whole slide image (WSI) analysis in digital pathology presents unique challenges due to the gigapixel resolution of WSIs and the scarcity of dense supervision signals. While Multiple Instance Learning (MIL) is a natural fit for slide-level…

计算机视觉与模式识别 · 计算机科学 2025-08-21 Sofiène Boutaj , Marin Scalbert , Pierre Marza , Florent Couzinie-Devy , Maria Vakalopoulou , Stergios Christodoulidis

Advancements in AI for medical imaging offer significant potential. However, their applications are constrained by the limited availability of data and the reluctance of medical centers to share it due to patient privacy concerns.…

Visual microscopic study of diseased tissue by pathologists has been the cornerstone for cancer diagnosis and prognostication for more than a century. Recently, deep learning methods have made significant advances in the analysis and…

图像与视频处理 · 电气工程与系统科学 2022-09-30 Puria Azadi Moghadam , Sanne Van Dalen , Karina C. Martin , Jochen Lennerz , Stephen Yip , Hossein Farahani , Ali Bashashati

Tissue phenotyping is a fundamental computational pathology (CPath) task in learning objective characterizations of histopathologic biomarkers in anatomic pathology. However, whole-slide imaging (WSI) poses a complex computer vision problem…

Objective: We develop a computer-aided diagnosis (CAD) system using deep learning approaches for lesion detection and classification on whole-slide images (WSIs) with breast cancer. The deep features being distinguishing in classification…

图像与视频处理 · 电气工程与系统科学 2021-08-29 Wei-Wen Hsu , Yongfang Wu , Chang Hao , Yu-Ling Hou , Xiang Gao , Yun Shao , Xueli Zhang , Tao He , Yanhong Tai

Artificial Intelligence (AI) has great potential to improve health outcomes by training systems on vast digitized clinical datasets. Computational Pathology, with its massive amounts of microscopy image data and impact on diagnostics and…

图像与视频处理 · 电气工程与系统科学 2024-05-24 Gabriele Campanella , Eugene Fluder , Jennifer Zeng , Chad Vanderbilt , Thomas J. Fuchs

Histology imaging is an essential diagnosis method to finalize the grade and stage of cancer of different tissues, especially for breast cancer diagnosis. Specialists often disagree on the final diagnosis on biopsy tissue due to the complex…

计算机视觉与模式识别 · 计算机科学 2019-09-17 Yongxiang Huang , Albert Chi-shing Chung

Whole slide image (WSI) analysis has emerged as an increasingly essential technique in computational pathology. Recent advances in the pathology foundation models (FMs) have demonstrated significant advantages in deriving meaningful…

计算机视觉与模式识别 · 计算机科学 2025-11-21 Zhidong Yang , Xiuhui Shi , Wei Ba , Zhigang Song , Haijing Luan , Taiyuan Hu , Senlin Lin , Jiguang Wang , Shaohua Kevin Zhou , Rui Yan

Optical coherence tomography (OCT) image analysis plays an important role in the field of ophthalmology. Current successful analysis models rely on available large datasets, which can be challenging to be obtained for certain tasks. The use…

图像与视频处理 · 电气工程与系统科学 2024-05-28 Kun Huang , Xiao Ma , Yuhan Zhang , Na Su , Songtao Yuan , Yong Liu , Qiang Chen , Huazhu Fu

Diffusion models for image generation have been a subject of increasing interest due to their ability to generate diverse, high-quality images. Image generation has immense potential in medical imaging because open-source medical images are…

计算机视觉与模式识别 · 计算机科学 2025-02-13 Benoit Freiche , Anthony El-Khoury , Ali Nasiri-Sarvi , Mahdi S. Hosseini , Damien Garcia , Adrian Basarab , Mathieu Boily , Hassan Rivaz

The rapid identification and accurate diagnosis of breast cancer, known as the killer of women, have become greatly significant for those patients. Numerous breast cancer histopathological image classification methods have been proposed.…

图像与视频处理 · 电气工程与系统科学 2023-06-27 Luyuan Xie , Cong Li , Zirui Wang , Xin Zhang , Boyan Chen , Qingni Shen , Zhonghai Wu

This paper contributes to the "BraTS 2024 Brain MR Image Synthesis Challenge" and presents a conditional Wavelet Diffusion Model (cWDM) for directly solving a paired image-to-image translation task on high-resolution volumes. While deep…

图像与视频处理 · 电气工程与系统科学 2024-11-27 Paul Friedrich , Alicia Durrer , Julia Wolleb , Philippe C. Cattin

Representation learning for Whole Slide Images (WSIs) is pivotal in developing image-based systems to achieve higher precision in diagnostic pathology. We propose a two-stage framework for WSI representation learning. We sample relevant…

图像与视频处理 · 电气工程与系统科学 2020-04-20 Mohammed Adnan , Shivam Kalra , Hamid R. Tizhoosh

Hyperspectral image change detection (HSI-CD) has emerged as a crucial research area in remote sensing due to its ability to detect subtle changes on the earth's surface. Recently, diffusional denoising probabilistic models (DDPM) have…

计算机视觉与模式识别 · 计算机科学 2023-05-23 Xiangrong Zhang , Shunli Tian , Guanchun Wang , Huiyu Zhou , Licheng Jiao

Accurate prediction of placental diseases via whole slide images (WSIs) is critical for preventing severe maternal and fetal complications. However, WSI analysis presents significant computational challenges due to the massive data volume.…

计算机视觉与模式识别 · 计算机科学 2025-08-06 Hang Guo , Qing Zhang , Zixuan Gao , Siyuan Yang , Shulin Peng , Xiang Tao , Ting Yu , Yan Wang , Qingli Li

Uncertainty Quantification (UQ) is crucial for reliable image segmentation. Yet, while the field sees continual development of novel methods, a lack of agreed-upon benchmarks limits their systematic comparison and evaluation: Current UQ…