相关论文: Subgroup-Specific Risk-Controlled Dose Estimation …

The high precision and conformity of intensity-modulated particle therapy (IMPT) comes at the cost of susceptibility to treatment uncertainties in particle range and patient set-up. Dose uncertainty quantification and mitigation, which is…

Objectives: Pancreatic cancer is a lethal disease, hard to diagnose and usually results in poor prognosis and high mortality. Developing an artificial intelligence (AI) algorithm to accurately and universally predict the early cancer risk…

Machine learning (ML) has revolutionized medical prognostics by integrating advanced algorithms with clinical data to enhance disease prediction, risk assessment, and patient outcome forecasting. This comprehensive review critically…

Magnetic resonance spectroscopic imaging is a widely available imaging modality that can non-invasively provide a metabolic profile of the tissue of interest, yet is challenging to integrate clinically. One major reason is the expensive,…

Head and neck tumors and metastatic lymph nodes are crucial for treatment planning and prognostic analysis. Accurate segmentation and quantitative analysis of these structures require pixel-level annotation, making automated segmentation…

Rectal cancer is one of the most common diseases and a major cause of mortality. For deciding rectal cancer treatment plans, T-staging is important. However, evaluating the index from preoperative MRI images requires high radiologists'…

Radiotherapy is one of the primary treatment methods for tumors, but the organ movement caused by respiration limits its accuracy. Recently, 3D imaging from a single X-ray projection has received extensive attention as a promising approach…

Cyber-physical systems (CPSs) in modern real-time applications integrate numerous control units linked through communication networks, each responsible for executing a mix of real-time safety-critical and non-critical tasks. To ensure…

With the increasing number of financial services available online, the rate of financial fraud has also been increasing. The traffic and transaction rates on the internet have increased considerably, leading to a need for fast…

Background: Radiotherapy treatment planning involves solving large-scale optimization problems that are often approximated and solved sub-optimally due to time constraints. Central to these problems is the dose influence matrix which…

It is possible to find the optimized radiation dose per session for a radiotherapy (RT) treatment, using a population dynamics model. This has already been done in a previous work for a protocol with 30 sessions and a fixed dose per…

Prognostication for lung cancer, a leading cause of mortality, remains a complex task, as it needs to quantify the associations of risk factors and health events spanning a patient's entire life. One challenge is that an individual's…

Radiation therapy is the primary method used to treat cancer in the clinic. Its goal is to deliver a precise dose to the planning target volume (PTV) while protecting the surrounding organs at risk (OARs). However, the traditional workflow…

Lung cancer remains the leading cause of cancer mortality, with CT imaging central to screening, prognosis, and treatment. Manual segmentation is variable and time-intensive, while deep learning (DL) offers automation but faces barriers to…

With the uptake of targeted therapies, instead of the "one-fits-all" approach, modern randomized clinical trials (RCTs) often aim to develop treatments that target a subgroup of patients. Motivated by analyzing the Age-Related Eye Disease…

Fueled by advances in both robust optimization theory and reinforcement learning (RL), robust Markov Decision Processes (RMDPs) have garnered increasing attention due to their powerful capability for sequential decision-making under…

Automation of brain tumors in 3D magnetic resonance images (MRIs) is key to assess the diagnostic and treatment of the disease. In recent years, convolutional neural networks (CNNs) have shown improved results in the task. However, high…

Importance: Lung cancer is the leading cause of cancer mortality in the US, responsible for more deaths than breast, prostate, colon and pancreas cancer combined and it has been recently demonstrated that low-dose computed tomography (CT)…

Magnetic Resonance Spectroscopy (MRS) provides valuable information to help with the identification and understanding of brain tumors, yet MRS is not a widely available medical imaging modality. Aiming to counter this issue, this research…

Breast cancer remains a leading cause of cancer-related mortality worldwide. Early detection is critical, yet manual histopathology analysis is complex and subject to inter-observer variability. While deep neural network-based diagnostic…