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Automated medical image segmentation inherently involves a certain degree of uncertainty. One key factor contributing to this uncertainty is the ambiguity that can arise in determining the boundaries of a target region of interest,…

图像与视频处理 · 电气工程与系统科学 2023-08-28 Qingqiao Hu , Hao Wang , Jing Luo , Yunhao Luo , Zhiheng Zhangg , Jan S. Kirschke , Benedikt Wiestler , Bjoern Menze , Jianguo Zhang , Hongwei Bran Li

Whether a correlation exists between the radio and gamma-ray flux densities of blazars is a long-standing question, and one that is difficult to answer confidently because of various observational biases which may either dilute or…

There exist many methods for sensitivity analysis readily available to the practitioner. While each seeks to help the modeler answer the same general question -- How do sources of uncertainty or changes in the model inputs relate to…

统计方法学 · 统计学 2025-06-16 Devin Francom , Abigael Nachtsheim

The precision of contouring target structures and organs-at-risk (OAR) in radiotherapy planning is crucial for ensuring treatment efficacy and patient safety. Recent advancements in deep learning (DL) have significantly improved OAR…

图像与视频处理 · 电气工程与系统科学 2024-09-30 Marvin Tom Teichmann , Manasi Datar , Lisa Kratzke , Fernando Vega , Florin C. Ghesu

Introducing accelerated reconstruction algorithms into clinical settings requires measures of uncertainty quantification that accurately assess the relevant uncertainty introduced by the reconstruction algorithm. Many currently deployed…

图像与视频处理 · 电气工程与系统科学 2025-08-12 Luca L. C. Trautmann , Peter A. Wijeratne , Itamar Ronen , Ivor J. A. Simpson

In this work, we have investigated the sensitivity of the effectiveness (TCP) of molecular radiotherapy (MRT) treatment to uncertainties of the dose rate curves that may appear when reconstructing those curves. We generated different dose…

医学物理 · 物理学 2025-02-03 Pedro Otero-Casal , Aldán Baliño , Sara Neira , Faustino Gómez , Juan Pardo-Montero

In a statistical analysis in Particle Physics, nuisance parameters can be introduced to take into account various types of systematic uncertainties. The best estimate of such a parameter is often modeled as a Gaussian distributed variable…

数据分析、统计与概率 · 物理学 2019-02-25 Glen Cowan

Sensitivity analysis (SA) has much to offer for a very large class of applications, such as model selection, calibration, optimization, quality assurance and many others. Sensitivity analysis offers crucial contextual information regarding…

While considerable advance has been made to account for statistical uncertainties in astronomical analyses, systematic instrumental uncertainties have been generally ignored. This can be crucial to a proper interpretation of analysis…

Sensitivity analysis informs causal inference by assessing the sensitivity of conclusions to departures from assumptions. The consistency assumption states that there are no hidden versions of treatment and that the outcome arising…

统计方法学 · 统计学 2025-12-29 Brian Knaeble , Qinyun Lin , Erich Kummerfeld , Kenneth A. Frank

Effective education in radiotherapy plan quality review requires a robust, regularly updated set of examples and the flexibility to demonstrate multiple possible planning approaches and their consequences. However, the current clinic-based…

Much of uncertainty quantification to date has focused on determining the effect of variables modeled probabilistically, and with a known distribution, on some physical or engineering system. We develop methods to obtain information on the…

数值分析 · 数学 2015-03-19 Kamaljit Chowdhary , Paul Dupuis

The radiological characterization of contaminated elements (walls, grounds, objects) from nuclear facilities often suffers from a too small number of measurements. In order to determine risk prediction bounds on the level of contamination,…

应用统计 · 统计学 2017-05-30 Géraud Blatman , Thibault Delage , Bertrand Iooss , Nadia Pérot

This work presents a detailed covariance and correlation matrix analysis for experimentally measured cross sections obtained using the activation technique. Both statistical and systematic contributions to the covariance matrix were…

核理论 · 物理学 2026-04-01 Tanmoy Bar

Uncertainty quantification is a primary challenge for reliable modeling and simulation of complex stochastic dynamics. Such problems are typically plagued with incomplete information that may enter as uncertainty in the model parameters, or…

概率论 · 数学 2015-07-15 Paul Dupuis , Markos A. Katsoulakis , Yannis Pantazis , Petr Plechac

Matching is a commonly used causal inference study design in observational studies. Through matching on measured confounders between different treatment groups, valid randomization inferences can be conducted under the no unmeasured…

统计方法学 · 统计学 2024-09-20 Jeffrey Zhang , Siyu Heng

Comparing outcomes across treatments is essential in medicine and public policy. To do so, researchers typically estimate a set of parameters, possibly counterfactual, with each targeting a different treatment. Treatment-specific means are…

统计方法学 · 统计学 2025-10-07 Alec McClean , Yiting Li , Sunjae Bae , Mara A. McAdams-DeMarco , Iván Díaz , Wenbo Wu

Nuclear security operations and forensic investigations require the utilization of a suite of instruments ranging from passive gamma spectrometers to high-precision laboratory sample analyzers. Gamma spectroscopy survey is further broken…

仪器与探测器 · 物理学 2026-02-03 L. E. Sinclair , P. R. B. Saull , A. McCann , A. M. L. MacLeod , N. J. Murtha , A. El-Jaby , G. Jonkmans

While spatial dose conformity delivered to a target volume has been pushed to its practical limits with advanced treatment planning and delivery, investigations in novel temporal dose delivery are unfolding new mechanisms. Recent advances…

Generative Artificial Intelligence (AI) can be used to automatically generate medical reports based on transcripts of medical consultations. The aim is to reduce the administrative burden that healthcare professionals face. The accuracy of…

计算与语言 · 计算机科学 2024-01-09 Wouter Faber , Renske Eline Bootsma , Tom Huibers , Sandra van Dulmen , Sjaak Brinkkemper