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In recent years, medical information technology has made it possible for electronic health record (EHR) to store fairly complete clinical data. This has brought health care into the era of "big data". However, medical data are often sparse…

机器学习 · 计算机科学 2023-06-06 Weizhi Nie , Yuhe Yu , Chen Zhang , Dan Song , Lina Zhao , Yunpeng Bai

With a mortality rate of 5.4 million lives worldwide every year and a healthcare cost of more than 16 billion dollars in the USA alone, sepsis is one of the leading causes of hospital mortality and an increasing concern in the ageing…

机器学习 · 计算机科学 2021-05-12 Margherita Rosnati , Vincent Fortuin

Continuous diagnosis and prognosis are essential for intensive care patients. It can provide more opportunities for timely treatment and rational resource allocation, especially for sepsis, a main cause of death in ICU, and COVID-19, a new…

机器学习 · 计算机科学 2022-10-07 Chenxi Sun , Hongyan Li , Moxian Song , Derun Cai , Baofeng Zhang , Shenda Hong

Sepsis is an important cause of mortality, especially in intensive care unit (ICU) patients. Developing novel methods to identify early mortality is critical for improving survival outcomes in sepsis patients. Using the MIMIC-III database,…

计算机与社会 · 计算机科学 2021-12-03 Jiyoung Shin , Yikuan Li , Yuan Luo

Objective: Sepsis is a life-threatening condition caused by severe infection leading to acute organ dysfunction. This study proposes a data-driven metric and a continuous reward function to optimize personalized heparin therapy in surgical…

机器学习 · 计算机科学 2025-12-15 Jiang Liu , Yujie Li , Chan Zhou , Yihao Xie , Qilong Sun , Xin Shu , Peiwei Li , Chunyong Yang , Yiziting Zhu , Jiaqi Zhu , Yuwen Chen , Bo An , Hao Wu , Bin Yi

The disease trajectory for clinical sepsis, in terms of temporal cytokine and phenotypic dynamics, can be interpreted as a random dynamical system. The ability to make accurate predictions about patient state from clinical measurements has…

定量方法 · 定量生物学 2020-07-30 Dale Larie , Gary An , Chase Cockrell

Motivation: Survival analysis is a branch of statistics that is crucial in medicine for modeling the time to critical events such as death or relapse, in order to improve treatment strategies and patient outcomes. Selecting survival models…

Sepsis is a life-threatening disease with high morbidity, mortality and healthcare costs. The early prediction and administration of antibiotics and intravenous fluids is considered crucial for the treatment of sepsis and can save…

计算与语言 · 计算机科学 2021-07-26 Fred Qin , Vivek Madan , Ujjwal Ratan , Zohar Karnin , Vishaal Kapoor , Parminder Bhatia , Taha Kass-Hout

Sepsis is a life-threatening host response to infection associated with high mortality, morbidity, and health costs. Its management is highly time-sensitive since each hour of delayed treatment increases mortality due to irreversible organ…

机器学习 · 计算机科学 2020-10-16 Michael Moor , Max Horn , Bastian Rieck , Damian Roqueiro , Karsten Borgwardt

Accurate and interpretable mortality risk prediction in intensive care units (ICUs) remains a critical challenge due to the irregular temporal structure of electronic health records (EHRs), the complexity of longitudinal disease…

机器学习 · 计算机科学 2026-03-10 Zahra Jafari , Azadeh Zamanifar , Amirfarhad Farhadi

We study multiple rule-based and machine learning (ML) models for sepsis detection. We report the first neural network detection and prediction results on three categories of sepsis. We have used the retrospective Medical Information Mart…

机器学习 · 计算机科学 2019-03-07 Avijit Mitra , Khalid Ashraf

Despite decades of clinical research, sepsis remains a global public health crisis with high mortality, and morbidity. Currently, when sepsis is detected and the underlying pathogen is identified, organ damage may have already progressed to…

We design and implement a temporal convolutional network model to predict sepsis onset. Our model is trained on data extracted from MIMIC III database, based on a retrospective analysis of patients admitted to intensive care unit who did…

机器学习 · 计算机科学 2022-06-01 Xing Wang , Yuntian He

Sepsis is a life-threatening syndrome with high morbidity and mortality in hospitals. Early prediction of sepsis plays a crucial role in facilitating early interventions for septic patients. However, early sepsis prediction systems with…

机器学习 · 计算机科学 2025-03-20 Anni Zhou , Beyah Raheem , Rishikesan Kamaleswaran , Yao Xie

Although timely sepsis diagnosis and prompt interventions in Intensive Care Unit (ICU) patients are associated with reduced mortality, early clinical recognition is frequently impeded by non-specific signs of infection and failure to detect…

机器学习 · 计算机科学 2018-06-28 Tony Wang , Tom Velez , Emilia Apostolova , Tim Tschampel , Thuy L. Ngo , Joy Hardison

Sepsis is a life threatening condition that requires timely detection in intensive care settings. Traditional machine learning approaches, including Naive Bayes, Support Vector Machine (SVM), Random Forest, and XGBoost, often rely on manual…

机器学习 · 计算机科学 2025-09-03 Hejiang Cai , Di Wu , Ji Xu , Xiang Liu , Yiziting Zhu , Xin Shu , Yujie Li , Bin Yi

Sepsis is a condition caused by the body's overwhelming and life-threatening response to infection, which can lead to tissue damage, organ failure, and finally death. Common signs and symptoms include fever, increased heart rate, increased…

机器学习 · 计算机科学 2017-09-07 Eitam Sheetrit , Nir Nissim , Denis Klimov , Lior Fuchs , Yuval Elovici , Yuval Shahar

Predicting information cascade popularity is a fundamental problem in social networks. Capturing temporal attributes and cascade role information (e.g., cascade graphs and cascade sequences) is necessary for understanding the information…

社会与信息网络 · 计算机科学 2023-08-22 Xigang Sun , Jingya Zhou , Ling Liu , Wenqi Wei

Epileptic seizure forecasting, combined with the delivery of preventative therapies, holds the potential to greatly improve the quality of life for epilepsy patients and their caregivers. Forecasting seizures could prevent some potentially…

信号处理 · 电气工程与系统科学 2020-05-18 Nhan Duy Truong , Yikai Yang , Christina Maher , Armin Nikpour , Omid Kavehei

Information-theoretic quantities play a crucial role in understanding non-linear relationships between random variables and are widely used across scientific disciplines. However, estimating these quantities remains an open problem,…

机器学习 · 计算机科学 2025-02-28 Alberto Foresti , Giulio Franzese , Pietro Michiardi
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