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In this paper we study the problems of estimating heterogeneity in causal effects in experimental or observational studies and conducting inference about the magnitude of the differences in treatment effects across subsets of the…

机器学习 · 统计学 2022-06-08 Susan Athey , Guido Imbens

In a clustered observational study, treatment is assigned to groups and all units within the group are exposed to the treatment. Here, we use a clustered observational study (COS) design to estimate the effectiveness of Magnet Nursing…

统计方法学 · 统计学 2025-05-01 Melody Huang , Eli Ben-Michael , Matthew McHugh , Luke Keele

Sensitivity to unmeasured confounding is not typically a primary consideration in designing treated-control comparisons in observational studies. We introduce a framework allowing researchers to optimize robustness to omitted variable bias…

统计方法学 · 统计学 2024-07-19 Melody Huang , Dan Soriano , Samuel D. Pimentel

Mediation analysis in causal inference has traditionally focused on binary exposures and deterministic interventions, and a decomposition of the average treatment effect in terms of direct and indirect effects. In this paper we present an…

统计方法学 · 统计学 2020-11-17 Iván Díaz , Nima Hejazi

Debiased collaborative filtering aims to learn an unbiased prediction model by removing different biases in observational datasets. To solve this problem, one of the simple and effective methods is based on the propensity score, which…

信息检索 · 计算机科学 2024-05-01 Haoxuan Li , Chunyuan Zheng , Yanghao Xiao , Peng Wu , Zhi Geng , Xu Chen , Peng Cui

There is increasing interest in comparing institutions delivering healthcare in terms of disease-specific quality indicators (QIs) that capture processes or outcomes showing variations in the care provided. Such comparisons can be framed in…

统计方法学 · 统计学 2020-09-07 Bo Chen , Keith A. Lawson , Antonio Finelli , Olli Saarela

Observational studies require adjustment for confounding factors that are correlated with both the treatment and outcome. In the setting where the observed variables are tabular quantities such as average income in a neighborhood, tools…

机器学习 · 统计学 2023-01-31 Connor T. Jerzak , Fredrik Johansson , Adel Daoud

Unobserved effect modifiers can induce bias when generalizing causal effect estimates to target populations. In this work, we extend a sensitivity analysis framework assessing the robustness of study results to unobserved effect…

To estimate casual treatment effects, we propose a new matching approach based on the reduced covariates obtained from sufficient dimension reduction. Compared to the original covariates and the propensity score, which are commonly used for…

统计方法学 · 统计学 2017-02-03 Wei Luo , Yeying Zhu

Limited overlap between treated and control groups is a key challenge in observational analysis. Standard approaches like trimming importance weights can reduce variance but introduce a fundamental bias. We propose a sensitivity framework…

机器学习 · 统计学 2026-04-21 Yuanzhe Ma , Yian Huang , Hongseok Namkoong

Mediation analysis is a form of causal inference that investigates indirect effects and causal mechanisms. Confidence intervals for indirect effects play a central role in conducting inference. The problem is non-standard leading to…

计量经济学 · 经济学 2024-12-17 Kees Jan van Garderen , Noud van Giersbergen

Two problems that arise in making causal inferences for non-mortality outcomes such as bronchopulmonary dysplasia (BPD) are unmeasured confounding and censoring by death, i.e., the outcome is only observed when subjects survive. In…

统计方法学 · 统计学 2018-02-20 Kwonsang Lee , Scott A. Lorch , Dylan S. Small

Causal inference in observational studies typically requires making comparisons between groups that are dissimilar. For instance, researchers investigating the role of a prolonged duration of breastfeeding on child outcomes may be forced to…

应用统计 · 统计学 2013-12-02 Jennifer Hill , Yu-Sung Su

Causal mediation analysis provides techniques for defining and estimating effects that may be endowed with mechanistic interpretations. With many scientific investigations seeking to address mechanistic questions, causal direct and indirect…

Predicting the effect of interventions with many possible variations, e.g., therapeutic content that affects mental health outcomes or an earnings call transcript that drives movement in share price, is useful across several domains.…

机器学习 · 计算机科学 2026-05-27 Nikita Dhawan , Arnav Paruthi , Andrew Kim , Lovedeep Gondara , Jekaterina Novikova , Chris J. Maddison

To estimate direct and indirect effects of an exposure on an outcome from observed data strong assumptions about unconfoundedness are required. Since these assumptions cannot be tested using the observed data, a mediation analysis should…

统计理论 · 数学 2018-03-29 Anita Lindmark , Xavier de Luna , Marie Eriksson

Causal mediation analysis is routinely conducted by applied researchers in a variety of disciplines. The goal of such an analysis is to investigate alternative causal mechanisms by examining the roles of intermediate variables that lie in…

统计方法学 · 统计学 2010-11-05 Kosuke Imai , Luke Keele , Teppei Yamamoto

Analysis of observational studies increasingly confronts the challenge of determining which of a possibly high-dimensional set of available covariates are required to satisfy the assumption of ignorable treatment assignment for estimation…

统计方法学 · 统计学 2022-03-23 Chanmin Kim , Mauricio Tec , Corwin M Zigler

Due to unmeasured confounding, it is often not possible to identify causal effects from a postulated model. Nevertheless, we can ask for partial identification, which usually boils down to finding upper and lower bounds of a causal quantity…

机器学习 · 统计学 2022-03-01 Jakob Zeitler , Ricardo Silva

The estimation of heterogeneous treatment effects in the potential outcome setting is biased when there exists model misspecification or unobserved confounding. As these biases are unobservable, what model to use when remains a critical…

统计方法学 · 统计学 2024-05-09 Shonosuke Sugasawa , Kosaku Takanashi , Kenichiro McAlinn , Edoardo M. Airoldi