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Academic literature reviews have traditionally relied on techniques such as keyword searches and accumulation of relevant back-references, using databases like Google Scholar or IEEEXplore. However, both the precision and accuracy of these…

人机交互 · 计算机科学 2024-08-27 Hongye An , Arpit Narechania , Emily Wall , Kai Xu

Multimodal large language models (MLLMs) have emerged as powerful tools for computational pathology, offering unprecedented opportunities to integrate pathological images with language context for comprehensive diagnostic analysis. These…

The surging amount of biomedical literature & digital clinical records presents a growing need for text mining techniques that can not only identify but also semantically relate entities in unstructured data. In this paper we propose a text…

计算与语言 · 计算机科学 2021-12-28 Hasham Ul Haq , Veysel Kocaman , David Talby

Pneumonia has been one of the fatal diseases and has the potential to result in severe consequences within a short period of time, due to the flow of fluid in lungs, which leads to drowning. If not acted upon by drugs at the right time,…

计算机视觉与模式识别 · 计算机科学 2019-04-02 Can Jozef Saul , Deniz Yagmur Urey , Can Doruk Taktakoglu

Diabetic retinopathy (DR) grading from fundus images has attracted increasing interest in both academic and industrial communities. Most convolutional neural network (CNN) based algorithms treat DR grading as a classification task via…

计算机视觉与模式识别 · 计算机科学 2021-03-19 Yehui Yang , Fangxin Shang , Binghong Wu , Dalu Yang , Lei Wang , Yanwu Xu , Wensheng Zhang , Tianzhu Zhang

Reliable automatic diagnosis of Diabetic Retinopathy (DR) and Macular Edema (ME) is an invaluable asset in improving the rate of monitored patients among at-risk populations and in enabling earlier treatments before the pathology progresses…

图像与视频处理 · 电气工程与系统科学 2024-08-26 Gabriel Lepetit-Aimon , Clément Playout , Marie Carole Boucher , Renaud Duval , Michael H Brent , Farida Cheriet

Cancer surgery is a key treatment for gastrointestinal (GI) cancers, a group of cancers that account for more than 35% of cancer-related deaths worldwide, but postoperative complications are unpredictable and can be life-threatening. In…

Retinal blood vessel segmentation can extract clinically relevant information from fundus images. As manual tracing is cumbersome, algorithms based on Convolution Neural Networks have been developed. Such studies have used small publicly…

图像与视频处理 · 电气工程与系统科学 2024-06-24 Jeremiah Fadugba , Patrick Köhler , Lisa Koch , Petru Manescu , Philipp Berens

The paper reviews the state-of-the-art of foundation models, LLMs, generative AI, information retrieval and CBIR in digital pathology

信息检索 · 计算机科学 2024-03-20 H. R. Tizhoosh

Diabetic Retinopathy (DR) affects individuals with long-term diabetes. Without early diagnosis, DR can lead to vision loss. Fundus photography captures the structure of the retina along with abnormalities indicative of the stage of the…

计算机视觉与模式识别 · 计算机科学 2025-12-11 Anca Mihai , Adrian Groza

Objective: Electronic health records (EHR) data are prone to missingness and errors. Previously, we devised an "enriched" chart review protocol where a "roadmap" of auxiliary diagnoses (anchors) was used to recover missing values in EHR…

Deep learning models have shown immense promise in computational pathology (CPath) tasks, but their performance often suffers when applied to unseen data due to domain shifts. Addressing this requires domain generalization (DG) algorithms.…

计算机视觉与模式识别 · 计算机科学 2025-11-12 Neda Zamanitajeddin , Mostafa Jahanifar , Kesi Xu , Fouzia Siraj , Nasir Rajpoot

The scarcity of high-quality, labelled retinal imaging data, which presents a significant challenge in the development of machine learning models for ophthalmology, hinders progress in the field. Existing methods for synthesising Colour…

图像与视频处理 · 电气工程与系统科学 2025-07-18 Junzhi Ning , Cheng Tang , Kaijing Zhou , Diping Song , Lihao Liu , Ming Hu , Wei Li , Huihui Xu , Yanzhou Su , Tianbin Li , Jiyao Liu , Jin Ye , Sheng Zhang , Yuanfeng Ji , Junjun He

Large language models (LLMs) primarily trained on English texts, often face biases and inaccuracies in Chinese contexts. Their limitations are pronounced in fields like Traditional Chinese Medicine (TCM), where cultural and clinical…

计算与语言 · 计算机科学 2025-03-28 Yishen Liu , Shengda Luo , Zishao Zhong , Tongtong Wu , Jianguo Zhang , Peiyao Ou , Yong Liang , Liang Liu , Hudan Pan

With the remarkable success of representation learning for prediction problems, we have witnessed a rapid expansion of the use of machine learning and deep learning for the analysis of digital pathology and biopsy image patches. However,…

机器学习 · 计算机科学 2024-03-06 David Ahmedt-Aristizabal , Mohammad Ali Armin , Simon Denman , Clinton Fookes , Lars Petersson

Objective: Applying large language models (LLMs) to the clinical domain is challenging due to the context-heavy nature of processing medical records. Retrieval-augmented generation (RAG) offers a solution by facilitating reasoning over…

Protein-protein interactions (PPIs) are associated with various diseases, including cancer, infections, and neurodegenerative disorders. Obtaining three-dimensional structural information on these PPIs serves as a foundation to interfere…

生物大分子 · 定量生物学 2024-07-24 Xiaotong Xu , Alexandre M. J. J. Bonvin

Diabetic retinopathy (DR) is a diabetes complication that affects eyes. DR is a primary cause of blindness in working-age people and it is estimated that 3 to 4 million people with diabetes are blinded by DR every year worldwide. Early…

计算机视觉与模式识别 · 计算机科学 2019-11-21 Qilei Chen , Xinzi Sun , Ning Zhang , Yu Cao , Benyuan Liu

The segmentation of kidney layer structures, including cortex, outer stripe, inner stripe, and inner medulla within human kidney whole slide images (WSI) plays an essential role in automated image analysis in renal pathology. However, the…

图像与视频处理 · 电气工程与系统科学 2023-09-07 Muhao Liu , Chenyang Qi , Shunxing Bao , Quan Liu , Ruining Deng , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

Digital hematopathology requires cell-level analysis across diverse disease categories, including malignant disorders (e.g., leukemia), infectious conditions (e.g., malaria), and non-malignant red blood cell disorders (e.g., sickle cell…

计算机视觉与模式识别 · 计算机科学 2025-11-20 Abdul Rehman , Iqra Rasool , Ayisha Imran , Mohsen Ali , Waqas Sultani