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Single-cell data analysis has the potential to revolutionize personalized medicine by characterizing disease-associated molecular changes at the single-cell level. Advanced single-cell multimodal assays can now simultaneously measure…

定量方法 · 定量生物学 2026-01-05 Ali Anaissi , Seid Miad Zandavi , Weidong Huang , Junaid Akram , Basem Suleiman , Ali Braytee , Jie Hua

Instance segmentation enables the analysis of spatial and temporal properties of cells in microscopy images by identifying the pixels belonging to each cell. However, progress is constrained by the scarcity of high-quality labeled…

计算机视觉与模式识别 · 计算机科学 2026-04-14 Kaden Stillwagon , Alexandra Dunnum VandeLoo , Benjamin Magondu , Craig R. Forest

Learning disentangled representations is a fundamental task in multi-modal learning. In modern applications such as single-cell multi-omics, both shared and modality-specific features are critical for characterizing cell states and…

机器学习 · 统计学 2025-12-05 Yu Gui , Cong Ma , Zongming Ma

In the application of machine learning to remote sensing, labeled data is often scarce or expensive, which impedes the training of powerful models like deep convolutional neural networks. Although unlabeled data is abundant, recent…

计算机视觉与模式识别 · 计算机科学 2021-08-12 Aidan M. Swope , Xander H. Rudelis , Kyle T. Story

In this paper we propose a unified framework to simultaneously discover the number of clusters and group the data points into them using subspace clustering. Real data distributed in a high-dimensional space can be disentangled into a union…

计算机视觉与模式识别 · 计算机科学 2019-07-24 Jie Liang , Jufeng Yang , Ming-Ming Cheng , Paul L. Rosin , Liang Wang

In systems biomedicine, an experimenter encounters different potential sources of variation in data such as individual samples, multiple experimental conditions, and multi-variable network-level responses. In multiparametric cytometry,…

Patients with the COVID-19 infection may have pneumonia-like symptoms as well as respiratory problems which may harm the lungs. From medical images, coronavirus illness may be accurately identified and predicted using a variety of machine…

计算机视觉与模式识别 · 计算机科学 2023-02-20 Tareque Rahman Ornob , Gourab Roy , Enamul Hassan

Often, applications of self-supervised learning to 3D medical data opt to use 3D variants of successful 2D network architectures. Although promising approaches, they are significantly more computationally demanding to train, and thus reduce…

计算机视觉与模式识别 · 计算机科学 2024-02-27 David Torpey , Richard Klein

We propose a novel method for unsupervised semantic image segmentation based on mutual information maximization between local and global high-level image features. The core idea of our work is to leverage recent progress in self-supervised…

计算机视觉与模式识别 · 计算机科学 2021-10-08 Robert Harb , Patrick Knöbelreiter

Swift and accurate blood smear analysis is an effective diagnostic method for leukemia and other hematological malignancies. However, manual leukocyte count and morphological evaluation using a microscope is time-consuming and prone to…

计算机视觉与模式识别 · 计算机科学 2024-10-22 Chandravardhan Singh Raghaw , Arnav Sharma , Shubhi Bansal , Mohammad Zia Ur Rehman , Nagendra Kumar

Temporal data, obtained in the setting where it is only possible to observe one time point per experiment, is widely used in different research fields, yet remains insufficiently addressed from the statistical point of view. Such data often…

统计方法学 · 统计学 2025-03-10 Polina Arsenteva , Mohamed Amine Benadjaoud , Hervé Cardot

Computed Tomography (CT) scans provide a detailed image of the lungs, allowing clinicians to observe the extent of damage caused by COVID-19. The CT severity score (CTSS) based scoring method is used to identify the extent of lung…

图像与视频处理 · 电气工程与系统科学 2023-03-20 Anand Thyagachandran , Hema A Murthy

Recent technological advances have made it possible to collect high-dimensional genomic data along with clinical data on a large number of subjects. In the studies of chronic diseases such as cancer, it is of great interest to integrate…

统计方法学 · 统计学 2020-11-03 Hoi Min Ng , Binyan Jiang , Kin Yau Wong

Implicit Neural Representations (INRs) are widely used to encode data as continuous functions, enabling the visualization of large-scale multivariate scientific simulation data with reduced memory usage. However, existing INR-based methods…

计算机视觉与模式识别 · 计算机科学 2026-03-04 Hyunsoo Son , Jeonghyun Noh , Suemin Jeon , Chaoli Wang , Won-Ki Jeong

Covariate adjustment aims to improve the statistical efficiency of randomized trials by incorporating information from baseline covariates. Popular methods for covariate adjustment include analysis of covariance for continuous endpoints and…

统计方法学 · 统计学 2025-05-09 Zhiwei Zhang , Ya Wang , Dong Xi

In this study, we introduce a multi-modal approach that efficiently integrates multi-scale clinical and dermoscopy features within a single network, thereby substantially reducing model parameters. The proposed method includes three novel…

图像与视频处理 · 电气工程与系统科学 2024-03-31 Peng Tang , Tobias Lasser

Electronic Health Records have become popular sources of data for secondary research, but their use is hampered by the amount of effort it takes to overcome the sparsity, irregularity, and noise that they contain. Modern learning…

应用统计 · 统计学 2025-02-28 Jacek M. Bajor , Diego A. Mesa , Travis J. Osterman , Thomas A. Lasko

Counterfactual estimation over time is important in various applications, such as personalized medicine. However, time-dependent confounding bias in observational data still poses a significant challenge in achieving accurate and efficient…

机器学习 · 计算机科学 2026-03-13 Nghia D. Nguyen , Pablo Robles-Granda , Lav R. Varshney

While self-supervised learning techniques are often used to mining implicit knowledge from unlabeled data via modeling multiple views, it is unclear how to perform effective representation learning in a complex and inconsistent context. To…

计算机视觉与模式识别 · 计算机科学 2023-08-10 Jiangmeng Li , Wenwen Qiang , Changwen Zheng , Bing Su , Farid Razzak , Ji-Rong Wen , Hui Xiong