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Motivation: Drug discovery demands rapid quantification of compound-protein interaction (CPI). However, there is a lack of methods that can predict compound-protein affinity from sequences alone with high applicability, accuracy, and…

生物大分子 · 定量生物学 2020-12-17 Mostafa Karimi , Di Wu , Zhangyang Wang , Yang Shen

Researchers in the highly active field of intrusion detection largely rely on public datasets for their experimental evaluations. However, the large number of existing datasets, the discovery of previously unknown flaws therein, and the…

密码学与安全 · 计算机科学 2024-08-06 Philipp Bönninghausen , Rafael Uetz , Martin Henze

Many studies in vision tasks have aimed to create effective embedding spaces for single-label object prediction within an image. However, in reality, most objects possess multiple specific attributes, such as shape, color, and length, with…

计算机视觉与模式识别 · 计算机科学 2023-07-26 Chull Hwan Song , Taebaek Hwang , Jooyoung Yoon , Shunghyun Choi , Yeong Hyeon Gu

Advanced driver assistance systems (ADAS) play an important role in modern automotive intelligence, significantly enhancing vehicle safety and stability. The performance of ADAS critically relies on accurate and reliable vehicle state…

系统与控制 · 电气工程与系统科学 2026-05-26 Tianyi Wang , Tianyi Zeng , Zimo Zeng , Feiyang Zhang , Yujin Wang , Xiangyu Li , Yiming Xu , Sikai Chen , Junfeng Jiao , Christian Claudel , Xinbo Chen

Bioacoustics, the study of animal sounds, offers a non-invasive method to monitor ecosystems. Extracting embeddings from audio-pretrained deep learning (DL) models without fine-tuning has become popular for obtaining bioacoustic features…

声音 · 计算机科学 2025-08-15 Chenggang Chen , Zhiyu Yang

Identifying interacting partners from two sets of protein sequences has important applications in computational biology. Interacting partners share similarities across species due to their common evolutionary history, and feature…

生物大分子 · 定量生物学 2024-12-31 Umberto Lupo , Damiano Sgarbossa , Martina Milighetti , Anne-Florence Bitbol

Large-scale datasets have been pivotal to the advancements of deep learning models in recent years, but training on such large datasets invariably incurs substantial storage and computational overhead. Meanwhile, real-world datasets often…

计算机视觉与模式识别 · 计算机科学 2025-06-23 Suorong Yang , Peng Ye , Wanli Ouyang , Dongzhan Zhou , Furao Shen

The precise prediction of molecular properties is essential for advancements in drug development, particularly in virtual screening and compound optimization. The recent introduction of numerous deep learning-based methods has shown…

机器学习 · 计算机科学 2024-07-01 Taojie Kuang , Pengfei Liu , Zhixiang Ren

Multimodal deep learning harnesses diverse imaging modalities, such as MRI sequences, to enhance diagnostic accuracy in medical imaging. A key challenge is determining the optimal timing for integrating these modalities-specifically,…

计算机视觉与模式识别 · 计算机科学 2026-02-16 Valerio Guarrasi , Klara Mogensen , Sara Tassinari , Sara Qvarlander , Paolo Soda

Current deepfake detection models achieve state-of-the-art performance on pristine academic datasets but suffer severe spatial attention drift under real-world compound degradations, such as blurring and severe lossy compression. To address…

计算机视觉与模式识别 · 计算机科学 2026-04-29 Minh-Khoa Le-Phan , Minh-Hoang Le , Trong-Le Do , Minh-Triet Tran

Fitting nonlinear dynamical models to sparse and noisy observations is fundamentally challenging. Identifying dynamics requires data assimilation (DA) to estimate system states, but DA requires an accurate dynamical model. To break this…

机器学习 · 计算机科学 2024-09-12 Vadim Zinchenko , David S. Greenberg

Simultaneous segmentation of multiple organs from different medical imaging modalities is a crucial task as it can be utilized for computer-aided diagnosis, computer-assisted surgery, and therapy planning. Thanks to the recent advances in…

计算机视觉与模式识别 · 计算机科学 2021-09-16 Saeid Asgari Taghanaki , Yefeng Zheng , S. Kevin Zhou , Bogdan Georgescu , Puneet Sharma , Daguang Xu , Dorin Comaniciu , Ghassan Hamarneh

We study optimal covariate balance for causal inferences from observational data when rich covariates and complex relationships necessitate flexible modeling with neural networks. Standard approaches such as propensity weighting and…

机器学习 · 统计学 2018-02-16 Nathan Kallus

Power Delay Profile (PDP) plays a crucial role in wireless communications, providing information on multipath propagation and signal strength variations over time. Accurate detection of peaks within PDP is essential to identify dominant…

信号处理 · 电气工程与系统科学 2026-03-23 Ondrej Zeleny , Radek Zavorka , Ales Prokes , Tomas Fryza , Jaroslaw Wojtun , Jan M. Kelner , Cezary Ziolkowski , Aniruddha Chandra

Multimodal learning often grapples with the challenge of low-quality data, which predominantly manifests as two facets: modality imbalance and noisy corruption. While these issues are often studied in isolation, we argue that they share a…

计算机视觉与模式识别 · 计算机科学 2026-05-06 Xun Jiang , Yufan Gu , Disen Hu , Yuqing Hou , Yazhou Yao , Fumin Shen , Heng Tao Shen , Xing Xu

Ultrasound technology enables safe, non-invasive imaging of dynamic tissue behavior, making it a valuable tool in medicine, biomechanics, and sports science. However, accurately tracking tissue motion in B-mode ultrasound remains…

计算机视觉与模式识别 · 计算机科学 2025-07-22 Praneeth Namburi , Roger Pallarès-López , Jessica Rosendorf , Duarte Folgado , Brian W. Anthony

Acoustic sensing manifests great potential in various applications that encompass health monitoring, gesture interface and imaging by leveraging the speakers and microphones on smart devices. However, in ongoing research and development in…

声音 · 计算机科学 2025-09-16 Yin Li , Bo Liu , Rajalakshmi Nanadakumar

Deep Metric Learning (DML) methods aim at learning an embedding space in which distances are closely related to the inherent semantic similarity of the inputs. Previous studies have shown that popular benchmark datasets often contain…

计算机视觉与模式识别 · 计算机科学 2023-11-02 Oriol Barbany , Xiaofan Lin , Muhammet Bastan , Arnab Dhua

Osteoporosis is a common condition that increases fracture risk, especially in older adults. Early diagnosis is vital for preventing fractures, reducing treatment costs, and preserving mobility. However, healthcare providers face challenges…

In this work, we study whether enforcing strict compositional structure in sequence embeddings yields meaningful geometric organization when applied to protein-protein interaction networks. Using Event2Vec, an additive sequence embedding…

机器学习 · 计算机科学 2026-04-02 Antonin Sulc