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相关论文: Tx-LLM: A Large Language Model for Therapeutics

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Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

计算与语言 · 计算机科学 2024-05-27 Nicholas J Dobbins

Pre-trained LLMs have demonstrated substantial capabilities across a range of conventional natural language processing (NLP) tasks, such as summarization and entity recognition. In this paper, we explore the application of LLMs in the…

定量方法 · 定量生物学 2024-08-14 Kamyar Zeinalipour , Neda Jamshidi , Monica Bianchini , Marco Maggini , Marco Gori

The recent progress of large language models (LLMs), including ChatGPT and GPT-4, in comprehending and responding to human instructions has been remarkable. Nevertheless, these models typically perform better in English and have not been…

计算与语言 · 计算机科学 2023-04-18 Honglin Xiong , Sheng Wang , Yitao Zhu , Zihao Zhao , Yuxiao Liu , Linlin Huang , Qian Wang , Dinggang Shen

Large language models (LLMs) are widely applied in various natural language processing tasks such as question answering and machine translation. However, due to the lack of labeled data and the difficulty of manual annotation for…

人工智能 · 计算机科学 2026-05-27 Xuan Lin , Long Chen , Yile Wang , Yangyang Chen , Xiangxiang Zeng

Analyzing vast textual data and summarizing key information from electronic health records imposes a substantial burden on how clinicians allocate their time. Although large language models (LLMs) have shown promise in natural language…

Protein language models (PLMs) have advanced computational protein science through large-scale pretraining and scalable architectures. In parallel, reinforcement learning (RL) has broadened exploration and enabled precise multi-objective…

The advent of Large Language Models (LLMs) has drastically enhanced dialogue systems. However, comprehensively evaluating the dialogue abilities of LLMs remains a challenge. Previous benchmarks have primarily focused on single-turn…

计算与语言 · 计算机科学 2024-11-06 Ge Bai , Jie Liu , Xingyuan Bu , Yancheng He , Jiaheng Liu , Zhanhui Zhou , Zhuoran Lin , Wenbo Su , Tiezheng Ge , Bo Zheng , Wanli Ouyang

Augmenting large language models (LLMs) with external tools has emerged as a promising approach to extend their utility, enabling them to solve practical tasks. Previous methods manually parse tool documentation and create in-context…

计算与语言 · 计算机科学 2025-03-05 Zhengliang Shi , Shen Gao , Lingyong Yan , Yue Feng , Xiuyi Chen , Zhumin Chen , Dawei Yin , Suzan Verberne , Zhaochun Ren

The exponential growth of text-based data in domains such as healthcare, education, and social sciences has outpaced the capacity of traditional qualitative analysis methods, which are time-intensive and prone to subjectivity. Large…

New medical treatment development requires multiple phases of clinical trials. Despite the significant human and financial costs of bringing a drug to market, less than 20% of drugs in testing will make it from the first phase to final…

计算与语言 · 计算机科学 2024-08-21 Michael Reinisch , Jianfeng He , Chenxi Liao , Sauleh Ahmad Siddiqui , Bei Xiao

Time series analysis is pivotal in domains like financial forecasting and biomedical monitoring, yet traditional methods are constrained by limited nonlinear feature representation and long-term dependency capture. The emergence of Large…

机器学习 · 计算机科学 2025-06-16 Feifei Shi , Xueyan Yin , Kang Wang , Wanyu Tu , Qifu Sun , Huansheng Ning

The rapid evolution of large language models (LLMs) holds promise for reforming the methodology of spatio-temporal data mining. However, current works for evaluating the spatio-temporal understanding capability of LLMs are somewhat limited…

计算与语言 · 计算机科学 2024-06-28 Wenbin Li , Di Yao , Ruibo Zhao , Wenjie Chen , Zijie Xu , Chengxue Luo , Chang Gong , Quanliang Jing , Haining Tan , Jingping Bi

The shortage of clinical workforce presents significant challenges in mental healthcare, limiting access to formal diagnostics and services. We aim to tackle this shortage by integrating a customized large language model (LLM) into the…

计算与语言 · 计算机科学 2025-05-02 Sichang Tu , Abigail Powers , Natalie Merrill , Negar Fani , Sierra Carter , Stephen Doogan , Jinho D. Choi

Recently, tool learning with large language models (LLMs) has emerged as a promising paradigm for augmenting the capabilities of LLMs to tackle highly complex problems. Despite growing attention and rapid advancements in this field, the…

计算与语言 · 计算机科学 2024-11-05 Changle Qu , Sunhao Dai , Xiaochi Wei , Hengyi Cai , Shuaiqiang Wang , Dawei Yin , Jun Xu , Ji-Rong Wen

Recent advancements in large language models (LLMs) have demonstrated strong potential for enabling domain-specific intelligence. In this work, we present our vision for building an AI-powered chemical brain, which frames chemical…

Large language models (LLMs) have achieved remarkable performance on diverse benchmarks, yet existing evaluation practices largely rely on coarse summary metrics that obscure underlying reasoning abilities. In this work, we propose novel…

统计方法学 · 统计学 2026-03-17 Jia Liu , Zhiyu Xu , Yuqi Gu

Given the great success of large language models (LLMs) across various tasks, in this paper, we introduce LLM-ST, a novel and effective speech translation model constructed upon a pre-trained LLM. By integrating the large language model…

计算与语言 · 计算机科学 2023-12-22 Zhichao Huang , Rong Ye , Tom Ko , Qianqian Dong , Shanbo Cheng , Mingxuan Wang , Hang Li

Large language models (LLMs) have shown to be valuable tools for tackling process mining tasks. Existing studies report on their capability to support various data-driven process analyses and even, to some extent, that they are able to…

数据库 · 计算机科学 2025-05-01 Adrian Rebmann , Fabian David Schmidt , Goran Glavaš , Han van der Aa

Large language models (LLMs) with billions of parameters and pretrained on massive amounts of data are now capable of near or better than state-of-the-art performance in a variety of downstream natural language processing tasks. Neural…

计算与语言 · 计算机科学 2024-07-08 Victor Agostinelli , Max Wild , Matthew Raffel , Kazi Ahmed Asif Fuad , Lizhong Chen

The high incidence and mortality rates associated with respiratory diseases underscores the importance of early screening. Machine learning models can automate clinical consultations and auscultation, offering vital support in this area.…

机器学习 · 计算机科学 2024-10-10 Yuwei Zhang , Tong Xia , Aaqib Saeed , Cecilia Mascolo