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A general topic of current interest is the analysis of diffusion problems in singularly perturbed domains with small interior targets or traps (the narrow capture problem). One major application is to intracellular diffusion, where the…

统计力学 · 物理学 2022-04-13 Paul C. Bressloff

The cellular uptake of self-propelled nanoparticles (NPs) or viruses, usually nonspherical, by cell membrane is crucial in many biological processes. In this study, using Onsager variational principle, we obtain a general wrapping equation…

软凝聚态物质 · 物理学 2023-01-16 Ke Xiao , Rui Ma , Chen-Xu Wu

We perform molecular dynamics simulations to understand the translational and rotational diffusion of Janus nanoparticles at the interface between two immiscible fluids. Considering spherical particles with different affinity to fluid…

流体动力学 · 物理学 2016-05-04 Hossein Rezvantalab , German Drazer , Shahab Shojaei-Zadeh

In 1977 Berg & Purcell published a landmark paper entitled "Physics of Chemoreception" which examined how a bacterium can sense a chemical attractant in the fluid surrounding it. At small scales the attractant molecules move by Brownian…

偏微分方程分析 · 数学 2017-07-18 Andrew J. Bernoff , Alan E. Lindsay

We study light absorption by a dipolar absorber in a given environment, which can be a nanoantenna or any complex inhomogeneous medium. From first-principle calculations, we derive an upper bound for the absorption, which decouples the…

Advances in nanotechnology lead to an increasing interest in how nanoparticles interact with biomembranes. Nanoparticles are wrapped spontaneously by biomembranes if the adhesive interactions between the particles and membranes compensate…

亚细胞过程 · 定量生物学 2016-09-16 Michael Raatz , Thomas R. Weikl

The optically induced oscillatory response of a spherical two-component, shell-core structured, nanoparticle by nodeless elastic vibrations of soft peripheral shell against hard and dynamically immobile inner core is considered. The…

软凝聚态物质 · 物理学 2009-11-13 S. I. Bastrukov , P. -Y. Lai , I. V. Molodtsova , H. -K. Chang , D. V. Podgainy

The dispersive spreading of microscopic particles in shear flows is influenced both by advection and thermal motion. At the nanoscale, interactions between such particles and their confining boundaries become unavoidable. We address the…

软凝聚态物质 · 物理学 2023-02-01 Alexandre Vilquin , Vincent Bertin , Elie Raphaël , David S Dean , Thomas Salez , Joshua D. McGraw

We determine the asymptotic spreading speed of an invasive species, which invades the territory of a native competitor, governed by a diffusive competition model with a free boundary in a spherically symmetric setting. This free boundary…

偏微分方程分析 · 数学 2015-06-19 Yihong Du , Mingxin Wang , Maolin Zhou

Chemical reactions inside cells are generally considered to happen within fixed-size compartments. Needless to say, cells and their compartments are highly dynamic. Thus, such stringent assumptions may not reflect biochemical reality, and…

定量方法 · 定量生物学 2016-02-17 Atiyo Ghosh , Tatiana T. Marquez-Lago

We consider processes that coincide with a given diffusion process except on the boundaries of a finite collection of domains. The behavior on each of the boundaries is asymmetric: the process is much more likely to enter the interior of…

概率论 · 数学 2020-03-18 Mark Freidlin , Leonid Koralov

The problem of the time required for a diffusing molecule, within a large bounded domain, to first locate a small target is prevalent in biological modeling. Here we study this problem for a small spherical target. We develop uniform in…

生物物理 · 物理学 2013-08-06 Samuel A. Isaacson , Jay Newby

We investigate the long time behavior of a passive particle evolving in a one-dimensional diffusive random environment, with diffusion constant $D$. We consider two cases: (a) The particle is pulled forward by a small external constant…

统计力学 · 物理学 2018-04-16 François Huveneers

How many times a diffusing molecule can permeate across a membrane or be adsorbed on a substrate? We employ the encounter-based approach to find the statistics of adsorption or permeation events for molecular diffusion in a general…

化学物理 · 物理学 2025-07-15 Denis S. Grebenkov

Using molecular dynamics simulations, we show that an asymmetrically shaped nanoparticle in dilute solution possesses a spontaneously curved trajectory within finite time interval, instead of the generally expected random walk. This…

软凝聚态物质 · 物理学 2016-10-13 Nan Sheng , YuSong Tu , Pan Guo , RongZheng Wan , ZuoWei Wang , HaiPing Fang

This paper considers membranes of globular structure in the framework of the cell model technique. Coupled micropolar and Brinkman-type equations are used to model the flow of micropolar fluid through a spherical cell, consisting of solid…

流体动力学 · 物理学 2020-05-05 D. Yu. Khanukaeva

In the present work, the behavior of vacancy pore inside of spherical particle is investigated. On the assumption of quasistationarity of diffusion fluxes, the nonlinear equation set was obtained analytically, that describes completely pore…

介观与纳米尺度物理 · 物理学 2018-09-19 V. V. Yanovsky , M. I. Kopp , M. A. Ratner

Cells offer numerous inspiring examples where proteins and membranes combine to form complex structures that are key to intracellular compartmentalization, cargo transport, and specialization of cell morphology. Despite this wealth of…

The short diffusion lengths in insertion battery nanoparticles render the capacitive behavior of bounded diffusion, which is rarely observable with conventional larger particles, now accessible to impedance measurements. Coupled with…

化学物理 · 物理学 2012-05-31 J. Song , M. Z. Bazant

We study the time-harmonic scattering by a heterogeneous object covered with a thin layer of randomly distributed sound-soft nanoparticles. The size of the particles, their distance between each other and the layer's thickness are all of…

偏微分方程分析 · 数学 2026-01-13 Amandine Boucart , Sonia Fliss , Laure Giovangigli