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Understanding how genetically encoded rules drive and guide complex neuronal growth processes is essential to comprehending the brain's architecture, and agent-based models (ABMs) offer a powerful simulation approach to further develop this…

计算工程、金融与科学 · 计算机科学 2024-05-24 Tobias Duswald , Lukas Breitwieser , Thomas Thorne , Barbara Wohlmuth , Roman Bauer

This chapter will appear in the forthcoming Handbook of Approximate Bayesian Computation (2018). Indirect inference (II) is a classical likelihood-free approach that pre-dates the main developments of ABC and relies on simulation from a…

统计计算 · 统计学 2018-03-07 Christopher C Drovandi

Estimating the predictive uncertainty of a Bayesian learning model is critical in various decision-making problems, e.g., reinforcement learning, detecting adversarial attack, self-driving car. As the model posterior is almost always…

机器学习 · 计算机科学 2021-02-16 Yufei Cui , Wuguannan Yao , Qiao Li , Antoni B. Chan , Chun Jason Xue

Over the past decade, the field of forensic science has received recommendations from the National Research Council of the U.S. National Academy of Sciences, the U.S. National Institute of Standards and Technology, and the U.S. President's…

应用统计 · 统计学 2020-01-08 Jessie Hendricks , Cedric Neumann

Approximate Bayesian computation is an established and popular method for likelihood-free inference with applications in many disciplines. The effectiveness of the method depends critically on the availability of well performing summary…

机器学习 · 统计学 2018-05-23 Prashant Singh , Andreas Hellander

Missing data is a recurrent issue in epidemiology where the infection process may be partially observed. Approximate Bayesian Computation, an alternative to data imputation methods such as Markov Chain Monte Carlo integration, is proposed…

应用统计 · 统计学 2010-08-31 Michael G. B. Blum , Viet Chi Tran

Bayesian inference typically requires the computation of an approximation to the posterior distribution. An important requirement for an approximate Bayesian inference algorithm is to output high-accuracy posterior mean and uncertainty…

统计理论 · 数学 2018-10-03 Jonathan H. Huggins , Trevor Campbell , Mikołaj Kasprzak , Tamara Broderick

Bayesian methods provide an elegant framework for estimating parameter posteriors and quantification of uncertainty associated with probabilistic models. However, they often suffer from slow inference times. To address this challenge,…

机器学习 · 计算机科学 2024-05-10 Piyush Tiwary , Kumar Shubham , Vivek V. Kashyap , Prathosh A. P

Bayesian models quantify uncertainty and facilitate optimal decision-making in downstream applications. For most models, however, practitioners are forced to use approximate inference techniques that lead to sub-optimal decisions due to…

机器学习 · 统计学 2019-09-12 Tomasz Kuśmierczyk , Joseph Sakaya , Arto Klami

Approximate Bayesian computation (ABC) provides us with a way to infer parameters of models, for which the likelihood function is not available, from an observation. Using ABC, which depends on many simulations from the considered model, we…

Models defined by stochastic differential equations (SDEs) allow for the representation of random variability in dynamical systems. The relevance of this class of models is growing in many applied research areas and is already a standard…

统计方法学 · 统计学 2014-08-06 Umberto Picchini

We consider the application of approximate Bayesian Computation (ABC) in the context of medical imaging data. We consider the parameter estimation of compartmental models in PET imaging analysis, and provide a simple ABC algorithm for its…

应用统计 · 统计学 2016-08-01 Y. Fan , S. R. Meikle , G. Angelis , A. Sitek

Approximate Bayesian Computation is widely used to infer the parameters of discrete-state continuous-time Markov networks. In this work, we focus on models that are governed by the Chemical Master Equation (the CME). Whilst originally…

定量方法 · 定量生物学 2020-01-10 Christopher Lester

Gibbs random fields (GRF) are polymorphous statistical models that can be used to analyse different types of dependence, in particular for spatially correlated data. However, when those models are faced with the challenge of selecting a…

In this paper, we address the challenge of Markov Chain Monte Carlo (MCMC) algorithms within the approximate Bayesian Computation (ABC) framework, which often get trapped in local optima due to their inherent local exploration mechanism. We…

统计计算 · 统计学 2025-12-16 Xuefei Cao , Shijia Wang , Yongdao Zhou

Stochastic systems in biology often exhibit substantial variability within and between cells. This variability, as well as having dramatic functional consequences, provides information about the underlying details of the system's behaviour.…

定量方法 · 定量生物学 2015-11-09 Iain G. Johnston

Many real-life problems are represented as a black-box, i.e., the internal workings are inaccessible or a closed-form mathematical expression of the likelihood function cannot be defined. For continuous random variables likelihood-free…

机器学习 · 统计学 2020-10-21 Ilze Amanda Auzina , Jakub M. Tomczak

We develop scalable methods for producing conformal Bayesian predictive intervals with finite sample calibration guarantees. Bayesian posterior predictive distributions, $p(y \mid x)$, characterize subjective beliefs on outcomes of…

统计方法学 · 统计学 2021-06-15 Edwin Fong , Chris Holmes

Approximate Bayesian computation allows for inference of complicated probabilistic models with intractable likelihoods using model simulations. The Markov chain Monte Carlo implementation of approximate Bayesian computation is often…

统计计算 · 统计学 2019-05-17 Matti Vihola , Jordan Franks

Simulation models often lack tractable likelihood functions, making likelihood-free inference methods indispensable. Approximate Bayesian computation generates likelihood-free posterior samples by comparing simulated and observed data…

统计方法学 · 统计学 2023-02-02 Joel Dyer , Patrick Cannon , Sebastian M Schmon
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