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We aim to generalize the results of a randomized controlled trial (RCT) to a target population with the help of some observational data. This is a problem of causal effect identification with multiple data sources. Challenges arise when the…

统计方法学 · 统计学 2022-06-15 Juha Karvanen

When engagement with a randomized trial is driven by factors that affect the outcome or when trial engagement directly affects the outcome independent of treatment, the average treatment effect among trial participants is unlikely to…

统计方法学 · 统计学 2019-06-27 Issa J. Dahabreh , James M. Robins , Sebastien J-P. A. Haneuse , Miguel A. Hernán

Randomized Controlled Trials (RCTs) are pivotal in generating internally valid estimates with minimal assumptions, serving as a cornerstone for researchers dedicated to advancing causal inference methods. However, extending these findings…

统计方法学 · 统计学 2024-05-28 Melody Y Huang , Harsh Parikh

Complementary features of randomized controlled trials (RCTs) and observational studies (OSs) can be used jointly to estimate the average treatment effect of a target population. We propose a calibration weighting estimator that enforces…

统计方法学 · 统计学 2022-02-16 Dasom Lee , Shu Yang , Lin Dong , Xiaofei Wang , Donglin Zeng , Jianwen Cai

Randomized controlled trials (RCTs) are increasingly prevalent in education research, and are often regarded as a gold standard of causal inference. Two main virtues of randomized experiments are that they (1) do not suffer from…

We argue that randomized controlled trials (RCTs) are special even among settings where average treatment effects are identified by a nonparametric unconfoundedness assumption. This claim follows from two results of Robins and Ritov (1997):…

统计方法学 · 统计学 2021-09-28 P. M. Aronow , James M. Robins , Theo Saarinen , Fredrik Sävje , Jasjeet Sekhon

Despite the increasing relevance of forecasting methods, causal implications of these algorithms remain largely unexplored. This is concerning considering that, even under simplifying assumptions such as causal sufficiency, the statistical…

While many areas of machine learning have benefited from the increasing availability of large and varied datasets, the benefit to causal inference has been limited given the strong assumptions needed to ensure identifiability of causal…

机器学习 · 计算机科学 2022-01-02 Wenshuo Guo , Serena Wang , Peng Ding , Yixin Wang , Michael I. Jordan

Randomized controlled trials (RCTs) yield internally valid causal effect estimates, but generalizing these results to target populations with different characteristics requires an untestable selection ignorability assumption: conditional on…

统计方法学 · 统计学 2026-03-31 Amir Asiaee , Samhita Pal , Jared D. Huling

Causal inference from observational data can be viewed as a missing data problem arising from a hypothetical population-scale randomized trial matched to the observational study. This links a target trial protocol with a corresponding…

统计方法学 · 统计学 2022-07-27 Andrew Yiu , Edwin Fong , Stephen Walker , Chris Holmes

Randomized Controlled Trials (RCTs) represent a gold standard when developing policy guidelines. However, RCTs are often narrow, and lack data on broader populations of interest. Causal effects in these populations are often estimated using…

机器学习 · 计算机科学 2023-03-07 Zeshan Hussain , Michael Oberst , Ming-Chieh Shih , David Sontag

The ability to generalize experimental results from randomized control trials (RCTs) across locations is crucial for informing policy decisions in targeted regions. Such generalization is often hindered by the lack of identifiability due to…

计量经济学 · 经济学 2021-12-10 Xinkun Nie , Guido Imbens , Stefan Wager

Randomized controlled trials (RCT's) allow researchers to estimate causal effects in an experimental sample with minimal identifying assumptions. However, to generalize or transport a causal effect from an RCT to a target population,…

统计方法学 · 统计学 2022-02-08 Melody Huang

Randomized trials are considered the gold standard for estimating causal effects. Trial findings are often used to inform policy and programming efforts, yet their results may not generalize well to a relevant target population due to…

For obtaining causal inferences that are objective, and therefore have the best chance of revealing scientific truths, carefully designed and executed randomized experiments are generally considered to be the gold standard. Observational…

应用统计 · 统计学 2008-11-12 Donald B. Rubin

Scientists frequently generalize population level causal quantities such as average treatment effect from a source population to a target population. When the causal effects are heterogeneous, differences in subject characteristics between…

统计方法学 · 统计学 2023-06-16 Rui Chen , Guanhua Chen , Menggang Yu

While statistics and machine learning offers numerous methods for ensuring generalization, these methods often fail in the presence of adaptivity---the common practice in which the choice of analysis depends on previous interactions with…

机器学习 · 计算机科学 2018-06-19 Kobbi Nissim , Adam Smith , Thomas Steinke , Uri Stemmer , Jonathan Ullman

When assessing causal effects, determining the target population to which the results are intended to generalize is a critical decision. Randomized and observational studies each have strengths and limitations for estimating causal effects…

统计方法学 · 统计学 2022-10-21 Irina Degtiar , Sherri Rose

Randomized controlled trials (RCTs) provide strong internal validity compared with observational studies. However, selection bias threatens the external validity of randomized trials. Thus, RCT results may not apply to either broad public…

统计方法学 · 统计学 2017-04-26 Ziyue Chen , Eloise Kaizar

When treatment effect modifiers influence the decision to participate in a randomized trial, the average treatment effect in the population represented by the randomized individuals will differ from the effect in other populations. In this…

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