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Unsupervised anomaly detection in medical imaging aims to detect and localize arbitrary anomalies without requiring annotated anomalous data during training. Often, this is achieved by learning a data distribution of normal samples and…

计算机视觉与模式识别 · 计算机科学 2023-01-06 Carsten T. Lüth , David Zimmerer , Gregor Koehler , Paul F. Jaeger , Fabian Isensee , Jens Petersen , Klaus H. Maier-Hein

Diffusion models have shown superior performance on unsupervised anomaly detection tasks. Since trained with normal data only, diffusion models tend to reconstruct normal counterparts of test images with certain noises added. However, these…

计算机视觉与模式识别 · 计算机科学 2024-09-10 Hang Yao , Ming Liu , Haolin Wang , Zhicun Yin , Zifei Yan , Xiaopeng Hong , Wangmeng Zuo

Self-supervised instance discrimination is an effective contrastive pretext task to learn feature representations and address limited medical image annotations. The idea is to make features of transformed versions of the same images similar…

计算机视觉与模式识别 · 计算机科学 2022-11-17 Yejia Zhang , Xinrong Hu , Nishchal Sapkota , Yiyu Shi , Danny Z. Chen

Robust and accurate detection and segmentation of heterogenous tumors appearing in different anatomical organs with supervised methods require large-scale labeled datasets covering all possible types of diseases. Due to the unavailability…

计算机视觉与模式识别 · 计算机科学 2023-05-23 Mehdi Astaraki , Francesca De Benetti , Yousef Yeganeh , Iuliana Toma-Dasu , Örjan Smedby , Chunliang Wang , Nassir Navab , Thomas Wendler

The scarcity and complexity of voxel-level annotations in 3D medical imaging present significant challenges, particularly due to the domain gap between labeled datasets from well-resourced centers and unlabeled datasets from less-resourced…

计算机视觉与模式识别 · 计算机科学 2024-08-13 Haifan Gong , Yitao Wang , Yihan Wang , Jiashun Xiao , Xiang Wan , Haofeng Li

Anomalies are by definition rare, thus labeled examples are very limited or nonexistent, and likely do not cover unforeseen scenarios. Unsupervised learning methods that don't necessarily encounter anomalies in training would be immensely…

计算机视觉与模式识别 · 计算机科学 2020-06-23 Louise Naud , Alexander Lavin

T2 hyperintensities in spinal cord MR images are crucial biomarkers for conditions such as degenerative cervical myelopathy. However, current clinical diagnoses primarily rely on manual evaluation. Deep learning methods have shown promise…

图像与视频处理 · 电气工程与系统科学 2025-03-18 Qi Zhang , Xiuyuan Chen , Ziyi He , Kun Wang , Lianming Wu , Hongxing Shen , Jianqi Sun

An assumption-free automatic check of medical images for potentially overseen anomalies would be a valuable assistance for a radiologist. Deep learning and especially Variational Auto-Encoders (VAEs) have shown great potential in the…

机器学习 · 计算机科学 2019-07-12 David Zimmerer , Fabian Isensee , Jens Petersen , Simon Kohl , Klaus Maier-Hein

The primary goal of this work is to study the effectiveness of an unsupervised domain adaptation approach for various applications such as binary classification and anomaly detection in the context of Alzheimer's disease (AD) detection for…

图像与视频处理 · 电气工程与系统科学 2022-12-27 Pranath Reddy

Contrastive analysis (CA) refers to the exploration of variations uniquely enriched in a target dataset as compared to a corresponding background dataset generated from sources of variation that are irrelevant to a given task. For example,…

机器学习 · 计算机科学 2023-10-31 Ethan Weinberger , Ian Covert , Su-In Lee

Confounding pathology with normal anatomical variation remains a significant challenge in unsupervised medical-image anomaly detection, resulting in numerous false positives. To enhance integration of healthy variation, we augment the…

定量方法 · 定量生物学 2026-03-09 P. Bilha Githinji , Xi Yuan , Ijaz Gul , Lian Zhang , Jinhao Xu , Zhenglin Chen , Peiwu Qin , Dongmei Yu

Purpose. Brain Magnetic Resonance Images (MRIs) are essential for the diagnosis of neurological diseases. Recently, deep learning methods for unsupervised anomaly detection (UAD) have been proposed for the analysis of brain MRI. These…

图像与视频处理 · 电气工程与系统科学 2021-09-15 Marcel Bengs , Finn Behrendt , Julia Krüger , Roland Opfer , Alexander Schlaefer

Deep learning models are widely employed in safety-critical applications yet remain susceptible to adversarial attacks -- imperceptible perturbations that can significantly degrade model performance. Conventional defense mechanisms…

计算机视觉与模式识别 · 计算机科学 2025-10-28 Eylon Mizrahi , Raz Lapid , Moshe Sipper

Recent advances in diffusion models have spurred research into their application for Reconstruction-based unsupervised anomaly detection. However, these methods may struggle with maintaining structural integrity and recovering the…

计算机视觉与模式识别 · 计算机科学 2025-03-27 Farzad Beizaee , Gregory A. Lodygensky , Christian Desrosiers , Jose Dolz

For the Facial Action Unit (AU) detection task, accurately capturing the subtle facial differences between distinct AUs is essential for reliable detection. Additionally, AU detection faces challenges from class imbalance and the presence…

计算机视觉与模式识别 · 计算机科学 2025-12-01 Ziqiao Shang , Bin Liu , Fengmao Lv , Fei Teng , Tianrui Li , Lan-Zhe Guo

Deep learning models trained on medical images from a source domain (e.g. imaging modality) often fail when deployed on images from a different target domain, despite imaging common anatomical structures. Deep unsupervised domain adaptation…

图像与视频处理 · 电气工程与系统科学 2019-08-14 Cheng Ouyang , Konstantinos Kamnitsas , Carlo Biffi , Jinming Duan , Daniel Rueckert

Ultrasonography is an essential tool in mid-pregnancy for assessing fetal development, appreciated for its non-invasive and real-time imaging capabilities. Yet, the interpretation of ultrasound images is often complicated by acoustic…

图像与视频处理 · 电气工程与系统科学 2024-07-23 Hanna Mykula , Lisa Gasser , Silvia Lobmaier , Julia A. Schnabel , Veronika Zimmer , Cosmin I. Bercea

Anomaly detection (AD) aims at detecting abnormal samples that deviate from the expected normal patterns. Generally, it can be trained merely on normal data, without a requirement for abnormal samples, and thereby plays an important role in…

计算机视觉与模式识别 · 计算机科学 2025-02-20 Yu Cai , Weiwen Zhang , Hao Chen , Kwang-Ting Cheng

Anomaly detection in multivariate time series (MTS) is hindered by dynamic inter-variable dependencies and feature entanglement under spectral noise, and in practice, is further complicated by the absence of anomaly labels. Existing…

机器学习 · 计算机科学 2026-05-25 Yunhua Pei , Zixing Song , Jin Zheng , John Cartlidge

Unsupervised Anomaly detection (AD) requires building a notion of normalcy, distinguishing in-distribution (ID) and out-of-distribution (OOD) data, using only available ID samples. Recently, large gains were made on this task for the domain…

计算机视觉与模式识别 · 计算机科学 2022-03-22 Mohamed Yousef , Marcel Ackermann , Unmesh Kurup , Tom Bishop