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Understanding how neuronal networks reorganize in response to external stimuli and give rise to behavior is a central challenge in neuroscience and artificial intelligence. However, existing methods often fail to capture the evolving…

神经元与认知 · 定量生物学 2025-06-02 Moein Khajehnejad , Forough Habibollahi , Ahmad Khajehnejad , Chris French , Brett J. Kagan , Adeel Razi

The task of deducing three-dimensional molecular configurations from their two-dimensional graph representations holds paramount importance in the fields of computational chemistry and pharmaceutical development. The rapid advancement of…

生物大分子 · 定量生物学 2025-01-09 Bobin Yang , Jie Deng , Zhenghan Chen , Ruoxue Wu

Model-based design of experiments (MBDOE) is essential for efficient parameter estimation in nonlinear dynamical systems. However, conventional adaptive MBDOE requires costly posterior inference and design optimization between each…

机器学习 · 统计学 2026-03-25 Arno Strouwen , Sebastian Micluţa-Câmpeanu

Diffusion models have garnered significant attention since they can effectively learn complex multivariate Gaussian distributions, resulting in diverse, high-quality outcomes. They introduce Gaussian noise into training data and reconstruct…

计算机视觉与模式识别 · 计算机科学 2023-12-27 Vidya Prasad , Chen Zhu-Tian , Anna Vilanova , Hanspeter Pfister , Nicola Pezzotti , Hendrik Strobelt

We introduce MedCondDiff, a diffusion-based framework for multi-organ medical image segmentation that is efficient and anatomically grounded. The model conditions the denoising process on semantic priors extracted by a Pyramid Vision…

图像与视频处理 · 电气工程与系统科学 2025-12-02 Ruirui Huang , Jiacheng Li

Diffuse Large B-cell Lymphoma (DLBCL) is a lymphatic cancer involving one or more lymph nodes and extranodal sites. Its diagnostic and follow-up rely on Positron Emission Tomography (PET) and Computed Tomography (CT). After diagnosis, the…

Patlak model is widely used in 18F-FDG dynamic positron emission tomography (PET) imaging, where the estimated parametric images reveal important biochemical and physiology information. Because of better noise modeling and more information…

医学物理 · 物理学 2020-09-15 Nuobei Xie , Kuang Gong , Ning Guo , Zhixing Qin , Jianan Cui , Zhifang Wu , Huafeng Liu , Quanzheng Li

Generating realistic MRIs to accurately predict future changes in the structure of brain is an invaluable tool for clinicians in assessing clinical outcomes and analysing the disease progression at the patient level. However, current…

计算机视觉与模式识别 · 计算机科学 2025-09-04 Mattia Litrico , Francesco Guarnera , Mario Valerio Giuffrida , Daniele Ravì , Sebastiano Battiato

Positron Emission Tomography (PET) is an important molecular imaging tool widely used in medicine. Traditional PET systems rely on complete detector rings for full angular coverage and reliable data collection. However, incomplete-ring PET…

计算机视觉与模式识别 · 计算机科学 2026-05-26 Yeqi Fang , Rong Zhou

Recently, skeleton-based human action has become a hot research topic because the compact representation of human skeletons brings new blood to this research domain. As a result, researchers began to notice the importance of using RGB or…

计算机视觉与模式识别 · 计算机科学 2023-07-26 Yifan Jiang , Han Chen , Hanseok Ko

Diffusion models have demonstrated remarkable success in various domains, including molecular generation. However, conditional molecular generation remains a fundamental challenge due to an intrinsic trade-off between targeting specific…

机器学习 · 计算机科学 2024-11-04 Hojung Jung , Youngrok Park , Laura Schmid , Jaehyeong Jo , Dongkyu Lee , Bongsang Kim , Se-Young Yun , Jinwoo Shin

Medical image segmentation is crucial for clinical diagnosis and treatment planning. Traditional methods typically produce a single segmentation mask, failing to capture inherent uncertainty. Recent generative models enable the creation of…

计算机视觉与模式识别 · 计算机科学 2026-02-27 Huynh Trinh Ngoc , Toan Nguyen Hai , Ba Luong Son , Long Tran Quoc

We demonstrate a machine learning based approach which can learn the time-dependent electronic excitation dynamics of small molecules subjected to ion irradiation. Ensembles of recurrent neural networks are trained on data generated by…

化学物理 · 物理学 2024-09-24 Ethan P. Shapera , Cheng-Wei Lee

Machine learning is becoming increasingly important for nonlinear system identification, including dynamical systems with spatially distributed outputs. However, classical identification and forecasting approaches become markedly less…

系统与控制 · 电气工程与系统科学 2026-04-21 Achraf El Messaoudi , Noureddine Khaous , Karim Cherifi

Coarse-grained modeling in molecular simulations serves not only to extend accessible time and length scales beyond atomistic limits, but also to reduce high-dimensional chemical data to low-dimensional representations that expose the…

化学物理 · 物理学 2026-05-19 Michael N. Sakano , Alejandro Strachan

Accurate spectrum demand prediction is crucial for informed spectrum allocation, effective regulatory planning, and fostering sustainable growth in modern wireless communication networks. It supports governmental efforts, particularly those…

机器学习 · 计算机科学 2025-08-07 Amin Farajzadeh , Hongzhao Zheng , Sarah Dumoulin , Trevor Ha , Halim Yanikomeroglu , Amir Ghasemi

The aim of this paper is to discuss potential advances in PET kinetic models and direct reconstruction of kinetic parameters. As a prominent example we focus on a typical task in perfusion imaging and derive a system of…

最优化与控制 · 数学 2014-11-20 Louise Reips , Martin Burger , Ralf Engbers

Radiotherapy continues to become more precise and data dense, with current treatment regimens generating high frequency imaging and dosimetry streams ideally suited for AI driven temporal modeling to characterize how normal tissues evolve…

计算机视觉与模式识别 · 计算机科学 2026-02-24 Anvi Sud , Jialu Huang , Gregory R. Hart , Keshav Saxena , John Kim , Lauren Tressel , Jun Deng

To analyze the impacts of certain types of public health interventions we need to estimate the treatment effects and outcomes as these apply to heterogeneous open populations. Dynamically modifying populations containing risk groups that…

统计方法学 · 统计学 2019-10-14 Aditi Shenvi , Jim Q. Smith

Tensor decomposition is an important tool for multiway data analysis. In practice, the data is often sparse yet associated with rich temporal information. Existing methods, however, often under-use the time information and ignore the…

机器学习 · 计算机科学 2023-10-31 Zheng Wang , Shikai Fang , Shibo Li , Shandian Zhe