相关论文: CAVACHON: a hierarchical variational autoencoder t…

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

Despite recent molecular technique improvements, biological knowledge remains incomplete. Reasoning on living systems hence implies to integrate heterogeneous and partial informations. Although current investigations successfully focus on…

Multimodal learning typically relies on the assumption that all modalities are fully available during both the training and inference phases. However, in real-world scenarios, consistently acquiring complete multimodal data presents…

Recent works in multimodal recommendations, which leverage diverse modal information to address data sparsity and enhance recommendation accuracy, have garnered considerable interest. Two key processes in multimodal recommendations are…

Single-cell technologies enable comprehensive profiling of diverse immune cell-types through the measurement of multiple genes or proteins per individual cell. In order to translate immune signatures assayed from blood or tissue into…

Efficient similarity retrieval from large-scale multimodal database is pervasive in modern search engines and social networks. To support queries across content modalities, the system should enable cross-modal correlation and…

Persistent homology is a powerful tool for characterizing the topology of a data set at various geometric scales. When applied to the description of molecular structures, persistent homology can capture the multiscale geometric features and…

Histopathology remains the gold standard for cancer diagnosis and prognosis. With the advent of transcriptome profiling, multi-modal learning combining transcriptomics with histology offers more comprehensive information. However, existing…

We propose a Bayesian latent variable model to estimate covariate-assisted dependence structures across multiple modalities of multivariate data that may be observed asynchronously. This setting commonly arises in longitudinal biomedical…

Gaussian graphical models typically assume a homogeneous structure across all subjects, which is often restrictive in applications. In this article, we propose a weighted pseudo-likelihood approach for graphical modeling which allows…

Medical datasets and especially biobanks, often contain extensive tabular data with rich clinical information in addition to images. In practice, clinicians typically have less data, both in terms of diversity and scale, but still wish to…

Artificial Intelligence Virtual Cells (AIVCs) aim to learn executable, decision-relevant models of cell state from multimodal, multiscale measurements. Recent studies have introduced single-cell and spatial foundation models, improved…

Multimodal data modeling has emerged as a powerful approach in clinical research, enabling the integration of diverse data types such as imaging, genomics, wearable sensors, and electronic health records. Despite its potential to improve…

We present CardiacGen, a Deep Learning framework for generating synthetic but physiologically plausible cardiac signals like ECG. Based on the physiology of cardiovascular system function, we propose a modular hierarchical generative model…

We propose cross-modal attentive connections, a new dynamic and effective technique for multimodal representation learning from wearable data. Our solution can be integrated into any stage of the pipeline, i.e., after any convolutional…

Most current audio-visual emotion recognition models lack the flexibility needed for deployment in practical applications. We envision a multimodal system that works even when only one modality is available and can be implemented…

Heterogeneous, mixed type datasets including both continuous and categorical variables are ubiquitous, and enriches data analysis by allowing for more complex relationships and interactions to be modelled. Mixture models offer a flexible…

Multimodal survival prediction, a crucial yet challenging task, demands the integration of multimodal medical data (\eg Whole Slide Images (WSIs) and Genomic Profiles) to achieve accurate prognostic modeling. Given the inherent…

Deep generative models often perform poorly in real-world applications due to the heterogeneity of natural data sets. Heterogeneity arises from data containing different types of features (categorical, ordinal, continuous, etc.) and…

We present a general framework, the coupled compound Poisson factorization (CCPF), to capture the missing-data mechanism in extremely sparse data sets by coupling a hierarchical Poisson factorization with an arbitrary data-generating model.…