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A critical question in epidemic control concerns the minimal requirements for a vaccination campaign to effectively halt a contagion process. However, control measures can inadvertently trigger resurgence dynamics, driven by a reservoir of…

物理与社会 · 物理学 2025-02-04 Piergiorgio Castioni , Alex Arenas

Finding optimal policies to reduce the morbidity and mortality of the ongoing pandemic is a top public health priority. Using a compartmental model with age structure and vaccination status, we examined the effect of age specific scheduling…

种群与进化 · 定量生物学 2012-02-29 Diána Knipl , Gergely Röst

We examine here the effects of recurrent vaccination and waning immunity on the establishment of an endemic equilibrium in a population. An individual-based model that incorporates memory effects for transmission rate during infection and…

种群与进化 · 定量生物学 2024-11-22 Félix Foutel-Rodier , Arthur Charpentier , Hélène Guérin

Since early 2020, the world has been dealing with a raging pandemic outbreak: COVID-19. A year later, vaccines have become accessible, but in limited quantities, so that governments needed to devise a strategy to decide which part of the…

种群与进化 · 定量生物学 2022-04-13 Sander Tonkens , Paul de Klaver , Mauro Salazar

Motivated by the increasing number of COVID-19 cases that have been observed in many countries after the vaccination and relaxation of non-pharmaceutical interventions, we propose a mathematical model on time-varying networks for the spread…

动力系统 · 数学 2022-03-09 Kathinka Frieswijk , Lorenzo Zino , Ming Cao

Most vaccines require multiple doses, the first to induce recognition and antibody production and subsequent doses to boost the primary response and achieve optimal protection. We show that properly prioritizing the administration of first…

The spread of infectious disease is strongly influenced by social dynamics. In addition to infection risk, individuals vaccination decisions depend on prevailing social behavior: high infection levels and widespread vaccination can increase…

种群与进化 · 定量生物学 2026-04-17 Xinxuan Wang , Youngmin Park , Bryce Morsky

The potential waning of the vaccination immunity to COVID-19 could pose threats to public health, as it is tenable that the timing of such waning would synchronize with the near-complete restoration of normalcy. Should also testing be…

This paper investigates the effects of vaccination on the dynamics of infectious disease, which is spreading in a population concurrently with awareness. The model considers contributions to the overall awareness from a global information…

定量方法 · 定量生物学 2018-05-14 G. O. Agaba , Y. N. Kyrychko , K. B. Blyuss

Opposition to vaccination has long been a non-negligible public health phenomenon resulted from people's varied perceptions toward vaccination (e.g., vaccine-phobia). This paper investigates the voluntary vaccination behavior of a…

物理与社会 · 物理学 2019-09-04 Liqun Lu , Yanfeng Ouyang

In the face of serious infectious diseases, governments endeavour to implement containment measures such as public vaccination at a macroscopic level. Meanwhile, individuals tend to protect themselves by avoiding contacts with infections at…

物理与社会 · 物理学 2016-10-20 Xiao-Long Peng , Xin-Jian Xu , Michael Small , Xinchu Fu , Zhen Jin

Optimization of vaccine allocations among different segments of a heterogeneous population is important for enhancing the effectiveness of vaccination campaigns in reducing the burden of epidemics. Intuitively, it would seem that…

定量方法 · 定量生物学 2022-12-01 Nir Gavish , Guy Katriel

Efficient testing and vaccination protocols are critical aspects of epidemic management. To study the optimal allocation of limited testing and vaccination resources in a heterogeneous contact network of interacting susceptible, recovered,…

种群与进化 · 定量生物学 2026-05-12 Mingtao Xia , Lucas Böttcher , Tom Chou

Given limited supply of approved vaccines and constrained medical resources, design of a vaccination strategy to control a pandemic is an economic problem. We use time-series and panel methods with real-world country-level data to estimate…

综合经济学 · 经济学 2022-01-19 Dongwoo Kim , Young Jun Lee

We consider optimal vaccination protocol where the vaccine is in short supply. In this case, disease extinction results from a large and rare fluctuation. We show that the probability of such fluctuation can be exponentially increased by…

种群与进化 · 定量生物学 2013-05-29 M. Khasin , M. I. Dykman , B. Meerson

Motivated by massive outbreaks of COVID-19 that occurred even in populations with high vaccine uptake, we propose a novel multi-population temporal network model for the spread of recurrent epidemic diseases. We study the effect of human…

动力系统 · 数学 2022-09-19 Kathinka Frieswijk , Lorenzo Zino , Ming Cao

Qatar has undergone distinct waves of COVID-19 infections, compounded by the emergence of variants, posing additional complexities. This research uniquely delves into the varied efficacy of existing vaccines and the pivotal role of…

应用统计 · 统计学 2023-12-29 Elizabeth Amona , Indranil Sahoo , Edward Boone , Ryad Ghanam

Understanding dynamics of an infectious disease helps in designing appropriate strategies for containing its spread in a population. Recent mathematical models are aimed at studying dynamics of some specific types of infectious diseases. In…

动力系统 · 数学 2015-02-05 P. Raja Sekhara Rao , M. Naresh Kumar

Vaccination is essential for the management of infectious diseases, many of which continue to pose devastating public health and economic challenges across the world. However, many vaccines are imperfect having only a partial protective…

种群与进化 · 定量生物学 2022-08-04 Hetsron L. Nyandjo-Bamen , Jean Marie Ntaganda , Aurelien Tellier , Olivier Menoukeu-Pamen

The pursuit of strategies that minimize the number of individuals needing vaccination to control an outbreak is a well-established area of study in mathematical epidemiology. However, for certain diseases, public policy tends to prioritize…

种群与进化 · 定量生物学 2026-01-30 J. Orestes Cerdeira , Fabio A. C. C. Chalub , Matheus Hansen
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