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Multimodal evidence is critical in computational pathology: gigapixel whole slide images capture tumor morphology, while patient-level clinical descriptors preserve complementary context for prognosis. Integrating such heterogeneous signals…

计算机视觉与模式识别 · 计算机科学 2026-02-05 Chengying She , Chengwei Chen , Xinran Zhang , Ben Wang , Lizhuang Liu , Chengwei Shao , Yun Bian

In a complex disease such as tuberculosis, the evidence for the disease and its evolution may be present in multiple modalities such as clinical, genomic, or imaging data. Effective patient-tailored outcome prediction and therapeutic…

Multimodal pathology-genomic analysis is critical for cancer survival prediction. However, existing approaches predominantly integrate formalin-fixed paraffin-embedded (FFPE) slides with genomic data, while neglecting the availability of…

计算机视觉与模式识别 · 计算机科学 2025-06-25 Mingcheng Qu , Guang Yang , Donglin Di , Yue Gao , Tonghua Su , Yang Song , Lei Fan

Multi-disease diagnosis using multi-modal data like electronic health records and medical imaging is a critical clinical task. Although existing deep learning methods have achieved initial success in this area, a significant gap persists…

多媒体 · 计算机科学 2025-09-22 Yueheng Jiang , Peng Zhang

The recent advancement of spatial transcriptomics (ST) allows to characterize spatial gene expression within tissue for discovery research. However, current ST platforms suffer from low resolution, hindering in-depth understanding of…

图像与视频处理 · 电气工程与系统科学 2025-11-05 Xiaofei Wang , Xingxu Huang , Stephen J. Price , Chao Li

Predicting the response of a patient to a cancer treatment is of high interest. Nonetheless, this task is still challenging from a medical point of view due to the complexity of the interaction between the patient organism and the…

计算机视觉与模式识别 · 计算机科学 2024-08-09 Bilel Guetarni , Feryal Windal , Halim Benhabiles , Mahfoud Chaibi , Romain Dubois , Emmanuelle Leteurtre , Dominique Collard

Accurate prediction of cardiovascular diseases remains imperative for early diagnosis and intervention, necessitating robust and precise predictive models. Recently, there has been a growing interest in multi-modal learning for uncovering…

计算机视觉与模式识别 · 计算机科学 2024-11-12 Francesco Girlanda , Olga Demler , Bjoern Menze , Neda Davoudi

Cancer survival prediction requires integrating pathological Whole Slide Images (WSIs) and genomic profiles, a challenging task due to the inherent heterogeneity and the complexity of modeling both inter- and intra-modality interactions.…

图像与视频处理 · 电气工程与系统科学 2025-07-08 Mingxin Liu , Chengfei Cai , Jun Li , Pengbo Xu , Jinze Li , Jiquan Ma , Jun Xu

Semi-supervised learning addresses the issue of limited annotations in medical images effectively, but its performance is often inadequate for complex backgrounds and challenging tasks. Multi-modal fusion methods can significantly improve…

计算机视觉与模式识别 · 计算机科学 2025-06-23 Dongdong Meng , Sheng Li , Hao Wu , Guoping Wang , Xueqing Yan

Multimodal medical imaging plays a pivotal role in clinical diagnosis and research, as it combines information from various imaging modalities to provide a more comprehensive understanding of the underlying pathology. Recently, deep…

Foundation models have emerged as a powerful paradigm in computational pathology (CPath), enabling scalable and generalizable analysis of histopathological images. While early developments centered on uni-modal models trained solely on…

计算机视觉与模式识别 · 计算机科学 2025-03-21 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Xiaohui Chen , Yi He , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Accurate diagnosis and treatment of complex diseases require integrating histological, molecular, and clinical data, yet in practice these modalities are often incomplete owing to tissue scarcity, assay cost, and workflow constraints.…

计算机视觉与模式识别 · 计算机科学 2026-04-07 Jinxi Xiang , Mingjie Li , Siyu Hou , Yijiang Chen , Xiangde Luo , Yuanfeng Ji , Xiang Zhou , Ehsan Adeli , Akshay Chaudhari , Curtis P. Langlotz , Kilian M. Pohl , Ruijiang Li

The elective clinical target volume (CTV-N) in oropharyngeal squamous cell carcinoma (OPSCC) is currently based mostly on the prevalence of lymph node metastases in different lymph node levels (LNLs) for a given primary tumor location. We…

The objective of this paper is to provide a baseline for performing multi-modal data classification on a novel open multimodal dataset of hepatocellular carcinoma (HCC), which includes both image data (contrast-enhanced CT and MRI images)…

Cancer survival prediction from whole slide images (WSIs) is a challenging task in computational pathology due to the large size, irregular shape, and high granularity of the WSIs. These characteristics make it difficult to capture the full…

图像与视频处理 · 电气工程与系统科学 2025-03-05 Rustin Soraki , Huayu Wang , Joann G. Elmore , Linda Shapiro

Cancer has relational information residing at varying scales, modalities, and resolutions of the acquired data, such as radiology, pathology, genomics, proteomics, and clinical records. Integrating diverse data types can improve the…

机器学习 · 计算机科学 2024-07-29 Asim Waqas , Aakash Tripathi , Ravi P. Ramachandran , Paul Stewart , Ghulam Rasool

Visual microscopic study of diseased tissue by pathologists has been the cornerstone for cancer diagnosis and prognostication for more than a century. Recently, deep learning methods have made significant advances in the analysis and…

图像与视频处理 · 电气工程与系统科学 2022-09-30 Puria Azadi Moghadam , Sanne Van Dalen , Karina C. Martin , Jochen Lennerz , Stephen Yip , Hossein Farahani , Ali Bashashati

Assessing the pre-operative risk of lymph node metastases in endometrial cancer patients is a complex and challenging task. In principle, machine learning and deep learning models are flexible and expressive enough to capture the dynamics…

Healthcare applications are inherently multimodal, benefiting greatly from the integration of diverse data sources. However, the modalities available in clinical settings can vary across different locations and patients. A key area that…

计算机视觉与模式识别 · 计算机科学 2025-09-04 Mohammed Amer , Mohamed A. Suliman , Tu Bui , Nuria Garcia , Serban Georgescu

Prognostic task is of great importance as it closely related to the survival analysis of patients, the optimization of treatment plans and the allocation of resources. The existing prognostic models have shown promising results on specific…

图像与视频处理 · 电气工程与系统科学 2025-01-14 Binyu Zhang , Shichao Li , Junpeng Jian , Zhu Meng , Limei Guo , Zhicheng Zhao