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Histomorphology is crucial in cancer diagnosis. However, existing whole slide image (WSI) classification methods struggle to effectively incorporate histomorphology information, limiting their ability to capture key pathological features.…

计算机视觉与模式识别 · 计算机科学 2025-12-01 Baizhi Wang , Rui Yan , Wenxin Ma , Xu Zhang , Yuhao Wang , Xiaolong Li , Yunjie Gu , Zihang Jiang , S. Kevin Zhou

In the field of semi-supervised medical image segmentation, the shortage of labeled data is the fundamental problem. How to effectively learn image features from unlabeled images to improve segmentation accuracy is the main research…

计算机视觉与模式识别 · 计算机科学 2023-10-11 Zhanhong Qiu , Haitao Gan , Ming Shi , Zhongwei Huang , Zhi Yang

Annotating cancerous regions in whole-slide images (WSIs) of pathology samples plays a critical role in clinical diagnosis, biomedical research, and machine learning algorithms development. However, generating exhaustive and accurate…

计算机视觉与模式识别 · 计算机科学 2022-06-09 Zhenzhen Wang , Carla Saoud , Sintawat Wangsiricharoen , Aaron W. James , Aleksander S. Popel , Jeremias Sulam

Partial label learning (PLL) aims to solve the problem where each training instance is associated with a set of candidate labels, one of which is the correct label. Most PLL algorithms try to disambiguate the candidate label set, by either…

机器学习 · 计算机科学 2018-05-09 Gengyu Lyu , Songhe Feng , Congyang Lang

Partial label learning (PLL) seeks to train generalizable classifiers from datasets with inexact supervision, a common challenge in real-world applications. Existing studies have developed numerous approaches to progressively refine and…

机器学习 · 计算机科学 2025-06-06 Kuang He , Wei Tang , Tong Wei , Min-Ling Zhang

Acquiring annotations for whole slide images (WSIs)-based deep learning tasks, such as creating tissue segmentation masks or detecting mitotic figures, is a laborious process due to the extensive image size and the significant manual work…

计算机视觉与模式识别 · 计算机科学 2024-07-10 Jingna Qiu , Marc Aubreville , Frauke Wilm , Mathias Öttl , Jonas Utz , Maja Schlereth , Katharina Breininger

Partial label learning (PLL) is a typical weakly supervised learning problem, where each training example is associated with a set of candidate labels among which only one is true. Most existing PLL approaches assume that the incorrect…

机器学习 · 计算机科学 2021-10-27 Ning Xu , Congyu Qiao , Xin Geng , Min-Ling Zhang

We propose an end-to-end deep learning method that learns to estimate emphysema extent from proportions of the diseased tissue. These proportions were visually estimated by experts using a standard grading system, in which grades correspond…

计算机视觉与模式识别 · 计算机科学 2018-07-24 Gerda Bortsova , Florian Dubost , Silas Ørting , Ioannis Katramados , Laurens Hogeweg , Laura Thomsen , Mathilde Wille , Marleen de Bruijne

Oncologists often rely on a multitude of data, including whole-slide images (WSIs), to guide therapeutic decisions, aiming for the best patient outcome. However, predicting the prognosis of cancer patients can be a challenging task due to…

图像与视频处理 · 电气工程与系统科学 2025-04-01 M Rita Verdelho , Alexandre Bernardino , Catarina Barata

Weakly supervised segmentation requires assigning a label to every pixel based on training instances with partial annotations such as image-level tags, object bounding boxes, labeled points and scribbles. This task is challenging, as coarse…

计算机视觉与模式识别 · 计算机科学 2021-05-12 Tsung-Wei Ke , Jyh-Jing Hwang , Stella X. Yu

Consecutive thin sections of tissue samples make it possible to study local variation in e.g. protein expression and tumor heterogeneity by staining for a new protein in each section. In order to compare and correlate patterns of different…

计算机视觉与模式识别 · 计算机科学 2019-01-25 Leslie Solorzano , Gabriela M. Almeida , Bárbara Mesquita , Diana Martins , Carla Oliveira , Carolina Wählby

Accurate diagnosis of disease often depends on the exhaustive examination of Whole Slide Images (WSI) at microscopic resolution. Efficient handling of these data-intensive images requires lossy compression techniques. This paper…

Presenting whole slide images (WSIs) as graph will enable a more efficient and accurate learning framework for cancer diagnosis. Due to the fact that a single WSI consists of billions of pixels and there is a lack of vast annotated datasets…

图像与视频处理 · 电气工程与系统科学 2023-06-09 Milan Aryal , Nasim Yahyasoltani

Whole-slide image (WSI) classification in computational pathology is commonly formulated as slide-level Multiple Instance Learning (MIL) with a single global bag representation. However, slide-level MIL is fundamentally underconstrained:…

Breast cancer is the most prevalent cancer in women worldwide. Histopathology image analysis serves as the gold standard for cancer diagnosis. In this regard, whole-slide imaging (WSI), a revolutionary technology in digital pathology,…

统计方法学 · 统计学 2026-04-21 Baichen Yu , Xuetong Li , Jing Zhou , Hansheng Wang

High-resolution microscopy images of tissue specimens provide detailed information about the morphology of normal and diseased tissue. Image analysis of tissue morphology can help cancer researchers develop a better understanding of cancer…

In this paper, we present a deep learning segmentation approach to classify and quantify the two most prevalent primary liver cancers - hepatocellular carcinoma and intrahepatic cholangiocarcinoma - from hematoxylin and eosin (H&E) stained…

Whole slide images~(WSIs) are digitized images of tissues placed in glass slides using advanced scanners. The digital processing of WSIs is challenging as they are gigapixel images and stored in multi-resolution format. A common challenge…

图像与视频处理 · 电气工程与系统科学 2023-10-30 Saba Heidari Gheshlaghi , Milan Aryal , Nasim Yahyasoltani , Masoud Ganji

Anomaly detection for Magnetic Resonance Images (MRIs) can be solved with unsupervised methods by learning the distribution of healthy images and identifying anomalies as outliers. In presence of an additional dataset of unlabelled data…

机器学习 · 计算机科学 2020-07-27 Alexandra-Ioana Albu , Alina Enescu , Luigi Malagò

We consider machine-learning-based thyroid-malignancy prediction from cytopathology whole-slide images (WSI). Multiple instance learning (MIL) approaches, typically used for the analysis of WSIs, divide the image (bag) into patches…