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Neural networks trained on real-world datasets with long-tailed label distributions are biased towards frequent classes and perform poorly on infrequent classes. The imbalance in the ratio of positive and negative samples for each class…

计算机视觉与模式识别 · 计算机科学 2021-05-25 Kevin Duarte , Yogesh S. Rawat , Mubarak Shah

Pathology computing has dramatically improved pathologists' workflow and diagnostic decision-making processes. Although computer-aided diagnostic systems have shown considerable value in whole slide image (WSI) analysis, the problem of…

计算机视觉与模式识别 · 计算机科学 2024-11-19 Yonghuang Wu , Xuan Xie , Xinyuan Niu , Chengqian Zhao , Jinhua Yu

Whole slide image (WSI) classification requires repetitive zoom-in and out for pathologists, as only small portions of the slide may be relevant to detecting cancer. Due to the lack of patch-level labels, multiple instance learning (MIL) is…

计算机视觉与模式识别 · 计算机科学 2023-11-30 Seongho Keum , Sanghyun Kim , Soojeong Lee , Juho Lee

Bag-based Multiple Instance Learning (MIL) approaches have emerged as the mainstream methodology for Whole Slide Image (WSI) classification. However, most existing methods adopt a segmented training strategy, which first extracts features…

计算机视觉与模式识别 · 计算机科学 2025-03-13 Jiangping Wen , Jinyu Wen , Meie Fang

Due to the difficulties of obtaining multimodal paired images in clinical practice, recent studies propose to train brain tumor segmentation models with unpaired images and capture complementary information through modality translation.…

计算机视觉与模式识别 · 计算机科学 2022-08-29 Zecheng Liu , Jia Wei , Rui Li

Whole Slide Image (WSI) analysis is a powerful method to facilitate the diagnosis of cancer in tissue samples. Automating this diagnosis poses various issues, most notably caused by the immense image resolution and limited annotations. WSIs…

计算机视觉与模式识别 · 计算机科学 2023-04-19 Ahmet Gokberk Gul , Oezdemir Cetin , Christoph Reich , Tim Prangemeier , Nadine Flinner , Heinz Koeppl

In many applications, especially due to lack of supervision or privacy concerns, the training data is grouped into bags of instances (feature-vectors) and for each bag we have only an aggregate label derived from the instance-labels in the…

机器学习 · 计算机科学 2025-07-16 Sagalpreet Singh , Navodita Sharma , Shreyas Havaldar , Rishi Saket , Aravindan Raghuveer

Recent breakthroughs in object detection and image classification using Convolutional Neural Networks (CNNs) are revolutionizing the state of the art in medical imaging, and microscopy in particular presents abundant opportunities for…

图像与视频处理 · 电气工程与系统科学 2020-07-07 Rui Aguiar , Jon Braatz

Whole Slide Images (WSI), obtained by high-resolution digital scanning of microscope slides at multiple scales, are the cornerstone of modern Digital Pathology. However, they represent a particular challenge to AI-based/AI-mediated analysis…

计算机视觉与模式识别 · 计算机科学 2024-04-12 Martim Afonso , Praphulla M. S. Bhawsar , Monjoy Saha , Jonas S. Almeida , Arlindo L. Oliveira

Segmentation of tumors in brain MRI images is a challenging task, where most recent methods demand large volumes of data with pixel-level annotations, which are generally costly to obtain. In contrast, image-level annotations, where only…

图像与视频处理 · 电气工程与系统科学 2019-11-07 Sergey Pavlov , Alexey Artemov , Maksim Sharaev , Alexander Bernstein , Evgeny Burnaev

Partially-supervised learning can be challenging for segmentation due to the lack of supervision for unlabeled structures, and the methods directly applying fully-supervised learning could lead to incompatibility, meaning ground truth is…

计算机视觉与模式识别 · 计算机科学 2022-06-22 Ke Zhang , Xiahai Zhuang

Specific and effective breast cancer therapy relies on the accurate quantification of PD-L1 positivity in tumors, which appears in the form of brown stainings in high resolution whole slide images (WSIs). However, the retrieval and…

Partial-label learning (PLL) is a typical weakly supervised learning problem, where each training instance is equipped with a set of candidate labels among which only one is the true label. Most existing methods elaborately designed…

机器学习 · 计算机科学 2020-09-08 Jiaqi Lv , Miao Xu , Lei Feng , Gang Niu , Xin Geng , Masashi Sugiyama

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

定量方法 · 定量生物学 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

The diagnosis and segmentation of tumors using any medical diagnostic tool can be challenging due to the varying nature of this pathology. Magnetic Reso- nance Imaging (MRI) is an established diagnostic tool for various diseases and…

计算机视觉与模式识别 · 计算机科学 2017-11-01 Tanvi Gupta , Pranay Manocha , Tapan K. Gandhi , RK Gupta , BK Panigrahi

Recently, various deep learning methods have shown significant successes in medical image analysis, especially in the detection of cancer metastases in hematoxylin and eosin (H&E) stained whole-slide images (WSIs). However, in order to…

图像与视频处理 · 电气工程与系统科学 2023-03-21 Yinsheng He , Xingyu Li

Nuclei segmentation is a fundamental task in histopathology image analysis. Typically, such segmentation tasks require significant effort to manually generate accurate pixel-wise annotations for fully supervised training. To alleviate such…

计算机视觉与模式识别 · 计算机科学 2020-07-13 Hui Qu , Pengxiang Wu , Qiaoying Huang , Jingru Yi , Zhennan Yan , Kang Li , Gregory M. Riedlinger , Subhajyoti De , Shaoting Zhang , Dimitris N. Metaxas

We propose a method to accurately obtain the ratio of tumor cells over an entire histological slide. We use deep fully convolutional neural network models trained to detect and classify cells on images of H&E-stained tissue sections.…

图像与视频处理 · 电气工程与系统科学 2021-01-29 Eric Cosatto , Kyle Gerard , Hans-Peter Graf , Maki Ogura , Tomoharu Kiyuna , Kanako C. Hatanaka , Yoshihiro Matsuno , Yutaka Hatanaka

Multiple Instance learning (MIL) models have been extensively used in pathology to predict biomarkers and risk-stratify patients from gigapixel-sized images. Machine learning problems in medical imaging often deal with rare diseases, making…

计算机视觉与模式识别 · 计算机科学 2023-09-12 Dinkar Juyal , Siddhant Shingi , Syed Ashar Javed , Harshith Padigela , Chintan Shah , Anand Sampat , Archit Khosla , John Abel , Amaro Taylor-Weiner

This work addresses the challenge of training supervised machine or deep learning models on orbiting platforms where we are generally constrained by limited on-board hardware capabilities and restricted uplink bandwidths to upload. We aim…

计算机视觉与模式识别 · 计算机科学 2023-12-12 Raúl Ramos-Pollán , Fabio A. González