相关论文: Frailty Assessment in Aortic Stenosis based on Dyn…

Frailty is a geriatric syndrome associated with the lack of physiological reserve and consequent adverse outcomes (therapy complications and death) in older adults. Recent research has shown associations between heart rate (HR) dynamics (HR…

This study presents an application of machine learning (ML) methods for detecting the presence of stenoses and aneurysms in the human arterial system. Four major forms of arterial disease -- carotid artery stenosis (CAS), subclavian artery…

Aortic stenosis (AS) is a degenerative valve condition that causes substantial morbidity and mortality. This condition is under-diagnosed and under-treated. In clinical practice, AS is diagnosed with expert review of transthoracic…

Background: Frailty, a state of increased vulnerability to adverse health outcomes, has garnered significant attention in research and clinical practice. Existing constructs aggregate clinical features or health deficits into a single…

The growing global elderly population is expected to increase the prevalence of frailty, posing significant challenges to healthcare systems. Frailty, a syndrome associated with ageing, is characterised by progressive health decline,…

Atrial fibrillation (AF) is a common cardiac arrhythmia characterized by rapid and irregular contractions of the atria. It significantly elevates the risk of strokes due to slowed blood flow in the atria, especially in the left atrial…

Frailty and functional decline strongly influence treatment tolerance and outcomes in older patients with cancer, yet assessment is typically limited to infrequent clinic visits. We propose a multimodal wearable framework to estimate…

Aortic valve stenosis (AVS) presents challenges in asymptomatic detection, resulting in delayed intervention. This study aims to understand how AVS affects pulse wave (PW) morphology. A PW database of 16,038 virtual subjects aged 50 to 75…

Falls during walking are a major health issue in the elderly population. Older individuals are usually more cautious, work more slowly, take shorter steps, and exhibit increased step-to-step variability. They often have impaired dynamic…

To better understand mortality change with age capturing the variability in individuals' rates of aging, we performed comprehensive analysis of statistical properties of a cumulative index of age-associated disorders (deficits), called a…

Aims: The presence of coronary tandem lesions poses a significant challenge for the accurate diagnosis and management of coronary artery diseases. This study set out to provide a deeper understanding of the haemodynamic interactions between…

Aortic stenosis (AS) is a life-threatening condition caused by a narrowing of the aortic valve, leading to impaired blood flow. Despite its high prevalence, access to echocardiography (echo), the gold-standard diagnostic tool, is often…

Identifying frail older adults in an ageing population is essential for improving healthcare services. This study proposes a composite indicator to assess individual frailty levels using administrative healthcare data. Given the complex and…

Aortic aneurysm disease ranks consistently in the top 20 causes of death in the U.S. population. Thoracic aortic aneurysm is manifested as an abnormal bulging of thoracic aortic wall and it is a leading cause of death in adults. From the…

Frailty is a common and critical condition in elderly adults, which may lead to further deterioration of health. However, difficulties and complexities exist in traditional frailty assessments based on activity-related questionnaires. These…

Background: The relative contribution of different aging-associated processes to the age phenotype may differ among individuals, creating variability in aging manifestations among age-peers. Capturing this variability can significantly…

Abdominal aortic aneurysm (AAA) is a permanent and irreversible dilation of the lower region of the aorta. It is typically an asymptomatic condition that if left untreated can expand to the point of rupture. Mechanically-speaking, rupture…

Frailty assessment is crucial for stratifying populations and addressing healthcare challenges associated with ageing. This study proposes a Frailty Index based on administrative health data, with the aim of facilitating informed…

Abdominal aortic aneurysm (AAA) is a life-threatening condition characterized by the progressive dilation of the aorta, which can lead to rupture if undetected or untreated. Stress-based rupture risk estimation using computational…

Physical activity during hip fracture rehabilitation is essential for mitigating long-term functional decline in geriatric patients. However, it is rarely quantified in clinical practice. Existing continuous monitoring systems with…