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The focus of this work is on spatial variable selection for scalar-on-image regression. We propose a new class of Bayesian nonparametric models, soft-thresholded Gaussian processes and develop the efficient posterior computation algorithms.…

统计方法学 · 统计学 2016-04-13 Jian Kang , Brian J. Reich , Ana-Maria Staicu

Bayesian Image-on-Scalar Regression (ISR) provides flexible, uncertainty-aware neuroimaging analysis. However, applying ISR to large-scale datasets such as the UK Biobank is challenging due to intensive computational demands and the need to…

应用统计 · 统计学 2026-02-09 Yuliang Xu , Timothy D. Johnson , Thomas E. Nichols , Jian Kang

A central question in multimodal neuroimaging analysis is to understand the association between two imaging modalities and to identify brain regions where such an association is statistically significant. In this article, we propose a…

统计方法学 · 统计学 2024-11-28 Moyan Li , Lexin Li , Jian Kang

Motivated by the needs of selecting important features for massive neuroimaging data, we propose a spatially varying coefficient model (SVCMs) with sparsity and piecewise smoothness imposed on the coefficient functions. A new class of…

统计方法学 · 统计学 2015-05-01 Ran Shi , Jian Kang

In this article, we propose a novel spatial global-local spike-and-slab selection prior for image-on-scalar regression. We consider a Bayesian hierarchical Gaussian process model for image smoothing, that uses a flexible Inverse-Wishart…

统计方法学 · 统计学 2022-12-19 Zijian Zeng , Meng Li , Marina Vannucci

Most brain disorders are very heterogeneous in terms of their underlying biology and developing analysis methods to model such heterogeneity is a major challenge. A promising approach is to use probabilistic regression methods to estimate…

机器学习 · 统计学 2018-12-03 Seyed Mostafa Kia , Christian F. Beckmann , Andre F. Marquand

In regression-based analyses of group-level neuroimage data researchers typically fit a series of marginal general linear models to image outcomes at each spatially-referenced pixel. Spatial regularization of effects of interest is usually…

统计方法学 · 统计学 2024-09-26 Andrew S. Whiteman , Timothy D. Johnson , Jian Kang

In neuroimaging studies, it becomes increasingly important to study associations between different imaging modalities using image-on-image regression (IIR), which faces challenges in interpretation, statistical inference, and prediction.…

应用统计 · 统计学 2026-03-24 Guoxuan Ma , Bangyao Zhao , Hasan Abu-Amara , Jian Kang

Motivated by recent data analyses in biomedical imaging studies, we consider a class of image-on-scalar regression models for imaging responses and scalar predictors. We propose using flexible multivariate splines over triangulations to…

统计方法学 · 统计学 2021-06-04 Shan Yu , Guannan Wang , Li Wang , Lijian Yang

We develop a fully Bayesian framework for function-on-scalars regression with many predictors. The functional data response is modeled nonparametrically using unknown basis functions, which produces a flexible and data-adaptive functional…

统计方法学 · 统计学 2018-10-25 Daniel R. Kowal , Daniel C. Bourgeois

Bayesian methods for learning Gaussian graphical models offer a principled framework for quantifying model uncertainty and incorporating prior knowledge. However, their scalability is constrained by the computational cost of jointly…

统计方法学 · 统计学 2025-08-28 Reza Mohammadi , Marit Schoonhoven , Lucas Vogels , S. Ilker Birbil

Multi-subject functional magnetic resonance imaging (fMRI) data has been increasingly used to study the population-wide relationship between human brain activity and individual biological or behavioral traits. A common method is to regress…

应用统计 · 统计学 2015-09-15 Fan Li , Tingting Zhang , Quanli Wang , Marlen Z. Gonzalez , Erin L. Maresh , James A. Coan

Image-on-scalar regression has been a popular approach to modeling the association between brain activities and scalar characteristics in neuroimaging research. The associations could be heterogeneous across individuals in the population,…

统计方法学 · 统计学 2023-07-04 Zikai Lin , Yajuan Si , Jian Kang

In this paper, we develop a novel spatial variable selection method for scalar on vector-valued image regression in a multi-group setting. Here, 'vector-valued image' refers to the imaging datasets that contain vector-valued information at…

统计方法学 · 统计学 2024-10-22 Arkaprava Roy , Zhou Lan

Scalar-on-image regression aims to investigate changes in a scalar response of interest based on high-dimensional imaging data. We propose a novel Bayesian nonparametric scalar-on-image regression model that utilises the spatial coordinates…

统计方法学 · 统计学 2022-06-23 Mica Teo Shu Xian , Sara Wade

Analysis of brain imaging scans is critical to understanding the way the human brain functions, which can be leveraged to treat injuries and conditions that affect the quality of life for a significant portion of the human population. In…

统计方法学 · 统计学 2022-03-02 Daniel Spencer , David Bolin , Mary Beth Nebel , Amanda Mejia

This paper presents a Bayesian regression model relating scalar outcomes to brain functional connectivity represented as symmetric positive definite (SPD) matrices. Unlike many proposals that simply vectorize the matrix-valued connectivity…

统计方法学 · 统计学 2024-03-28 Xiaomeng Ju , Hyung G. Park , Thaddeus Tarpey

We propose a novel tensor-on-tensor modeling framework that flexibly models nonlinear voxel-level relationships using Gaussian process (GP) priors, while incorporating the spatial structure of the output tensor through low-rank tensor-based…

统计方法学 · 统计学 2026-04-10 Yajie Liu , Hengrui Luo , Suprateek Kundu

Multi-task regression attempts to exploit the task similarity in order to achieve knowledge transfer across related tasks for performance improvement. The application of Gaussian process (GP) in this scenario yields the non-parametric yet…

机器学习 · 统计学 2021-09-21 Haitao Liu , Jiaqi Ding , Xinyu Xie , Xiaomo Jiang , Yusong Zhao , Xiaofang Wang

Recent medical imaging studies have given rise to distinct but inter-related datasets corresponding to multiple experimental tasks or longitudinal visits. Standard scalar-on-image regression models that fit each dataset separately are not…

统计方法学 · 统计学 2022-01-21 Xin Ma , Suprateek Kundu
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