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Accurate prediction of the likelihood of recurrence is important in the selection of postoperative treatment for patients with early-stage breast cancer. In this study, we investigated whether deep learning algorithms can predict patients'…

图像与视频处理 · 电气工程与系统科学 2025-12-22 Geongyu Lee , Joonho Lee , Tae-Yeong Kwak , Sun Woo Kim , Youngmee Kwon , Chungyeul Kim , Hyeyoon Chang

Classification of histologic patterns in lung adenocarcinoma is critical for determining tumor grade and treatment for patients. However, this task is often challenging due to the heterogeneous nature of lung adenocarcinoma and the…

计算机视觉与模式识别 · 计算机科学 2019-02-01 Jason W. Wei , Laura J. Tafe , Yevgeniy A. Linnik , Louis J. Vaickus , Naofumi Tomita , Saeed Hassanpour

Aim: Early detection and correct diagnosis of lung cancer are the most important steps in improving patient outcome. This study aims to assess which deep learning models perform best in lung cancer diagnosis. Methods: Non-small cell lung…

计算机视觉与模式识别 · 计算机科学 2018-03-16 Zhang Li , Zheyu Hu , Jiaolong Xu , Tao Tan , Hui Chen , Zhi Duan , Ping Liu , Jun Tang , Guoping Cai , Quchang Ouyang , Yuling Tang , Geert Litjens , Qiang Li

With the rise and ever-increasing potential of deep learning techniques in recent years, publicly available medical datasets became a key factor to enable reproducible development of diagnostic algorithms in the medical domain. Medical data…

计算机视觉与模式识别 · 计算机科学 2022-09-05 Kai Packhäuser , Sebastian Gündel , Nicolas Münster , Christopher Syben , Vincent Christlein , Andreas Maier

Recently, various deep learning methods have shown significant successes in medical image analysis, especially in the detection of cancer metastases in hematoxylin and eosin (H&E) stained whole-slide images (WSIs). However, in order to…

图像与视频处理 · 电气工程与系统科学 2023-03-21 Yinsheng He , Xingyu Li

Medical imaging is an essential tool in many areas of medical applications, used for both diagnosis and treatment. However, reading medical images and making diagnosis or treatment recommendations require specially trained medical…

计算机视觉与模式识别 · 计算机科学 2019-03-13 Wentao Zhu

Lung squamous cell carcinoma (LSCC) has a high recurrence and metastasis rate. Factors influencing recurrence and metastasis are currently unknown and there are no distinct histopathological or morphological features indicating the risks of…

计算机视觉与模式识别 · 计算机科学 2023-02-09 Weicheng Zhu , Carlos Fernandez-Granda , Narges Razavian

For several cancer patients, operative resection with curative intent can end up in early recurrence of the cancer. Current limitations in peri-operative cancer staging and especially intra-operative misidentification of visible metastases…

图像与视频处理 · 电气工程与系统科学 2023-06-21 Thomas Schnelldorfer , Janil Castro , Atoussa Goldar-Najafi , Liping Liu

Histopathological images are widely used for the analysis of diseased (tumor) tissues and patient treatment selection. While the majority of microscopy image processing was previously done manually by pathologists, recent advances in…

图像与视频处理 · 电气工程与系统科学 2024-07-12 Andrey Ignatov , Josephine Yates , Valentina Boeva

Deep learning assisted digital pathology has the potential to impact clinical practice in significant ways. In recent studies, deep neural network (DNN) enabled analysis outperforms human pathologists. Increasing sizes and complexity of the…

图像与视频处理 · 电气工程与系统科学 2024-06-04 Haowen Zhou , Steven , Lin , Mark Watson , Cory T. Bernadt , Oumeng Zhang , Ramaswamy Govindan , Richard J. Cote , Changhuei Yang

For diagnosing melanoma, hematoxylin and eosin (H&E) stained tissue slides remains the gold standard. These images contain quantitative information in different magnifications. In the present study, we investigated whether deep…

组织与器官 · 定量生物学 2019-04-15 Peizhen Xie , Ke Zuo , Yu Zhang , Fangfang Li , Mingzhu Yin , Kai Lu

Automated region of interest detection in histopathological image analysis is a challenging and important topic with tremendous potential impact on clinical practice. The deep-learning methods used in computational pathology may help us to…

图像与视频处理 · 电气工程与系统科学 2024-05-17 Yi Cui , Yao Li , Jayson R. Miedema , Sharon N. Edmiston , Sherif Farag , J. S. Marron , Nancy E. Thomas

Objectives: to propose a fully-automatic computer-aided diagnosis (CAD) solution for liver lesion characterization, with uncertainty estimation. Methods: we enrolled 400 patients who had either liver resection or a biopsy and was diagnosed…

图像与视频处理 · 电气工程与系统科学 2021-10-19 Peng Wang , Yuhsuan Wu , Bolin Lai , Xiao-Yun Zhou , Le Lu , Wendi Liu , Huabang Zhou , Lingyun Huang , Jing Xiao , Adam P. Harrison , Ningyang Jia , Heping Hu

Histopathology images; microscopy images of stained tissue biopsies contain fundamental prognostic information that forms the foundation of pathological analysis and diagnostic medicine. However, diagnostics from histopathology images…

计算机视觉与模式识别 · 计算机科学 2019-10-30 Aïcha BenTaieb , Ghassan Hamarneh

We developed a deep learning framework that helps to automatically identify and segment lung cancer areas in patients' tissue specimens. The study was based on a cohort of lung cancer patients operated at the Uppsala University Hospital.…

计算机视觉与模式识别 · 计算机科学 2018-07-30 Nikolay Burlutskiy , Feng Gu , Lena Kajland Wilen , Max Backman , Patrick Micke

The International Symposium on Biomedical Imaging (ISBI) held a grand challenge to evaluate computational systems for the automated detection of metastatic breast cancer in whole slide images of sentinel lymph node biopsies. Our team won…

定量方法 · 定量生物学 2016-06-21 Dayong Wang , Aditya Khosla , Rishab Gargeya , Humayun Irshad , Andrew H. Beck

Accurate prediction of recurrence in clear cell renal cell carcinoma (ccRCC) remains a major clinical challenge due to the disease complex molecular, pathological, and clinical heterogeneity. Traditional prognostic models, which rely on…

图像与视频处理 · 电气工程与系统科学 2025-07-11 Hasaan Maqsood , Saif Ur Rehman Khan

Lung cancer, a malignancy originating in lung tissues, is commonly diagnosed and classified using medical imaging techniques, particularly computed tomography (CT). Despite the integration of machine learning and deep learning methods, the…

图像与视频处理 · 电气工程与系统科学 2025-10-21 Olajumoke O. Adekunle , Joseph D. Akinyemi , Khadijat T. Ladoja , Olufade F. W. Onifade

Cancer of unknown primary (CUP) is an enigmatic group of diagnoses where the primary anatomical site of tumor origin cannot be determined. This poses a significant challenge since modern therapeutics such as chemotherapy regimen and immune…

组织与器官 · 定量生物学 2021-07-14 Ming Y. Lu , Melissa Zhao , Maha Shady , Jana Lipkova , Tiffany Y. Chen , Drew F. K. Williamson , Faisal Mahmood

Melanoma diagnosed and treated in its early stages can increase the survival rate. A projected increase in skin cancer incidents and a dearth of dermatopathologists have emphasized the need for computational pathology (CPATH) systems. CPATH…

图像与视频处理 · 电气工程与系统科学 2023-11-07 Neel Kanwal , Roger Amundsen , Helga Hardardottir , Luca Tomasetti , Erling Sandoy Undersrud , Emiel A. M. Janssen , Kjersti Engan
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