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The integration of multi-modal Magnetic Resonance Imaging (MRI) and clinical data holds great promise for enhancing the diagnosis of neurological disorders (NDs) in real-world clinical settings. Deep Learning (DL) has recently emerged as a…

Diffusion Probabilistic Methods are employed for state-of-the-art image generation. In this work, we present a method for extending such models for performing image segmentation. The method learns end-to-end, without relying on a…

To achieve the highest perceptual quality, state-of-the-art diffusion models are optimized with objectives that typically look very different from the maximum likelihood and the Evidence Lower Bound (ELBO) objectives. In this work, we…

Open Set Domain Adaptation (OSDA) aims to cope with the distribution and label shifts between the source and target domains simultaneously, performing accurate classification for known classes while identifying unknown class samples in the…

Deep Learning systems have achieved great success in the past few years, even surpassing human intelligence in several cases. As of late, they have also established themselves in the biomedical and healthcare domains, where they have shown…

A major challenge in the segmentation of medical images is the large inter- and intra-observer variability in annotations provided by multiple experts. To address this challenge, we propose a novel method for multi-expert prediction using…

Deploying deep learning (DL) models in medical applications relies on predictive performance and other critical factors, such as conveying trustworthy predictive uncertainty. Uncertainty estimation (UE) methods provide potential solutions…

The recent achievements of Deep Learning rely on the test data being similar in distribution to the training data. In an ideal case, Deep Learning models would achieve Out-of-Distribution (OoD) Generalization, i.e. reliably make predictions…

This work introduces Variational Diffusion Distillation (VDD), a novel method that distills denoising diffusion policies into Mixtures of Experts (MoE) through variational inference. Diffusion Models are the current state-of-the-art in…

Diffusion-based data augmentation (DiffDA) has emerged as a promising approach to improving classification performance under data scarcity. However, existing works vary significantly in task configurations, model choices, and experimental…

This review explores anomaly localization in medical images using denoising diffusion models. After providing a brief methodological background of these models, including their application to image reconstruction and their conditioning…

Multi-channel EEG signals are commonly used for the diagnosis and assessment of diseases such as epilepsy. Currently, various EEG diagnostic algorithms based on deep learning have been developed. However, most research efforts focus solely…

With the successful adoption of machine learning on electronic health records (EHRs), numerous computational models have been deployed to address a variety of clinical problems. However, due to the heterogeneity of EHRs, models trained on…

The past few years have witnessed the great success of Diffusion models~(DMs) in generating high-fidelity samples in generative modeling tasks. A major limitation of the DM is its notoriously slow sampling procedure which normally requires…

Predicting potential outcomes of interventions from observational data is crucial for decision-making in medicine, but the task is challenging due to the fundamental problem of causal inference. Existing methods are largely limited to point…

Neuron segmentation in electron microscopy (EM) aims to reconstruct the complete neuronal connectome; however, current deep learning-based methods are limited by their reliance on large-scale training data and extensive, time-consuming…

Digital pathology has advanced significantly over the last decade, with Whole Slide Images (WSIs) encompassing vast amounts of data essential for accurate disease diagnosis. High-resolution WSIs are essential for precise diagnosis but…

Image aesthetic enhancement aims to perceive aesthetic deficiencies in images and perform corresponding editing operations, which is highly challenging and requires the model to possess creativity and aesthetic perception capabilities.…

Deformable image registration aims to precisely align medical images from different modalities or times. Traditional deep learning methods, while effective, often lack interpretability, real-time observability and adjustment capacity during…

Fairness is an important topic for medical image analysis, driven by the challenge of unbalanced training data among diverse target groups and the societal demand for equitable medical quality. In response to this issue, our research adopts…