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High-content phenotypic screening, including high-content imaging (HCI), has gained popularity in the last few years for its ability to characterize novel therapeutics without prior knowledge of the protein target. When combined with deep…

Robust visual recognition in underwater environments remains a significant challenge due to complex distortions such as turbidity, low illumination, and occlusion, which severely degrade the performance of standard vision systems. This…

计算机视觉与模式识别 · 计算机科学 2026-04-01 Taufikur Rahman Fuad , Sabbir Ahmed , Shahriar Ivan

In many scenarios of binary classification, only positive instances are provided in the training data, leaving the rest of the data unlabeled. This setup, known as positive-unlabeled (PU) learning, is addressed here with a network…

机器学习 · 计算机科学 2025-11-04 Dorit Hochbaum , Torpong Nitayanont

This paper introduces the Diabetic Foot Ulcers dataset (DFUC2021) for analysis of pathology, focusing on infection and ischaemia. We describe the data preparation of DFUC2021 for ground truth annotation, data curation and data analysis. The…

计算机视觉与模式识别 · 计算机科学 2021-08-16 Moi Hoon Yap , Bill Cassidy , Joseph M. Pappachan , Claire O'Shea , David Gillespie , Neil Reeves

We consider the use of the Joint Clustering and Matching (JCM) procedure for the supervised classification of a flow cytometric sample with respect to a number of predefined classes of such samples. The JCM procedure has been proposed as a…

定量方法 · 定量生物学 2014-11-12 Sharon X. Lee , Geoffrey J. McLachlan , Saumyadipta Pyne

Timely diagnosis of Intracranial hemorrhage (ICH) on Computed Tomography (CT) scans remains a clinical priority, yet the development of robust Artificial Intelligence (AI) solutions is still hindered by fragmented public data. To close this…

Mass spectrometry (MS) stands as a cornerstone analytical technique for molecular identification, yet de novo structure elucidation from spectra remains challenging due to the combinatorial complexity of chemical space and the inherent…

机器学习 · 计算机科学 2026-03-20 Jianan Nie , Peng Gao

Deep learning has revolutionized medical and biological imaging, particularly in segmentation tasks. However, segmenting biological cells remains challenging due to the high variability and complexity of cell shapes. Addressing this…

计算机视觉与模式识别 · 计算机科学 2025-06-03 Tianhao Zhang , Heather J. McCourty , Berardo M. Sanchez-Tafolla , Anton Nikolaev , Lyudmila S. Mihaylova

Single-cell genomics has significantly advanced our understanding of cellular behavior, catalyzing innovations in treatments and precision medicine. However, single-cell sequencing technologies are inherently destructive and can only…

机器学习 · 统计学 2024-11-08 Dominik Klein , Théo Uscidda , Fabian Theis , Marco Cuturi

Data obtained from Flow Cytometry present pronounced variability due to biological and technical reasons. Biological variability is a well-known phenomenon produced by measurements on different individuals, with different characteristics…

Computer-aided methods for analyzing white blood cells (WBC) have become widely popular due to the complexity of the manual process. Recent works have shown highly accurate segmentation and detection of white blood cells from microscopic…

图像与视频处理 · 电气工程与系统科学 2019-10-03 Changhun Jung , Mohammed Abuhamad , Jumabek Alikhanov , Aziz Mohaisen , Kyungja Han , DaeHun Nyang

Acute lymphoblastic leukaemia (ALL) is a blood malignancy that mainly affects adults and children. This study looks into the use of deep learning, specifically Convolutional Neural Networks (CNNs), for the detection and classification of…

图像与视频处理 · 电气工程与系统科学 2024-09-11 Sabit Ahamed Preanto , Md. Taimur Ahad , Yousuf Rayhan Emon , Sumaya Mustofa , Md Alamin

The color of skin lesions is an important diagnostic feature for identifying malignant melanoma and other skin diseases. Typical colors associated with melanocytic lesions include tan, brown, black, red, white, and blue gray. This study…

定量方法 · 定量生物学 2026-01-30 M. A. Rasel , Sameem Abdul Kareem , Unaizah Obaidellah

White blood cells (WBCs) play a crucial role in safeguarding the human body against pathogens and foreign substances. Leveraging the abundance of WBC imaging data and the power of deep learning algorithms, automated WBC analysis has the…

图像与视频处理 · 电气工程与系统科学 2023-10-23 Aditya Shankar Pal , Debojyoti Biswas , Joy Mahapatra , Debasis Banerjee , Prantar Chakrabarti , Utpal Garain

Much data with graph structures satisfy the principle of homophily, meaning that connected nodes tend to be similar with respect to a specific attribute. As such, ubiquitous datasets for graph machine learning tasks have generally been…

机器学习 · 计算机科学 2021-07-07 Derek Lim , Xiuyu Li , Felix Hohne , Ser-Nam Lim

Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) derived from somatic cells (SCs) provide promising resources for regenerative medicine and medical research, leading to a daily identification of new cell lines.…

定量方法 · 定量生物学 2013-02-15 Anyou Wang

In recent years, deep learning has vastly improved the identification and diagnosis of various diseases in plants. In this report, we investigate the problem of pathology classification using images of a single leaf. We explore the use of…

计算机视觉与模式识别 · 计算机科学 2020-12-02 Sedrick Scott Keh

We present Glioma C6, a new open dataset for instance segmentation of glioma C6 cells, designed as both a benchmark and a training resource for deep learning models. The dataset comprises 75 high-resolution phase-contrast microscopy images…

计算机视觉与模式识别 · 计算机科学 2025-11-11 Roman Malashin , Svetlana Pashkevich , Daniil Ilyukhin , Arseniy Volkov , Valeria Yachnaya , Andrey Denisov , Maria Mikhalkova

Foundational language models show a remarkable ability to learn new concepts during inference via context data. However, similar work for images lag behind. To address this challenge, we introduce FLoWN, a flow matching model that learns to…

机器学习 · 计算机科学 2025-04-22 Daniel Saragih , Deyu Cao , Tejas Balaji , Ashwin Santhosh

Graph mining has become crucial in fields such as social science, finance, and cybersecurity. Many large-scale real-world networks exhibit both heterogeneity, where multiple node and edge types exist in the graph, and heterophily, where…

机器学习 · 计算机科学 2025-06-04 Junhong Lin , Xiaojie Guo , Shuaicheng Zhang , Yada Zhu , Julian Shun