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Monitoring diseases that affect the brain's structural integrity requires automated analysis of magnetic resonance (MR) images, e.g., for the evaluation of volumetric changes. However, many of the evaluation tools are optimized for…

Healthy tissue inpainting has significant applications, including the generation of pseudo-healthy baselines for tumor growth models and the facilitation of image registration. In previous editions of the BraTS Local Synthesis of Healthy…

图像与视频处理 · 电气工程与系统科学 2025-07-18 Alicia Durrer , Florentin Bieder , Paul Friedrich , Bjoern Menze , Philippe C. Cattin , Florian Kofler

Synthesizing healthy brain scans from diseased brain scans offers a potential solution to address the limitations of general-purpose algorithms, such as tissue segmentation and brain extraction algorithms, which may not effectively handle…

图像与视频处理 · 电气工程与系统科学 2024-02-05 Ruizhi Zhu , Xinru Zhang , Haowen Pang , Chundan Xu , Chuyang Ye

This paper introduces a novel approach to synthesize healthy 3D brain tissue from masked input images, specifically focusing on the task of 'ASNR-MICCAI BraTS Local Synthesis of Tissue via Inpainting'. Our proposed method employs a…

图像与视频处理 · 电气工程与系统科学 2025-07-25 Juexin Zhang , Ying Weng , Ke Chen

A myriad of algorithms for the automatic analysis of brain MR images is available to support clinicians in their decision-making. For brain tumor patients, the image acquisition time series typically starts with an already pathological…

图像与视频处理 · 电气工程与系统科学 2024-09-24 Florian Kofler , Felix Meissen , Felix Steinbauer , Robert Graf , Stefan K Ehrlich , Annika Reinke , Eva Oswald , Diana Waldmannstetter , Florian Hoelzl , Izabela Horvath , Oezguen Turgut , Suprosanna Shit , Christina Bukas , Kaiyuan Yang , Johannes C. Paetzold , Ezequiel de da Rosa , Isra Mekki , Shankeeth Vinayahalingam , Hasan Kassem , Juexin Zhang , Ke Chen , Ying Weng , Alicia Durrer , Philippe C. Cattin , Julia Wolleb , M. S. Sadique , M. M. Rahman , W. Farzana , A. Temtam , K. M. Iftekharuddin , Maruf Adewole , Syed Muhammad Anwar , Ujjwal Baid , Anastasia Janas , Anahita Fathi Kazerooni , Dominic LaBella , Hongwei Bran Li , Ahmed W Moawad , Gian-Marco Conte , Keyvan Farahani , James Eddy , Micah Sheller , Sarthak Pati , Alexandros Karagyris , Alejandro Aristizabal , Timothy Bergquist , Verena Chung , Russell Takeshi Shinohara , Farouk Dako , Walter Wiggins , Zachary Reitman , Chunhao Wang , Xinyang Liu , Zhifan Jiang , Elaine Johanson , Zeke Meier , Ariana Familiar , Christos Davatzikos , John Freymann , Justin Kirby , Michel Bilello , Hassan M Fathallah-Shaykh , Roland Wiest , Jan Kirschke , Rivka R Colen , Aikaterini Kotrotsou , Pamela Lamontagne , Daniel Marcus , Mikhail Milchenko , Arash Nazeri , Marc-André Weber , Abhishek Mahajan , Suyash Mohan , John Mongan , Christopher Hess , Soonmee Cha , Javier Villanueva-Meyer , Errol Colak , Priscila Crivellaro , Andras Jakab , Abiodun Fatade , Olubukola Omidiji , Rachel Akinola Lagos , O O Olatunji , Goldey Khanna , John Kirkpatrick , Michelle Alonso-Basanta , Arif Rashid , Miriam Bornhorst , Ali Nabavizadeh , Natasha Lepore , Joshua Palmer , Antonio Porras , Jake Albrecht , Udunna Anazodo , Mariam Aboian , Evan Calabrese , Jeffrey David Rudie , Marius George Linguraru , Juan Eugenio Iglesias , Koen Van Leemput , Spyridon Bakas , Benedikt Wiestler , Ivan Ezhov , Marie Piraud , Bjoern H Menze

Magnetic resonance imaging (MRI) inpainting supports numerous clinical and research applications. We introduce the first generative model that conditions on voxel-level, continuous tumor concentrations to synthesize high-fidelity brain…

图像与视频处理 · 电气工程与系统科学 2025-12-09 Valentin Biller , Lucas Zimmer , Ayhan Can Erdur , Sandeep Nagar , Daniel Rückert , Niklas Bubeck , Jonas Weidner

Recent advances in imaging and high-performance computing have made it possible to image the entire human brain at the cellular level. This is the basis to study the multi-scale architecture of the brain regarding its subdivision into brain…

图像与视频处理 · 电气工程与系统科学 2023-11-29 Jan-Oliver Kropp , Christian Schiffer , Katrin Amunts , Timo Dickscheid

The ASNR-MICCAI BraTS-Inpainting Challenge was established to mitigate dataset biases that limit deep learning models in the quantitative analysis of brain tumor MRI. This paper details our submission to the 2025 challenge, a novel deep…

计算机视觉与模式识别 · 计算机科学 2025-11-26 Juexin Zhang , Ying Weng , Ke Chen

Denoising diffusion models have recently achieved state-of-the-art performance in many image-generation tasks. They do, however, require a large amount of computational resources. This limits their application to medical tasks, where we…

计算机视觉与模式识别 · 计算机科学 2024-09-13 Florentin Bieder , Julia Wolleb , Alicia Durrer , Robin Sandkühler , Philippe C. Cattin

Recently, diffusion models were applied to a wide range of image analysis tasks. We build on a method for image-to-image translation using denoising diffusion implicit models and include a regression problem and a segmentation problem for…

计算机视觉与模式识别 · 计算机科学 2022-04-07 Julia Wolleb , Robin Sandkühler , Florentin Bieder , Philippe C. Cattin

Brain tumors delay the standard preprocessing workflow for further examination. Brain inpainting offers a viable, although difficult, solution for tumor tissue processing, which is necessary to improve the precision of the diagnosis and…

图像与视频处理 · 电气工程与系统科学 2025-02-25 Tianli Tao , Ziyang Wang , Han Zhang , Theodoros N. Arvanitis , Le Zhang

Deformable registration of magnetic resonance images between patients with brain tumors and healthy subjects has been an important tool to specify tumor geometry through location alignment and facilitate pathological analysis. Since tumor…

图像与视频处理 · 电气工程与系统科学 2021-01-19 Xiaofeng Liu , Fangxu Xing , Chao Yang , C. -C. Jay Kuo , Georges ElFakhri , Jonghye Woo

Automatic magnetic resonance (MR) image processing pipelines are widely used to study people with multiple sclerosis (PwMS), encompassing tasks such as lesion segmentation and brain parcellation. However, the presence of lesion often…

图像与视频处理 · 电气工程与系统科学 2024-10-08 Jinwei Zhang , Lianrui Zuo , Yihao Liu , Samuel Remedios , Bennett A. Landman , Jerry L. Prince , Aaron Carass

Accurate longitudinal analysis of brain MRI is often hindered by evolving lesions, which bias automated neuroimaging pipelines. While deep generative models have shown promise in inpainting these lesions, most existing methods operate…

图像与视频处理 · 电气工程与系统科学 2026-03-09 Zahra Karimaghaloo , Dumitru Fetco , Haz-Edine Assemlal , Hassan Rivaz , Douglas L. Arnold

Predicting the spatio-temporal progression of brain tumors is essential for guiding clinical decisions in neuro-oncology. We propose a hybrid mechanistic learning framework that combines a mathematical tumor growth model with a guided…

计算机视觉与模式识别 · 计算机科学 2025-09-12 Daria Laslo , Efthymios Georgiou , Marius George Linguraru , Andreas Rauschecker , Sabine Muller , Catherine R. Jutzeler , Sarah Bruningk

Despite the ever-increasing interest in applying deep learning (DL) models to medical imaging, the typical scarcity and imbalance of medical datasets can severely impact the performance of DL models. The generation of synthetic data that…

图像与视频处理 · 电气工程与系统科学 2023-04-03 Pouria Rouzrokh , Bardia Khosravi , Shahriar Faghani , Mana Moassefi , Sanaz Vahdati , Bradley J. Erickson

Magnetic Resonance Imaging (MRI) is the primary imaging modality used in the diagnosis, assessment, and treatment planning for brain pathologies. However, most automated MRI analysis tools, such as segmentation and registration pipelines,…

Computational neuroimaging involves analyzing brain images or signals to provide mechanistic insights and predictive tools for human cognition and behavior. While diffusion models have shown stability and high-quality generation in natural…

计算机视觉与模式识别 · 计算机科学 2025-02-11 Haokai Zhao , Haowei Lou , Lina Yao , Wei Peng , Ehsan Adeli , Kilian M Pohl , Yu Zhang

Tumor segmentation from multi-modal brain MRI images is a challenging task due to the limited samples, high variance in shapes and uneven distribution of tumor morphology. The performance of automated medical image segmentation has been…

图像与视频处理 · 电气工程与系统科学 2024-02-13 Tianyi Ren , Ethan Honey , Harshitha Rebala , Abhishek Sharma , Agamdeep Chopra , Mehmet Kurt

Brain tumors require an assessment to ensure timely diagnosis and effective patient treatment. Morphological factors such as size, location, texture, and variable appearance complicate tumor inspection. Medical imaging presents challenges,…

计算机视觉与模式识别 · 计算机科学 2025-06-27 Md. Zahid Hasan , Abdullah Tamim , D. M. Asadujjaman , Md. Mahfujur Rahman , Md. Abu Ahnaf Mollick , Nosin Anjum Dristi , Abdullah-Al-Noman
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