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Abstruse learning algorithms and complex datasets increasingly characterize modern clinical decision support systems (CDSS). As a result, clinicians cannot easily or rapidly scrutinize the CDSS recommendation when facing a difficult…

人工智能 · 计算机科学 2021-11-02 Bojian Hou , Hao Zhang , Gur Ladizhinsky , Gur Ladizhinsky , Stephen Yang , Volodymyr Kuleshov , Fei Wang , Qian Yang

Existing Clinical Decision Support Systems (CDSSs) largely depend on the availability of structured patient data and Electronic Health Records (EHRs) to aid caregivers. However, in case of hospitals in developing countries, structured…

计算与语言 · 计算机科学 2019-11-27 Gokul S Krishnan , Sowmya Kamath S

With the increasing availability of patient data, modern medicine is shifting towards prospective healthcare. Electronic health records offer a variety of information useful for clinical patient characterization and the development of…

机器学习 · 计算机科学 2025-05-27 Fabio Azzalini , Tommaso Dolci , Marco Vagaggini

To facilitate healthcare delivery, language models (LMs) have significant potential for clinical prediction tasks using electronic health records (EHRs). However, in these high-stakes applications, unreliable decisions can result in high…

计算与语言 · 计算机科学 2024-11-07 Zizhang Chen , Peizhao Li , Xiaomeng Dong , Pengyu Hong

Continuous diagnosis and prognosis are essential for intensive care patients. It can provide more opportunities for timely treatment and rational resource allocation, especially for sepsis, a main cause of death in ICU, and COVID-19, a new…

机器学习 · 计算机科学 2022-10-07 Chenxi Sun , Hongyan Li , Moxian Song , Derun Cai , Baofeng Zhang , Shenda Hong

We study aleatoric and epistemic uncertainty estimation in a learned regressive system dynamics model. Disentangling aleatoric uncertainty (the inherent randomness of the system) from epistemic uncertainty (the lack of data) is crucial for…

机器学习 · 计算机科学 2025-03-21 Zhiyu An , Zhibo Hou , Wan Du

Clinical trials are a systematic endeavor to assess the safety and efficacy of new drugs or treatments. Conducting such trials typically demands significant financial investment and meticulous planning, highlighting the need for accurate…

机器学习 · 计算机科学 2025-11-03 Tien Huu Do , Antoine Masquelier , Nae Eoun Lee , Jonathan Crowther

Clinical Decision Support Systems (CDSS) utilize evidence-based knowledge and patient data to offer real-time recommendations, with Large Language Models (LLMs) emerging as a promising tool to generate plain-text explanations for medical…

计算与语言 · 计算机科学 2023-10-04 D. Umerenkov , G. Zubkova , A. Nesterov

In a data-scarce field such as healthcare, where models often deliver predictions on patients with rare conditions, the ability to measure the uncertainty of a model's prediction could potentially lead to improved effectiveness of decision…

机器学习 · 统计学 2020-05-26 Lotta Meijerink , Giovanni Cinà , Michele Tonutti

Clinical decision support systems combine knowledge and data from a variety of sources, represented by quantitative models based on stochastic methods, or qualitative based rather on expert heuristics and deductive reasoning. At the same…

人工智能 · 计算机科学 2020-01-22 Ying Shen , Jacquet-Andrieu Armelle , Joël Colloc

The paper presents an approach for building consistent and applicable clinical decision support systems (CDSSs) using a data-driven predictive model aimed at resolving the problem of low applicability and scalability of CDSSs in real-world…

人工智能 · 计算机科学 2022-02-18 Sergey V. Kovalchuk , Georgy D. Kopanitsa , Ilia V. Derevitskii , Daria A. Savitskaya

International Classification of Diseases (ICD) are the de facto codes used globally for clinical coding. These codes enable healthcare providers to claim reimbursement and facilitate efficient storage and retrieval of diagnostic…

计算与语言 · 计算机科学 2022-02-22 Pavithra Rajendran , Alexandros Zenonos , Josh Spear , Rebecca Pope

Deep neural networks (DNNs) have made a revolution in numerous fields during the last decade. However, in tasks with high safety requirements, such as medical or autonomous driving applications, providing an assessment of the models…

机器学习 · 计算机科学 2020-11-20 Omer Achrack , Raizy Kellerman , Ouriel Barzilay

In real-world clinical settings, data distributions evolve over time, with a continuous influx of new, limited disease cases. Therefore, class incremental learning is of great significance, i.e., deep learning models are required to learn…

计算机视觉与模式识别 · 计算机科学 2024-09-13 Yifei Yao , Hanrong Zhang

Trustworthy artificial intelligence (AI) is essential in healthcare, particularly for high-stakes tasks like medical image segmentation. Explainable AI and uncertainty quantification significantly enhance AI reliability by addressing key…

The objective of this work is to develop an Electronic Medical Record (EMR) data processing tool that confers clinical context to Machine Learning (ML) algorithms for error handling, bias mitigation and interpretability. We present…

Clinical coding is the task of transforming medical information in a patient's health records into structured codes so that they can be used for statistical analysis. This is a cognitive and time-consuming task that follows a standard…

计算与语言 · 计算机科学 2022-10-11 Hang Dong , Matúš Falis , William Whiteley , Beatrice Alex , Joshua Matterson , Shaoxiong Ji , Jiaoyan Chen , Honghan Wu

This research focuses on evaluating and enhancing data readiness for the development of an Artificial Intelligence (AI)-based Clinical Decision Support System (CDSS) in the context of skin cancer treatment. The study, conducted at the Skin…

We propose a novel and interpretable embedding method to represent the international statistical classification codes of diseases and related health problems (i.e., ICD codes). This method considers a self-attention mechanism within the…

应用统计 · 统计学 2019-06-14 Dixin Luo , Hongteng Xu , Lawrence Carin

Recent efforts in Machine Learning (ML) interpretability have focused on creating methods for explaining black-box ML models. However, these methods rely on the assumption that simple approximations, such as linear models or decision-trees,…

机器学习 · 计算机科学 2019-06-13 Owen Lahav , Nicholas Mastronarde , Mihaela van der Schaar