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Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

计算机与社会 · 计算机科学 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

LLM-based agents have emerged as transformative tools capable of executing complex tasks through iterative planning and action, achieving significant advancements in understanding and addressing user needs. Yet, their effectiveness remains…

人机交互 · 计算机科学 2025-08-26 Mithat Can Ozgun , Jiahuan Pei , Koen Hindriks , Lucia Donatelli , Qingzhi Liu , Junxiao Wang

Artificial intelligence (AI) methods have become critical in scientific applications to help accelerate scientific discovery. Large language models (LLMs) are being considered as a promising approach to address some of the challenging…

Recent advances in Retrieval-Augmented Generation (RAG) have enabled large language models (LLMs) to ground outputs in clinical evidence. However, connecting LLMs with external databases introduces the risk of contextual leakage: a subtle…

计算与语言 · 计算机科学 2026-03-17 Shaowei Guan , Yu Zhai , Hin Chi Kwok , Jiawei Du , Xinyu Feng , Jing Li , Harry Qin , Vivian Hui

In this study, we introduce PharmacyGPT, a novel framework to assess the capabilities of large language models (LLMs) such as ChatGPT and GPT-4 in emulating the role of clinical pharmacists. Our methodology encompasses the utilization of…

Large Language Models (LLMs) have brought huge improvements to Artificial Intelligence (AI), which can be applied to general-purpose tasks. However, their application to textual or spoken medical consultations is still an open research…

人工智能 · 计算机科学 2026-05-27 Heriberto Cuayahuitl , Grace Jang

Autonomous agents utilizing Large Language Models (LLMs) have demonstrated remarkable capabilities in isolated medical tasks like diagnosis and image analysis, but struggle with integrated clinical workflows that connect diagnostic…

人工智能 · 计算机科学 2025-10-14 Hongjie Zheng , Zesheng Shi , Ping Yi

Recent advances in medical large language models (LLMs), multimodal models, and agents demand evaluation frameworks that reflect real clinical workflows and safety constraints. We present MedBench v4, a nationwide, cloud-based benchmarking…

In recent years, interest has arisen in using machine learning to improve the efficiency of automatic medical consultation and enhance patient experience. In this article, we propose two frameworks to support automatic medical consultation,…

计算与语言 · 计算机科学 2022-12-27 Wei Chen , Zhiwei Li , Hongyi Fang , Qianyuan Yao , Cheng Zhong , Jianye Hao , Qi Zhang , Xuanjing Huang , Jiajie Peng , Zhongyu Wei

Multimodal Large Language Models (MLLMs) have tremendous potential to improve the accuracy, availability, and cost-effectiveness of healthcare by providing automated solutions or serving as aids to medical professionals. Despite promising…

计算机视觉与模式识别 · 计算机科学 2025-05-22 Mohammad Shahab Sepehri , Zalan Fabian , Maryam Soltanolkotabi , Mahdi Soltanolkotabi

Large Language Models (LLMs) are increasingly deployed in healthcare, yet their communicative alignment with clinical standards remains insufficiently quantified. We conduct a multidimensional evaluation of general-purpose and…

The simulation of realistic clinical interactions plays a pivotal role in advancing clinical Large Language Models (LLMs) and supporting medical diagnostic education. Existing approaches and benchmarks rely on generic or LLM-generated…

计算与语言 · 计算机科学 2026-01-19 Shijie Jiang , Zefan Zhang , Kehua Zhu , Tian Bai , Ruihong Zhao

An effective healthcare agent must be able to recall and reason over a patient's longitudinal medical history. However, the absence of datasets with realistic long-term dialogue timelines limits systematic evaluation. Real clinical text is…

计算与语言 · 计算机科学 2026-05-20 Hebin Hu , Renke Dai , Ah-Hwee Tan , Yilin Kang

In an era defined by the explosive growth of data and rapid technological advancements, Multimodal Large Language Models (MLLMs) stand at the forefront of artificial intelligence (AI) systems. Designed to seamlessly integrate diverse data…

The literature and multiple experts point to many potential risks from large language models (LLMs), but there are still very few direct measurements of the actual harms posed. AI risk assessment has so far focused on measuring the models'…

人工智能 · 计算机科学 2025-03-11 Malcolm Murray , Henry Papadatos , Otter Quarks , Pierre-François Gimenez , Simeon Campos

Large language models (LLMs) have demonstrated remarkable performance on various medical benchmarks, but their capabilities across different cognitive levels remain underexplored. Inspired by Bloom's Taxonomy, we propose a…

计算与语言 · 计算机科学 2025-06-11 Yuxuan Zhou , Xien Liu , Chenwei Yan , Chen Ning , Xiao Zhang , Boxun Li , Xiangling Fu , Shijin Wang , Guoping Hu , Yu Wang , Ji Wu

Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the…

计算机视觉与模式识别 · 计算机科学 2025-05-13 Chao Ding , Mouxiao Bian , Pengcheng Chen , Hongliang Zhang , Tianbin Li , Lihao Liu , Jiayuan Chen , Zhuoran Li , Yabei Zhong , Yongqi Liu , Haiqing Huang , Dongming Shan , Junjun He , Jie Xu

The rapid rise in popularity of Large Language Models (LLMs) with emerging capabilities has spurred public curiosity to evaluate and compare different LLMs, leading many researchers to propose their own LLM benchmarks. Noticing preliminary…

人工智能 · 计算机科学 2025-05-15 Timothy R. McIntosh , Teo Susnjak , Nalin Arachchilage , Tong Liu , Paul Watters , Malka N. Halgamuge

Large language models (LLMs) have immense potential to make information more accessible, particularly in medicine, where complex medical jargon can hinder patient comprehension of clinical notes. We developed a patient-facing tool using…

Recent advancements in reasoning-enhanced large language models (LLMs), such as DeepSeek-R1 and OpenAI-o3, have demonstrated significant progress. However, their application in professional medical contexts remains underexplored,…

计算与语言 · 计算机科学 2025-03-11 Pengcheng Qiu , Chaoyi Wu , Shuyu Liu , Weike Zhao , Zhuoxia Chen , Hongfei Gu , Chuanjin Peng , Ya Zhang , Yanfeng Wang , Weidi Xie
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