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In this paper, we review physics- and data-driven reconstruction techniques for simultaneous positron emission tomography (PET) / magnetic resonance imaging (MRI) systems, which have significant advantages for clinical imaging of cancer,…

图像与视频处理 · 电气工程与系统科学 2022-06-15 Abhejit Rajagopal , Andrew P. Leynes , Nicholas Dwork , Jessica E. Scholey , Thomas A. Hope , Peder E. Z. Larson

Positron emission tomography (PET) is widely utilized for cancer detection due to its ability to visualize functional and biological processes in vivo. PET images are usually reconstructed from histogrammed raw data (sinograms) using…

图像与视频处理 · 电气工程与系统科学 2024-11-26 Yiran Sun , Osama Mawlawi

A major remaining challenge for magnetic resonance-based attenuation correction methods (MRAC) is their susceptibility to sources of MRI artifacts (e.g. implants, motion) and uncertainties due to the limitations of MRI contrast (e.g.…

In clinical practice, single-radiotracer positron emission tomography (PET) is commonly used for imaging. Although multi-tracer PET imaging can provide supplementary information of radiotracers that are sensitive to physiological function…

图像与视频处理 · 电气工程与系统科学 2025-06-23 Bin Huang , Feihong Xu , Xinchong Shi , Shan Huang , Binxuan Li , Fei Li , Qiegen Liu

While various deep learning methods were proposed for low-dose computed tomography (CT) denoising, they often suffer from over-smoothing, blurring, and lack of explainability. To alleviate these issues, we propose a plug-and-play…

图像与视频处理 · 电气工程与系统科学 2024-03-12 Zhihao Chen , Tao Chen , Chenhui Wang , Chuang Niu , Ge Wang , Hongming Shan

Anatomically guided PET reconstruction using MRI information has been shown to have the potential to improve PET image quality. However, these improvements are limited to PET scans with paired MRI information. In this work we employed a…

Many current neural networks for medical imaging generalise poorly to data unseen during training. Such behaviour can be caused by networks overfitting easy-to-learn, or statistically dominant, features while disregarding other potentially…

图像与视频处理 · 电气工程与系统科学 2022-12-05 Joona Pohjonen , Carolin Stürenberg , Antti Rannikko , Tuomas Mirtti , Esa Pitkänen

Lymphoma detection and segmentation from whole-body Positron Emission Tomography/Computed Tomography (PET/CT) volumes are crucial for surgical indication and radiotherapy. Designing automatic segmentation methods capable of effectively…

图像与视频处理 · 电气工程与系统科学 2021-08-29 Ling Huang , Thierry Denoeux , David Tonnelet , Pierre Decazes , Su Ruan

Over the past decades, thermal ablation procedures such as high intensity focused ultrasound (HIFU) have been developed vaporize cancerous tissues in a focal area. Thermal ablation has the potential to non-invasively eliminate tumors and…

医学物理 · 物理学 2022-03-01 Nathan Wang , Petteri Haverinen

The objective of this study was to develop a PET tumor-segmentation framework that addresses the challenges of limited spatial resolution, high image noise, and lack of clinical training data with ground-truth tumor boundaries in PET…

Spectral CT offers enhanced material discrimination over single-energy systems and enables quantitative estimation of basis material density images. Water/iodine decomposition in contrast-enhanced CT is one of the most widespread…

医学物理 · 物理学 2021-03-30 Matthew Tivnan , Grace Gang , Wenchao Cao , Nadav Shapira , Peter B. Noel , J. Webster Stayman

Dual-energy X-ray absorptiometry (DEXA) has been widely applied to measure bone mineral density (BMD) and soft-tissue composition of human body. However, the use of DEXA is greatly limited for low-Z materials such as soft tissues due to…

医学物理 · 物理学 2016-02-18 Huajie Han , Shenghao Wang , Kun Gao , Zhili Wang , Can Zhang , Meng Yang , Kai Zhang , Peiping Zhu

Computed tomography (CT) scans offer a detailed, three-dimensional representation of patients' internal organs. However, conventional CT reconstruction techniques necessitate acquiring hundreds or thousands of x-ray projections through a…

图像与视频处理 · 电气工程与系统科学 2023-11-27 Chulong Zhang , Lin Liu , Jingjing Dai , Xuan Liu , Wenfeng He , Yinping Chan , Yaoqin Xie , Feng Chi , Xiaokun Liang

Noise and artifacts during computed tomography (CT) scans are a fundamental challenge affecting disease diagnosis. However, current methods either involve excessively long reconstruction times or rely on data-driven models for optimization,…

计算机视觉与模式识别 · 计算机科学 2026-03-03 Guoquan Wei , Liu Shi , Shaoyu Wang , Mohan Li , Cunfeng Wei , Qiegen Liu

While medical images such as computed tomography (CT) are stored in DICOM format in hospital PACS, it is still quite routine in many countries to print a film as a transferable medium for the purposes of self-storage and secondary…

图像与视频处理 · 电气工程与系统科学 2022-03-14 Quan Quan , Qiyuan Wang , Yuanqi Du , Liu Li , S. Kevin Zhou

Dual-energy (DE) chest radiographs provide greater diagnostic information than standard radiographs by separating the image into bone and soft tissue, revealing suspicious lesions which may otherwise be obstructed from view. However,…

计算机视觉与模式识别 · 计算机科学 2021-04-15 Bo Zhou , Xunyu Lin , Brendan Eck , Jun Hou , David L. Wilson

Photon-Counting Computed Tomography (PCCT) is a novel imaging modality that simultaneously acquires volumetric data at multiple X-ray energy levels, generating separate volumes that capture energy-dependent attenuation properties.…

人机交互 · 计算机科学 2025-08-21 Mohit Sharma , Emma Nilsson , Martin Falk , Talha Bin Masood , Lee Jollans , Anders Persson , Tino Ebbers , Ingrid Hotz

The ability to synthesise Computed Tomography images - commonly known as pseudo CT, or pCT - from MRI input data is commonly assessed using an intensity-wise similarity, such as an L2-norm between the ground truth CT and the pCT. However,…

Spectral computed tomography (CT) with photon-counting detectors holds immense potential for material discrimination and tissue characterization. However, under ultra-low-dose conditions, the sharply degraded signal-to-noise ratio (SNR) in…

计算机视觉与模式识别 · 计算机科学 2026-02-10 Peng Peng , Xinrui Zhang , Junlin Wang , Lei Li , Shaoyu Wang , Qiegen Liu

Multi-material decomposition (MMD) enables quantitative reconstruction of tissue compositions in the human body, supporting a wide range of clinical applications. However, traditional MMD typically requires spectral CT scanners and…

计算机视觉与模式识别 · 计算机科学 2025-05-14 Qing Wu , Hongjiang Wei , Jingyi Yu , S. Kevin Zhou , Yuyao Zhang