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Large Language Models (LLMs) have exhibited remarkable performance on various Natural Language Processing (NLP) tasks. However, there is a current hot debate regarding their reasoning capacity. In this paper, we examine the performance of…

Can ChatGPT diagnose Alzheimer's Disease (AD)? AD is a devastating neurodegenerative condition that affects approximately 1 in 9 individuals aged 65 and older, profoundly impairing memory and cognitive function. This paper utilises 9300…

机器学习 · 计算机科学 2025-02-12 Quoc-Toan Nguyen , Linh Le , Xuan-The Tran , Thomas Do , Chin-Teng Lin

Alzheimer's dementia (AD) is a neurodegenerative disorder with cognitive decline that commonly impacts language ability. This work extends the paired perplexity approach to detecting AD by using a recent large language model (LLM), the…

计算与语言 · 计算机科学 2025-06-12 Yao Xiao , Heidi Christensen , Stefan Goetze

Alzheimer's Disease (AD) is a significant and growing public health concern. Investigating alterations in speech and language patterns offers a promising path towards cost-effective and non-invasive early detection of AD on a large scale.…

计算与语言 · 计算机科学 2024-12-23 Jonathan Heitz , Gerold Schneider , Nicolas Langer

Societies worldwide are rapidly entering a super-aged era, making elderly health a pressing concern. The aging population is increasing the burden on national economies and households. Dementia cases are rising significantly with this…

人工智能 · 计算机科学 2025-06-03 Chanwoo Park , Anna Seo Gyeong Choi , Sunghye Cho , Chanwoo Kim

In the past two years, large language model (LLM)-based chatbots, such as ChatGPT, have revolutionized various domains by enabling diverse task completion and question-answering capabilities. However, their application in scientific…

Alzheimer's disease (AD) has become a prevalent neurodegenerative disease worldwide. Traditional diagnosis still relies heavily on medical imaging and clinical assessment by physicians, which is often time-consuming and resource-intensive…

计算与语言 · 计算机科学 2026-02-17 Tongze Zhang , Jun-En Ding , Melik Ozolcer , Fang-Ming Hung , Albert Chih-Chieh Yang , Feng Liu , Yi-Rou Ji , Sang Won Bae

Alzheimer's Disease (AD) is an irreversible neurodegenerative disease affecting 50 million people worldwide. Low-cost, accurate identification of key markers of AD is crucial for timely diagnosis and intervention. Language impairment is one…

计算与语言 · 计算机科学 2025-05-27 Tingyu Mo , Jacqueline C. K. Lam , Victor O. K. Li , Lawrence Y. L. Cheung

Previous researchers have proposed intelligent systems for therapeutic monitoring of cognitive impairments. However, most existing practical approaches for this purpose are based on manual tests. This raises issues such as excessive…

Large language models (LLMs) have emerged as powerful tools for medical information retrieval, yet their accuracy and depth remain limited in specialized domains such as Alzheimer's disease (AD), a growing global health challenge. To…

Research related to automatically detecting Alzheimer's disease (AD) is important, given the high prevalence of AD and the high cost of traditional methods. Since AD significantly affects the content and acoustics of spontaneous speech,…

计算与语言 · 计算机科学 2020-08-05 Aparna Balagopalan , Benjamin Eyre , Frank Rudzicz , Jekaterina Novikova

Large language models (LLMs) have shown great potential for healthcare applications. However, existing evaluation benchmarks provide minimal coverage of Alzheimer's Disease and Related Dementias (ADRD). To address this gap, we introduce…

计算与语言 · 计算机科学 2026-05-27 Guangxin Zhao , Jiahao Zheng , Malaz Boustani , Jarek Nabrzyski , Yiyu Shi , Meng Jiang , Zhi Zheng

In this paper, we propose a natural language processing architecture that can handle tasks that previously required two models as one model. With a single model, we analyze the language patterns and conversational context of Alzheimer's…

计算与语言 · 计算机科学 2022-11-16 Park Jun Yeong , Shin Su Jong , Choi Chang Hwan , Lee Jung Jae , Choi Sang-il

Background: Alzheimer's disease and related dementias (ADRD) are progressive neurodegenerative conditions where early detection is vital for timely intervention and care. Spontaneous speech contains rich acoustic and linguistic markers that…

计算与语言 · 计算机科学 2025-06-16 Jingyu Li , Lingchao Mao , Hairong Wang , Zhendong Wang , Xi Mao , Xuelei Sherry Ni

Large language models (LLM) have been successful in several natural language understanding tasks and could be relevant for natural language processing (NLP)-based mental health application research. In this work, we report the performance…

计算与语言 · 计算机科学 2023-03-29 Bishal Lamichhane

Alzheimer's Dementia (AD) is an incurable, debilitating, and progressive neurodegenerative condition that affects cognitive function. Early diagnosis is important as therapeutics can delay progression and give those diagnosed vital time.…

机器学习 · 计算机科学 2023-02-28 Thomas Searle , Zina Ibrahim , Richard Dobson

Several machine learning algorithms have been developed for the prediction of Alzheimer's disease and related dementia (ADRD) from spontaneous speech. However, none of these algorithms have been translated for the prediction of broader…

This paper investigates the use of artificial intelligence chatbots for patient-specific question answering (QA) from clinical notes using several large language model (LLM) based systems: ChatGPT (versions 3.5 and 4), Google Bard, and…

计算与语言 · 计算机科学 2023-06-06 Alaleh Hamidi , Kirk Roberts

ChatGPT and Bard are AI chatbots based on Large Language Models (LLM) that are slated to promise different applications in diverse areas. In education, these AI technologies have been tested for applications in assessment and teaching. In…

计算与语言 · 计算机科学 2023-05-11 Abdolvahab Khademi

Purpose: Enhanced health literacy has been linked to better health outcomes; however, few interventions have been studied. We investigate whether large language models (LLMs) can serve as a medium to improve health literacy in children and…

计算与语言 · 计算机科学 2023-11-17 Kanhai S. Amin , Linda Mayes , Pavan Khosla , Rushabh Doshi
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