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Any process in which competing solutions replicate with errors and numbers of their copies depend on their respective fitnesses is the evolutionary optimization process. As during carcinogenesis mutated genomes replicate according to their…

种群与进化 · 定量生物学 2009-12-15 B. Brutovsky , D. Horvath

Generative molecular design has moved from proof-of-concept to real-world applicability, as marked by the surge in very recent papers reporting experimental validation. Key challenges in explainability and sample efficiency present…

生物大分子 · 定量生物学 2024-03-05 Jeff Guo , Philippe Schwaller

This paper introduces a methodology designed to augment the inverse design optimization process in scenarios constrained by limited compute, through the strategic synergy of multi-fidelity evaluations, machine learning models, and…

计算工程、金融与科学 · 计算机科学 2024-06-04 Luka Grbcic , Juliane Müller , Wibe Albert de Jong

The performance bottleneck of deep-learning-based recommender systems resides in their backbone Deep Neural Networks. By integrating Processing-In-Memory~(PIM) architectures, researchers can reduce data movement and enhance energy…

硬件体系结构 · 计算机科学 2025-05-19 Feng Cheng , Tunhou Zhang , Junyao Zhang , Jonathan Hao-Cheng Ku , Yitu Wang , Xiaoxuan Yang , Hai , Li , Yiran Chen

We apply kernel mean embedding methods to sample-based stochastic optimization and control. Specifically, we use the reduced-set expansion method as a way to discard sampled scenarios. The effect of such constraint removal is improved…

最优化与控制 · 数学 2020-04-24 Jia-Jie Zhu , Moritz Diehl , Bernhard Schölkopf

Optimization strategies driven by machine learning, such as Bayesian optimization, are being explored across experimental sciences as an efficient alternative to traditional design of experiment. When combined with automated laboratory…

最优化与控制 · 数学 2022-10-18 Riley J. Hickman , Matteo Aldeghi , Florian Häse , Alán Aspuru-Guzik

Hyperledger Fabric (HLF) is a modular, permissioned blockchain widely adopted in enterprise settings. Enhancing its throughput and latency remains challenging, as optimization decisions made in one phase of the transaction lifecycle can…

分布式、并行与集群计算 · 计算机科学 2026-05-01 Pavan Sollu , Aniruddha Mukherjee , Divya Pulivarthi , S. R. Eshwar , Gugan Thoppe , Kshitij Pratihast , Tittu Varghese , Hrishikesh Nashikkar , Yogesh Simmhan

This paper reports on continuing research into the modelling of an order picking process within a Crossdocking distribution centre using Simulation Optimisation. The aim of this project is to optimise a discrete event simulation model and…

人工智能 · 计算机科学 2010-07-05 Adrian Adewunmi , Uwe Aickelin

As global attention on renewable and clean energy grows, the research and implementation of microgrids become paramount. This paper delves into the methodology of exploring the relationship between the operational and environmental costs of…

人工智能 · 计算机科学 2023-10-04 Hongyi Duan , Qingyang Li , Yuchen Li , Jianan Zhang , Yuming Xie

Spiking Neural Networks (SNNs) are promising biologically plausible models of computation which utilize a spiking binary activation function similar to that of biological neurons. SNNs are well positioned to process spatiotemporal data, and…

神经与进化计算 · 计算机科学 2025-05-20 Boxun Xu , Richard Boone , Peng Li

We examine the problem of optimal design in the context of filtering multiple random walks. Specifically, we define the steady state E-optimal design criterion and show that the underlying optimization problem leads to a second order cone…

应用统计 · 统计学 2010-10-07 Harsh Singhal , George Michailidis

Plant breeding programs use data obtained from multi-environment selection experiments to produce improved varieties with the ultimate aim of maintaining high levels of genetic gain. Selection accuracy can be improved with the use of…

统计方法学 · 统计学 2026-05-13 Brian R Cullis , Alison B Smith , David GD Hughes , David Butler

Speculative decoding (SD) accelerates large language model inference by employing a faster draft model for generating multiple tokens, which are then verified in parallel by the larger target model, resulting in the text generated according…

To improve decision-making and planning efficiency in back-end centralized redundant supply chains, this paper proposes a decision model integrating deep learning with intelligent particle swarm optimization. A distributed node deployment…

机器学习 · 计算机科学 2025-11-04 Shiman Zhang , Jinghan Zhou , Zhoufan Yu , Ningai Leng

Bio-Inspired computing is the subset of Nature-Inspired computing. Job Shop Scheduling Problem is categorized under popular scheduling problems. In this research work, Bacterial Foraging Optimization was hybridized with Ant Colony…

神经与进化计算 · 计算机科学 2012-11-22 S. Narendhar , T. Amudha

At submicron manufacturing technology nodes, pro- cess variations affect circuit performance significantly. To counter these variations, engineers are reserving more timing margin to maintain yield, leading to an unaffordable overdesign.…

硬件体系结构 · 计算机科学 2017-05-16 Li Zhang , Bing Li , Jinglan Liu , Yiyu Shi , Ulf Schlichtmann

The aim of this study is to give insights into the trajectory optimization w.r.t. energy consumption and recuperation for stacker cranes in a high-bay warehouse. Based on an analytical necessary optimality condition, a targeted numerical…

最优化与控制 · 数学 2026-02-05 R. Zöllner , F. Schuricht , T. Schmidt , W. Hofmann

The concept of concurrent material and structure optimization aims at alleviating the computational discovery of optimum microstructure configurations in multiphase hierarchical systems, whose macroscale behavior is governed by their…

计算物理 · 物理学 2022-04-15 Tarun Gangwar , Dominik Schillinger

Uncertainty quantification has become an efficient tool for uncertainty-aware prediction, but its power in yield-aware optimization has not been well explored from either theoretical or application perspectives. Yield optimization is a much…

最优化与控制 · 数学 2020-04-28 Chunfeng Cui , Kaikai Liu , Zheng Zhang

In today competitive business environment, efficient logistics are essential, especially in industries where timely delivery matters. This research aims to improve warehouse picking cycle time through simulation-based analysis, using a…

系统与控制 · 电气工程与系统科学 2025-11-13 Phattara Khumprom , Wanatchapong Kongkaew , Antoun Yaacoub , Nattakit Thanawitsatien