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We present EHRMIND, a practical recipe for adapting large language models (LLMs) to complex clinical reasoning tasks using reinforcement learning with verifiable rewards (RLVR). While RLVR has succeeded in mathematics and coding, its…

计算与语言 · 计算机科学 2025-06-02 Jiacheng Lin , Zhenbang Wu , Jimeng Sun

Electronic Health Records (EHRs) provide rich longitudinal clinical evidence that is central to medical decision-making, motivating the use of retrieval-augmented generation (RAG) to ground large language model (LLM) predictions. However,…

人工智能 · 计算机科学 2026-01-30 Lang Cao , Qingyu Chen , Yue Guo

Electronic Health Records (EHRs) and routine documentation practices play a vital role in patients' daily care, providing a holistic record of health, diagnoses, and treatment. However, complex and verbose EHR narratives overload healthcare…

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

计算机与社会 · 计算机科学 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

Recent advances in Large Language Models (LLMs) have led to remarkable progresses in medical consultation. However, existing medical LLMs overlook the essential role of Electronic Health Records (EHR) and focus primarily on diagnosis…

人工智能 · 计算机科学 2025-06-26 Weijieying Ren , Tianxiang Zhao , Lei Wang , Tianchun Wang , Vasant Honavar

Formulating a treatment plan is inherently a complex reasoning and refinement task rather than a simple generation problem. However, existing large language models (LLMs) mainly rely on one-shot output without explicit verification, which…

人工智能 · 计算机科学 2026-05-08 Junkai Li , Yunghwei Lai , Tianyi Zhu , Zheng Long Lee , Weizhi Ma , Yang Liu

The integration of multimodal Electronic Health Records (EHR) data has significantly improved clinical predictive capabilities. Leveraging clinical notes and multivariate time-series EHR, existing models often lack the medical context…

人工智能 · 计算机科学 2024-02-13 Yinghao Zhu , Changyu Ren , Shiyun Xie , Shukai Liu , Hangyuan Ji , Zixiang Wang , Tao Sun , Long He , Zhoujun Li , Xi Zhu , Chengwei Pan

Electronic health records (EHRs) are central to modern healthcare delivery and research; yet, many researchers lack the database expertise necessary to write complex SQL queries or generate effective visualizations, limiting efficient data…

Electronic health records (EHRs) contain vast amounts of complex data, but harmonizing and processing this information remains a challenging and costly task requiring significant clinical expertise. While large language models (LLMs) have…

计算与语言 · 计算机科学 2024-07-02 João Matos , Jack Gallifant , Jian Pei , A. Ian Wong

Accurate and efficient question-answering systems are essential for delivering high-quality patient care in the medical field. While Large Language Models (LLMs) have made remarkable strides across various domains, they continue to face…

计算与语言 · 计算机科学 2025-01-22 Hang Yang , Hao Chen , Hui Guo , Yineng Chen , Ching-Sheng Lin , Shu Hu , Jinrong Hu , Xi Wu , Xin Wang

Medical Decision-Making (MDM) is a multi-faceted process that requires clinicians to assess complex multi-modal patient data patient, often collaboratively. Large Language Models (LLMs) promise to streamline this process by synthesizing…

Large Language Models (LLMs) have become a key topic in AI and NLP, transforming sectors like healthcare, finance, education, and marketing by improving customer service, automating tasks, providing insights, improving diagnostics, and…

人工智能 · 计算机科学 2025-12-05 Vignesh Kumar Kembu , Pierandrea Morandini , Marta Bianca Maria Ranzini , Antonino Nocera

Electronic health records (EHR) contain extensive structured and unstructured data, including tabular information and free-text clinical notes. Querying relevant patient information often requires complex database operations, increasing the…

信息检索 · 计算机科学 2025-11-27 Mengliang ZHang

The introduction of Large Language Models (LLMs) has advanced data representation and analysis, bringing significant progress in their use for medical questions and answering. Despite these advancements, integrating tabular data, especially…

Clinical decision-making is inherently complex and fast-paced, particularly in emergency departments (EDs) where critical, rapid and high-stakes decisions are made. Clinical Decision Rules (CDRs) are standardized evidence-based tools that…

Scientific research indicates that for every hour spent in direct patient care, physicians spend nearly two additional hours on administrative tasks, particularly on electronic health records (EHRs) and desk work. This excessive…

计算与语言 · 计算机科学 2025-09-25 Hui Yi Leong , Yi Fan Gao , Ji Shuai , Yang Zhang , Uktu Pamuksuz

Large language models (LLMs) have emerged as promising tools for assisting in medical tasks, yet processing Electronic Health Records (EHRs) presents unique challenges due to their longitudinal nature. While LLMs' capabilities to perform…

人工智能 · 计算机科学 2025-03-07 Hejie Cui , Alyssa Unell , Bowen Chen , Jason Alan Fries , Emily Alsentzer , Sanmi Koyejo , Nigam Shah

Scalable and generalizable analysis of brain activity is essential for advancing both clinical diagnostics and cognitive research. Electroencephalography (EEG), a non-invasive modality with high temporal resolution, has been widely used for…

机器学习 · 计算机科学 2025-12-01 Sha Zhao , Mingyi Peng , Haiteng Jiang , Tao Li , Shijian Li , Gang Pan

There are two main barriers to using large language models (LLMs) in clinical reasoning. Firstly, while LLMs exhibit significant promise in Natural Language Processing (NLP) tasks, their performance in complex reasoning and planning falls…

人工智能 · 计算机科学 2024-12-31 Shengxin Hong , Liang Xiao , Xin Zhang , Jianxia Chen

Electronic Health Records (EHRs) play an important role in the healthcare system. However, their complexity and vast volume pose significant challenges to data interpretation and analysis. Recent advancements in Artificial Intelligence…