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Alzheimer's disease (AD), characterized by progressive cognitive decline and memory loss, presents a formidable global health challenge, underscoring the critical importance of early and precise diagnosis for timely interventions and…

图像与视频处理 · 电气工程与系统科学 2024-10-01 Arindam Majee , Avisek Gupta , Sourav Raha , Swagatam Das

Being the most commonly known neurodegeneration, Alzheimer's Disease (AD) is annually diagnosed in millions of patients. The present medical scenario still finds the exact diagnosis and classification of AD through neuroimaging data as a…

图像与视频处理 · 电气工程与系统科学 2025-03-19 Shravan Venkatraman , Pandiyaraju V , Abeshek A , Pavan Kumar S , Aravintakshan S A

Brain networks from functional MRI have advanced our understanding of cortical activity and its disruption in neurodegenerative disorders. Recent work has increasingly focused on dynamic (time-varying) brain networks that capture both…

神经元与认知 · 定量生物学 2026-04-14 Nicolas Rubido , Venia Batziou , Marwan Fuad , Vesna Vuksanovic

Structural magnetic resonance imaging (sMRI) can identify subtle brain changes due to its high contrast for soft tissues and high spatial resolution. It has been widely used in diagnosing neurological brain diseases, such as Alzheimer…

图像与视频处理 · 电气工程与系统科学 2023-11-14 Xin Zhang , Liangxiu Han , Lianghao Han , Haoming Chen , Darren Dancey , Daoqiang Zhang

Alzheimer diseases (ADs) involves cognitive decline and abnormal brain protein accumulation, necessitating timely diagnosis for effective treatment. Therefore, CAD systems leveraging deep learning advancements have demonstrated success in…

图像与视频处理 · 电气工程与系统科学 2024-05-28 Saddam Hussain Khan

Accurate and early diagnosis of Alzheimer's disease (AD) is critical for effective intervention and requires integrating complementary information from multimodal neuroimaging data. However, conventional fusion approaches often rely on…

Effective and accurate diagnosis of Alzheimer's disease (AD) or mild cognitive impairment (MCI) can be critical for early treatment and thus has attracted more and more attention nowadays. Since first introduced, machine learning methods…

计算机视觉与模式识别 · 计算机科学 2014-04-29 Fayao Liu , Chunhua Shen

Alzheimer's disease is estimated to affect around 50 million people worldwide and is rising rapidly, with a global economic burden of nearly a trillion dollars. This calls for scalable, cost-effective, and robust methods for detection of…

音频与语音处理 · 电气工程与系统科学 2020-09-03 Utkarsh Sarawgi , Wazeer Zulfikar , Nouran Soliman , Pattie Maes

Prediction of the cognitive evolution of a person susceptible to develop a neurodegenerative disorder is crucial to provide an appropriate treatment as soon as possible. In this paper we propose a 3D siamese network designed to extract…

图像与视频处理 · 电气工程与系统科学 2019-09-04 Cecilia Ostertag , Marie Beurton-Aimar , Thierry Urruty

Mild cognitive impairment (MCI) is the prodromal stage of Alzheimer's disease (AD) and thus enrolling MCI subjects to undergo clinical trials is worthwhile. However, MCI groups usually show significant diversity and heterogeneity in the…

定量方法 · 定量生物学 2025-08-26 Muheng Shang , Jin Zhang , Junwei Han , Lei Du

Machine Learning (ML) has emerged as a promising approach in healthcare, outperforming traditional statistical techniques. However, to establish ML as a reliable tool in clinical practice, adherence to best practices regarding data…

图像与视频处理 · 电气工程与系统科学 2023-09-15 Rosanna Turrisi , Alessandro Verri , Annalisa Barla

Accurately detecting Alzheimer's disease (AD) and predicting mini-mental state examination (MMSE) score are important tasks in elderly health by magnetic resonance imaging (MRI). Most of the previous methods on these two tasks are based on…

图像与视频处理 · 电气工程与系统科学 2023-07-10 Xu Tian , Jin Liu , Hulin Kuang , Yu Sheng , Jianxin Wang , The Alzheimer's Disease Neuroimaging Initiative

The most frequent kind of dementia of the nervous system, Alzheimer's disease, weakens several brain processes (such as memory) and eventually results in death. The clinical study uses magnetic resonance imaging to diagnose AD. Deep…

图像与视频处理 · 电气工程与系统科学 2023-10-30 Sarasadat Foroughipoor , Kimia Moradi , Hamidreza Bolhasani

Cognitive decline due to Alzheimer's disease (AD) is closely associated with brain structure alterations captured by structural magnetic resonance imaging (sMRI). It supports the validity to develop sMRI-based univariate neurodegeneration…

计算机视觉与模式识别 · 计算机科学 2020-10-28 Gang Wang , Qunxi Dong , Jianfeng Wu , Yi Su , Kewei Chen , Qingtang Su , Xiaofeng Zhang , Jinguang Hao , Tao Yao , Li Liu , Caiming Zhang , Richard J Caselli , Eric M Reiman , Yalin Wang

Alzheimer's disease (AD) is an irreversible neurodegenerative disorder that progressively destroys memory and other cognitive domains of the brain. While effective therapeutic management of AD is still in development, it seems reasonable to…

图像与视频处理 · 电气工程与系统科学 2020-11-10 Oleg Michailovich , Rinat Mukhometzianov

Magnetic resonance imaging (MRI) is a common technique to scan brains for strokes, tumors, and other abnormalities that cause forms of dementia. However, correctly diagnosing forms of dementia from MRIs is difficult, as nearly 1 in 3…

量子物理 · 物理学 2023-05-16 Ryan Kim

In the complex realm of cognitive disorders, Alzheimer's disease (AD) and vascular dementia (VaD) are the two most prevalent dementia types, presenting entangled symptoms yet requiring distinct treatment approaches. The crux of effective…

图像与视频处理 · 电气工程与系统科学 2024-11-08 Salma Hassan , Dawlat Akaila , Maryam Arjemandi , Vijay Papineni , Mohammad Yaqub

We propose a mesh-based technique to aid in the classification of Alzheimer's disease dementia (ADD) using mesh representations of the cortex and subcortical structures. Deep learning methods for classification tasks that utilize structural…

图像与视频处理 · 电气工程与系统科学 2022-03-14 Emanuel A. Azcona , Pierre Besson , Yunan Wu , Arjun Punjabi , Adam Martersteck , Amil Dravid , Todd B. Parrish , S. Kathleen Bandt , Aggelos K. Katsaggelos

Accurate predictions of conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) can enable effective personalized therapy. While cognitive tests and clinical data are routinely collected, they lack the predictive power…

机器学习 · 计算机科学 2025-11-11 Richard Hou , Shengpu Tang , Wei Jin

Resting state functional magnetic resonance images (fMRI) are commonly used for classification of patients as having Alzheimer's disease (AD), mild cognitive impairment (MCI), or being cognitive normal (CN). Most methods use time-series…

图像与视频处理 · 电气工程与系统科学 2021-04-22 Nazanin Beheshti , Lennart Johnsson