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High-dimensional sparse modeling with censored survival data is of great practical importance, as exemplified by modern applications in high-throughput genomic data analysis and credit risk analysis. In this article, we propose a class of…

统计方法学 · 统计学 2014-03-19 Wei Lin , Jinchi Lv

In this work, we are interested in studying the causal effect of an endogenous binary treatment on a dependently censored duration outcome. By dependent censoring, it is meant that the duration time ($T$) and right censoring time ($C$) are…

计量经济学 · 经济学 2025-04-04 Gilles Crommen , Jad Beyhum , Ingrid Van Keilegom

In this paper, we propose a new semiparametric regression estimator by using a hybrid technique of a parametric approach and a nonparametric penalized spline method. The overall shape of the true regression function is captured by the…

统计理论 · 数学 2012-02-17 Takuma Yoshida , Kanta Naito

We propose a new method for the analysis of competing risks data with long term survivors. The proposed method enables us to estimate the overall survival probability and cure fraction simultaneously. We formulate the effect of covariates…

统计理论 · 数学 2022-04-28 Sudheesh K Kattumannil , Sreedevi E P , Sankaran P G

Longitudinal studies could be complicated by left-censored repeated measures. For example, in Human Immunodeficiency Virus infection, there is a detection limit of the assay used to quantify the plasma viral load. Simple imputation of the…

应用统计 · 统计学 2007-05-23 Rodolphe Thiébaut , Hélène Jacqmin-Gadda

Predictive recursion is an accurate and computationally efficient algorithm for nonparametric estimation of mixing densities in mixture models. In semiparametric mixture models, however, the algorithm fails to account for any uncertainty in…

统计方法学 · 统计学 2015-03-19 Ryan Martin , Surya T. Tokdar

We consider a non-proportional hazards model where the regression coefficient is not constant but piecewise constant. Following Andersen and Gill (1982), we know that a knowledge of the changepoint leads to a relatively straightforward…

应用统计 · 统计学 2016-10-11 Roxane Duroux , John O'Quigley

Survival analysis is a widely used statistical framework for modeling time-to-event data under censoring. Classical methods, such as the Cox proportional hazards (Cox PH) model, offer a semiparametric approach to estimating the effects of…

机器学习 · 统计学 2026-04-23 Yang Xu , Wenbin Lu , Rui Song

Accurate time-to-event prediction is integral to decision-making, informing medical guidelines, hiring decisions, and resource allocation. Survival analysis, the quantitative framework used to model time-to-event data, accounts for patients…

机器学习 · 计算机科学 2025-08-08 Vincent Jeanselme , Brian Tom , Jessica Barrett

We propose new parametric frameworks of regression analysis with the conditional mode of a bounded response as the focal point of interest. Covariate effects estimation and prediction based on the maximum likelihood method under two new…

统计方法学 · 统计学 2020-06-22 Haiming Zhou , Xianzheng Huang

Here we propose a novel searching scheme for a tuning parameter in high-dimensional penalized regression methods to address variable selection and modeling when sample sizes are limited compared to the data dimensions. Our method is…

定量方法 · 定量生物学 2020-02-11 Tao Jiang , Stephanie J. London , Mi Kyeong Lee , Josyf C. Mychaleckyj , Alison A. Motsinger-Reif

We propose a method to quantify uncertainty around individual survival distribution estimates using right-censored data, compatible with any survival model. Unlike classical confidence intervals, the survival bands produced by this method…

统计方法学 · 统计学 2025-12-18 Matteo Sesia , Vladimir Svetnik

We propose a deep generative approach to nonparametric estimation of conditional survival and hazard functions with right-censored data. The key idea of the proposed method is to first learn a conditional generator for the joint conditional…

统计理论 · 数学 2022-05-20 Xingyu Zhou , Wen Su , Changyu Liu , Yuling Jiao , Xingqiu Zhao , Jian Huang

Proportional hazards (PH), proportional odds (PO) and accelerated failure time (AFT) models have been widely used to deal with survival data in different fields of knowledge. Despite their popularity, such models are not suitable to handle…

统计方法学 · 统计学 2019-10-08 Fabio N. Demarqui , Vinicius D. Mayrink

We consider a flexible semiparametric quantile regression model for analyzing high dimensional heterogeneous data. This model has several appealing features: (1) By considering different conditional quantiles, we may obtain a more complete…

统计理论 · 数学 2016-01-25 Ben Sherwood , Lan Wang

This paper compares six different parameter estimation methods for shared frailty models via a series of simulation studies. A shared frailty model is a survival model that incorporates a random effect term, where the frailties are common…

统计方法学 · 统计学 2023-11-21 Tingxuan Wu , Cindy Feng , Longhai Li

We propose a novel personalized concept for the optimal treatment selection for a situation where the response is a multivariate vector, that could contain right-censored variables such as survival time. The proposed method can be applied…

统计方法学 · 统计学 2022-10-03 Chathura Siriwardhana , K. B. Kulasekera , Somnath Datta

In this paper we address the challenges posed by non-proportional hazards and informative censoring, offering a path toward more meaningful causal inference conclusions. We start from the marginal structural Cox model, which has been widely…

统计方法学 · 统计学 2023-11-15 Jiyu Luo , Denise Rava , Jelena Bradic , Ronghui Xu

In this article, we develop nonparametric inference methods for comparing survival data across two samples, which are beneficial for clinical trials of novel cancer therapies where long-term survival is a critical outcome. These therapies,…

统计方法学 · 统计学 2024-09-05 Yi-Cheng Tai , Weijing Wang , Martin T. Wells

We propose a semiparametric framework for causal inference with right-censored survival outcomes and many weak invalid instruments, motivated by Mendelian randomization in biobank studies where classical methods may fail. We adopt an…

统计方法学 · 统计学 2025-10-06 Qiushi Bu , Wen Su , Xingqiu Zhao , Zhonghua Liu